PROJECT #16994 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 5900X 12-CORE 24 44,737 1,073,688 AMD
2 RYZEN 7 5800X 8-CORE 16 40,593 649,488 AMD
3 12TH GEN CORE I7-12700K 20 31,324 626,480 Intel
4 RYZEN 9 3950X 16-CORE 32 17,588 562,816 AMD
5 RYZEN 7 5700X 8-CORE 16 30,267 484,272 AMD
6 RYZEN 9 5950X 16-CORE 32 12,416 397,312 AMD
7 11TH GEN CORE I9-11900K @ 3.50GHZ 16 24,294 388,704 Intel
8 CORE I9-10850K CPU @ 3.60GHZ 20 16,760 335,200 Intel
9 RYZEN 7 3800X 8-CORE 16 18,655 298,480 AMD
10 CORE I9-10900X CPU @ 3.70GHZ 20 14,822 296,440 Intel
11 RYZEN 7 5800H 16 17,422 278,752 AMD
12 CORE I9-9900K CPU @ 3.60GHZ 16 16,520 264,320 Intel
13 RYZEN 9 3900X 12-CORE 24 10,267 246,408 AMD
14 CORE I7-8700 CPU @ 3.20GHZ 12 19,646 235,752 Intel
15 XEON CPU E5-2680 V3 @ 2.50GHZ 24 8,767 210,408 Intel
16 CORE I7-9700 CPU @ 3.00GHZ 8 23,508 188,064 Intel
17 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,684 187,152 Intel
18 RYZEN 7 PRO 4750G 16 11,687 186,992 AMD
19 RYZEN 5 5600X 6-CORE 12 12,990 155,880 AMD
20 CORE I7-9700K CPU @ 3.60GHZ 8 18,336 146,688 Intel
21 RYZEN 5 3600 6-CORE 12 11,741 140,892 AMD
22 RYZEN 7 2700X EIGHT-CORE 16 8,565 137,040 AMD
23 RYZEN 7 3700X 8-CORE 16 8,277 132,432 AMD
24 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,765 105,180 Intel
25 RYZEN 5 1600 SIX-CORE 12 7,068 84,816 AMD
26 CORE I7-4790K CPU @ 4.00GHZ 8 10,375 83,000 Intel
27 CORE I7-4790 CPU @ 3.60GHZ 8 9,698 77,584 Intel
28 XEON W-10855M CPU @ 2.80GHZ 12 6,307 75,684 Intel
29 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,705 61,640 Intel
30 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,103 56,824 Intel
31 CORE I7-4790T CPU @ 2.70GHZ 8 6,399 51,192 Intel
32 CORE I5-9300H CPU @ 2.40GHZ 8 6,141 49,128 Intel