1. Projects
  2. Research Project Folding Profile

PROJECT #16994 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 13TH GEN CORE I9-13900KS 32 26,057 833,824 Intel
2 RYZEN 9 7950X 16-CORE 32 25,930 829,760 AMD
3 RYZEN 9 5900X 12-CORE 24 29,924 718,176 AMD
4 RYZEN 7 5800X 8-CORE 16 40,154 642,464 AMD
5 RYZEN 7 7700X 8-CORE 16 38,544 616,704 AMD
6 RYZEN 9 5950X 16-CORE 32 16,426 525,632 AMD
7 12TH GEN CORE I7-12700K 20 25,322 506,440 Intel
8 RYZEN 9 3950X 16-CORE 32 15,697 502,304 AMD
9 RYZEN 7 5700X 8-CORE 16 26,441 423,056 AMD
10 11TH GEN CORE I7-11700K @ 3.60GHZ 16 25,283 404,528 Intel
11 11TH GEN CORE I9-11900K @ 3.50GHZ 16 24,294 388,704 Intel
12 RYZEN 7 5800X3D 8-CORE 16 23,764 380,224 AMD
13 CORE I9-10900X CPU @ 3.70GHZ 20 15,401 308,020 Intel
14 RYZEN 7 5700G 16 17,225 275,600 AMD
15 CORE I9-9900K CPU @ 3.60GHZ 16 17,122 273,952 Intel
16 RYZEN 7 3800X 8-CORE 16 17,087 273,392 AMD
17 RYZEN 7 5800H 16 15,794 252,704 AMD
18 RYZEN 9 3900X 12-CORE 24 10,430 250,320 AMD
19 RYZEN 5 5600X 6-CORE 12 20,485 245,820 AMD
20 CORE I9-10850K CPU @ 3.60GHZ 20 11,975 239,500 Intel
21 CORE I7-8700 CPU @ 3.20GHZ 12 19,646 235,752 Intel
22 XEON CPU E5-2650 V2 @ 2.60GHZ 32 6,716 214,912 Intel
23 XEON CPU E5-2680 V3 @ 2.50GHZ 24 8,767 210,408 Intel
24 CORE I7-9700K CPU @ 3.60GHZ 8 25,081 200,648 Intel
25 XEON W-2245 CPU @ 3.90GHZ 16 12,143 194,288 Intel
26 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,684 187,152 Intel
27 CORE I7-9700 CPU @ 3.00GHZ 8 21,860 174,880 Intel
28 RYZEN 7 3700X 8-CORE 16 10,794 172,704 AMD
29 RYZEN 7 PRO 4750G 16 10,629 170,064 AMD
30 RYZEN 5 3600 6-CORE 12 14,108 169,296 AMD
31 12TH GEN CORE I9-12900K 24 5,968 143,232 Intel
32 RYZEN 7 2700X EIGHT-CORE 16 8,565 137,040 AMD
33 APPLE M1 MAX 10 13,465 134,650 Apple
34 CORE I7-5930K CPU @ 3.50GHZ 12 10,042 120,504 Intel
35 XEON GOLD 6128 CPU @ 3.40GHZ 12 9,997 119,964 Intel
36 CORE I7-6800K CPU @ 3.40GHZ 12 9,291 111,492 Intel
37 RYZEN 5 2600X SIX-CORE 12 8,988 107,856 AMD
38 CORE I7-10700T CPU @ 2.00GHZ 16 6,655 106,480 Intel
39 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,765 105,180 Intel
40 CORE I7-8705G CPU @ 3.10GHZ 8 11,073 88,584 Intel
41 RYZEN 5 1600 SIX-CORE 12 7,068 84,816 AMD
42 CORE I7-4790K CPU @ 4.00GHZ 8 10,375 83,000 Intel
43 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,328 82,624 Intel
44 CORE I7-4790 CPU @ 3.60GHZ 8 9,698 77,584 Intel
45 XEON CPU E5-2670 0 @ 2.60GHZ 32 2,369 75,808 Intel
46 XEON W-10855M CPU @ 2.80GHZ 12 6,307 75,684 Intel
47 CORE I7-5820K CPU @ 3.30GHZ 12 5,376 64,512 Intel
48 APPLE M1 8 7,873 62,984 Apple
49 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,705 61,640 Intel
50 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,259 58,072 Intel
51 CORE I7-6700K CPU @ 4.00GHZ 8 6,945 55,560 Intel
52 CORE I7-4790T CPU @ 2.70GHZ 8 6,399 51,192 Intel
53 CORE I5-9300H CPU @ 2.40GHZ 8 6,141 49,128 Intel
54 APPLE M1 PRO 10 4,855 48,550 Apple
55 CORE I7-7700HQ CPU @ 2.80GHZ 8 5,408 43,264 Intel
56 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 5,329 42,632 Intel
57 XEON CPU E5-2697 V2 @ 2.70GHZ 24 1,298 31,152 Intel
58 CORE I5-10210U CPU @ 1.60GHZ 7 3,158 22,106 Intel
59 CORE I7-2760QM CPU @ 2.40GHZ 8 2,489 19,912 Intel
60 11TH GEN CORE I3-1125G4 @ 2.00GHZ 8 2,476 19,808 Intel