PROJECT #16994 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 01 December 2022 06:13:29

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 01 December 2022 06:13:29

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 5900X 12-CORE 24 41,842 1,004,208 AMD
2 RYZEN 9 7950X 16-CORE 32 25,930 829,760 AMD
3 RYZEN 7 5700G 16 40,649 650,384 AMD
4 RYZEN 7 5800X 8-CORE 16 40,593 649,488 AMD
5 12TH GEN CORE I7-12700K 20 25,322 506,440 Intel
6 RYZEN 9 3950X 16-CORE 32 15,697 502,304 AMD
7 RYZEN 9 5950X 16-CORE 32 14,489 463,648 AMD
8 RYZEN 7 5700X 8-CORE 16 28,461 455,376 AMD
9 11TH GEN CORE I7-11700K @ 3.60GHZ 16 24,603 393,648 Intel
10 11TH GEN CORE I9-11900K @ 3.50GHZ 16 24,294 388,704 Intel
11 CORE I9-10900X CPU @ 3.70GHZ 20 15,401 308,020 Intel
12 CORE I9-9900K CPU @ 3.60GHZ 16 17,122 273,952 Intel
13 RYZEN 7 3800X 8-CORE 16 16,573 265,168 AMD
14 RYZEN 7 5800H 16 15,794 252,704 AMD
15 RYZEN 9 3900X 12-CORE 24 10,430 250,320 AMD
16 RYZEN 5 5600X 6-CORE 12 20,485 245,820 AMD
17 CORE I9-10850K CPU @ 3.60GHZ 20 11,975 239,500 Intel
18 CORE I7-8700 CPU @ 3.20GHZ 12 19,646 235,752 Intel
19 XEON CPU E5-2650 V2 @ 2.60GHZ 32 6,716 214,912 Intel
20 XEON CPU E5-2680 V3 @ 2.50GHZ 24 8,767 210,408 Intel
21 CORE I7-9700 CPU @ 3.00GHZ 8 23,508 188,064 Intel
22 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,684 187,152 Intel
23 RYZEN 7 PRO 4750G 16 10,830 173,280 AMD
24 RYZEN 7 3700X 8-CORE 16 10,794 172,704 AMD
25 RYZEN 5 3600 6-CORE 12 13,881 166,572 AMD
26 CORE I7-9700K CPU @ 3.60GHZ 8 18,336 146,688 Intel
27 RYZEN 7 2700X EIGHT-CORE 16 8,565 137,040 AMD
28 APPLE M1 MAX 10 13,465 134,650 Apple
29 XEON GOLD 6128 CPU @ 3.40GHZ 12 9,997 119,964 Intel
30 RYZEN 5 2600X SIX-CORE 12 8,988 107,856 AMD
31 CORE I7-10700T CPU @ 2.00GHZ 16 6,655 106,480 Intel
32 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,765 105,180 Intel
33 RYZEN 5 1600 SIX-CORE 12 7,068 84,816 AMD
34 CORE I7-4790K CPU @ 4.00GHZ 8 10,375 83,000 Intel
35 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,328 82,624 Intel
36 CORE I7-4790 CPU @ 3.60GHZ 8 9,698 77,584 Intel
37 XEON W-10855M CPU @ 2.80GHZ 12 6,307 75,684 Intel
38 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,705 61,640 Intel
39 APPLE M1 8 7,332 58,656 Apple
40 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,103 56,824 Intel
41 CORE I7-6700K CPU @ 4.00GHZ 8 7,018 56,144 Intel
42 CORE I7-4790T CPU @ 2.70GHZ 8 6,399 51,192 Intel
43 CORE I5-9300H CPU @ 2.40GHZ 8 6,141 49,128 Intel
44 APPLE M1 PRO 10 4,855 48,550 Apple
45 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 5,329 42,632 Intel
46 CORE I7-7700HQ CPU @ 2.80GHZ 8 5,315 42,520 Intel
47 CORE I7-2760QM CPU @ 2.40GHZ 8 2,489 19,912 Intel
48 XEON CPU E5-2697 V2 @ 2.70GHZ 24 552 13,248 Intel