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PROJECT #16953 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 23 May 2022 03:34:45

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 23 May 2022 03:34:45

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 25,775 824,800 AMD
2 RYZEN 9 5950X 16-CORE 32 15,782 505,024 AMD
3 RYZEN 7 5800X 8-CORE 16 26,473 423,568 AMD
4 RYZEN 9 5900X 12-CORE 24 16,535 396,840 AMD
5 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,100 388,800 AMD
6 RYZEN 9 3900 12-CORE 24 13,916 333,984 AMD
7 RYZEN 9 3900XT 12-CORE 24 13,913 333,912 AMD
8 CORE I7-10700K CPU @ 3.80GHZ 16 19,098 305,568 Intel
9 11TH GEN CORE I7-11700K @ 3.60GHZ 16 18,156 290,496 Intel
10 RYZEN 9 3900X 12-CORE 24 11,951 286,824 AMD
11 CORE I9-10900X CPU @ 3.70GHZ 20 13,908 278,160 Intel
12 CORE I9-7920X CPU @ 2.90GHZ 24 11,096 266,304 Intel
13 XEON CPU E5-2690 V4 @ 2.60GHZ 28 9,414 263,592 Intel
14 RYZEN 5 5600X 6-CORE 12 21,007 252,084 AMD
15 RYZEN THREADRIPPER 3960X 24-CORE 48 4,815 231,120 AMD
16 CORE I7-10700F CPU @ 2.90GHZ 16 14,055 224,880 Intel
17 EPYC 7302P 16-CORE 32 7,019 224,608 AMD
18 RYZEN 7 3800X 8-CORE 16 13,426 214,816 AMD
19 RYZEN 7 3700X 8-CORE 16 12,851 205,616 AMD
20 CORE I7-8700K CPU @ 3.70GHZ 12 16,721 200,652 Intel
21 RYZEN 9 4900HS 16 11,394 182,304 AMD
22 XEON CPU E5-2660 0 @ 2.20GHZ 32 5,685 181,920 Intel
23 CORE I7-8700 CPU @ 3.20GHZ 12 14,887 178,644 Intel
24 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,343 176,232 Intel
25 RYZEN 5 3600 6-CORE 12 14,482 173,784 AMD
26 CORE I7-10700 CPU @ 2.90GHZ 16 10,787 172,592 Intel
27 XEON CPU E5-2690 V2 @ 3.00GHZ 20 8,029 160,580 Intel
28 CORE I5-10400F CPU @ 2.90GHZ 12 13,010 156,120 Intel
29 RYZEN 7 2700X EIGHT-CORE 16 9,676 154,816 AMD
30 RYZEN 7 4800H 16 9,553 152,848 AMD
31 CORE I5-10400 CPU @ 2.90GHZ 12 12,067 144,804 Intel
32 CORE I7-10870H CPU @ 2.20GHZ 16 8,839 141,424 Intel
33 RYZEN 3 3100 4-CORE 8 15,608 124,864 AMD
34 CORE I7-9700T CPU @ 2.00GHZ 8 15,525 124,200 Intel
35 RYZEN THREADRIPPER 2950X 16-CORE 32 3,845 123,040 AMD
36 RYZEN 5 3600XT 6-CORE 12 10,067 120,804 AMD
37 CORE I7-9700K CPU @ 3.60GHZ 8 15,057 120,456 Intel
38 CORE I5-9400F CPU @ 2.90GHZ 6 19,473 116,838 Intel
39 RYZEN 5 1600 SIX-CORE 12 9,109 109,308 AMD
40 CORE I7-4790K CPU @ 4.00GHZ 8 12,202 97,616 Intel
41 RYZEN 5 2600 SIX-CORE 12 7,532 90,384 AMD
42 XEON CPU E5-2620 V2 @ 2.10GHZ 24 3,492 83,808 Intel
43 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 10,394 83,152 Intel
44 CORE I7-6700HQ CPU @ 2.60GHZ 8 10,303 82,424 Intel
45 CORE I5-8400 CPU @ 2.80GHZ 6 13,654 81,924 Intel
46 CORE I7-8705G CPU @ 3.10GHZ 8 9,668 77,344 Intel
47 CORE I7-6700K CPU @ 4.00GHZ 8 9,384 75,072 Intel
48 XEON CPU E5-2690 V3 @ 2.60GHZ 12 6,162 73,944 Intel
49 CORE I5-8300H CPU @ 2.30GHZ 8 8,097 64,776 Intel
50 XEON CPU E3-1241 V3 @ 3.50GHZ 8 7,549 60,392 Intel
51 XEON W-10855M CPU @ 2.80GHZ 12 5,030 60,360 Intel
52 CORE I7-1068NG7 CPU @ 2.30GHZ 8 7,515 60,120 Intel
53 CORE I7-3840QM CPU @ 2.80GHZ 8 6,863 54,904 Intel
54 CORE I7-4790T CPU @ 2.70GHZ 8 6,435 51,480 Intel
55 XEON CPU X5670 @ 2.93GHZ 12 4,248 50,976 Intel
56 CORE I7-8550U CPU @ 1.80GHZ 8 6,343 50,744 Intel
57 XEON CPU E5-2650 0 @ 2.00GHZ 16 3,087 49,392 Intel
58 CORE I7-3770 CPU @ 3.40GHZ 8 6,134 49,072 Intel
59 XEON CPU E3-1230 V2 @ 3.30GHZ 8 5,886 47,088 Intel
60 CORE I7-3610QM CPU @ 2.30GHZ 8 4,332 34,656 Intel
61 CORE I7-2600 CPU @ 3.40GHZ 8 2,891 23,128 Intel