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PROJECT #16923 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 07 February 2023 12:14:59

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 07 February 2023 12:14:59

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 CELERON(R) CPU N3350 @ 1.10GHZ 2 298,977 597,954 Intel
2 RYZEN 9 3900XT 12-CORE 24 18,241 437,784 AMD
3 CORE I9-9900K CPU @ 3.60GHZ 16 21,943 351,088 Intel
4 RYZEN 9 5950X 16-CORE 32 8,212 262,784 AMD
5 RYZEN THREADRIPPER 3960X 24-CORE 48 5,441 261,168 AMD
6 RYZEN 9 3950X 16-CORE 32 8,089 258,848 AMD
7 RYZEN 9 5900X 12-CORE 24 10,306 247,344 AMD
8 CORE I9-9980XE CPU @ 3.00GHZ 36 5,921 213,156 Intel
9 RYZEN 9 3900X 12-CORE 24 8,191 196,584 AMD
10 RYZEN 7 5800X 8-CORE 16 11,816 189,056 AMD
11 CORE I9-7920X CPU @ 2.90GHZ 24 7,781 186,744 Intel
12 RYZEN THREADRIPPER 2970WX 24-CORE 48 3,848 184,704 AMD
13 CORE I7-4790 CPU @ 3.60GHZ 8 21,650 173,200 Intel
14 CORE I9-10900K CPU @ 3.70GHZ 20 7,929 158,580 Intel
15 CORE I7-5960X CPU @ 3.00GHZ 16 9,286 148,576 Intel
16 RYZEN 7 3700X 8-CORE 16 8,862 141,792 AMD
17 CORE I7-9700K CPU @ 3.60GHZ 8 17,585 140,680 Intel
18 XEON CPU E5-2690 V2 @ 3.00GHZ 20 6,678 133,560 Intel
19 CORE I7-9700 CPU @ 3.00GHZ 8 16,616 132,928 Intel
20 RYZEN 5 3600X 6-CORE 12 10,932 131,184 AMD
21 RYZEN 5 3600 6-CORE 12 10,332 123,984 AMD
22 RYZEN 5 1600X SIX-CORE 12 10,172 122,064 AMD
23 RYZEN 5 3500 6-CORE 6 18,682 112,092 AMD
24 RYZEN 7 3800X 8-CORE 16 6,901 110,416 AMD
25 RYZEN 5 2600X SIX-CORE 12 9,124 109,488 AMD
26 CORE2 DUO CPU T7700 @ 2.40GHZ 12 8,733 104,796 Intel
27 CORE I7-4870HQ CPU @ 2.50GHZ 8 12,839 102,712 Intel
28 RYZEN 7 4800H 16 6,305 100,880 AMD
29 CORE I5-9600K CPU @ 3.70GHZ 6 16,005 96,030 Intel
30 RYZEN 5 3600XT 6-CORE 12 7,774 93,288 AMD
31 RYZEN 7 2700X EIGHT-CORE 16 5,637 90,192 AMD
32 CORE I5-9400F CPU @ 2.90GHZ 6 14,433 86,598 Intel
33 CORE I9-9900 CPU @ 3.10GHZ 16 5,306 84,896 Intel
34 CORE I3-6100 CPU @ 3.70GHZ 4 20,643 82,572 Intel
35 RYZEN 7 1700 EIGHT-CORE 16 4,728 75,648 AMD
36 CORE I7-6700K CPU @ 4.00GHZ 8 9,369 74,952 Intel
37 CORE I7-8700K CPU @ 3.70GHZ 12 6,236 74,832 Intel
38 CORE I7-6820HQ CPU @ 2.70GHZ 8 9,108 72,864 Intel
39 RYZEN 5 4600HS 12 5,604 67,248 AMD
40 CORE I7-4790K CPU @ 4.00GHZ 8 7,297 58,376 Intel
41 CORE I7-8550U CPU @ 1.80GHZ 8 7,283 58,264 Intel
42 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,399 57,576 Intel
43 RYZEN 5 2600 SIX-CORE 12 4,768 57,216 AMD
44 CORE I7-8705G CPU @ 3.10GHZ 8 7,065 56,520 Intel
45 CORE I5-7600 CPU @ 3.50GHZ 4 12,273 49,092 Intel
46 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,071 48,568 Intel
47 CORE I5-6500 CPU @ 3.20GHZ 4 11,904 47,616 Intel
48 CORE I5-7400 CPU @ 3.00GHZ 4 10,877 43,508 Intel
49 CORE I7-3770 CPU @ 3.40GHZ 8 4,419 35,352 Intel
50 RYZEN 5 1400 QUAD-CORE 8 4,227 33,816 AMD
51 RYZEN 7 4700U 8 4,223 33,784 AMD
52 XEON CPU E5-2609 V2 @ 2.50GHZ 8 4,189 33,512 Intel
53 XEON CPU E3-1230 V2 @ 3.30GHZ 8 4,146 33,168 Intel
54 CORE I7-8565U CPU @ 1.80GHZ 8 3,769 30,152 Intel
55 CORE I7-1065G7 CPU @ 1.30GHZ 8 3,099 24,792 Intel
56 PHENOM II X6 1090T 6 3,526 21,156 AMD
57 FX-8350 EIGHT-CORE 8 2,477 19,816 AMD
58 CORE I5-10210U CPU @ 1.60GHZ 7 2,775 19,425 Intel
59 FX-9590 EIGHT-CORE 8 2,225 17,800 AMD
60 CORE I3-7100 CPU @ 3.90GHZ 4 4,065 16,260 Intel
61 CORE I5-6200U CPU @ 2.30GHZ 4 3,607 14,428 Intel
62 CORE I7 CPU 860 @ 2.80GHZ 8 1,736 13,888 Intel
63 FX-8320 EIGHT-CORE 8 1,666 13,328 AMD
64 PENTIUM(R) SILVER N5000 CPU @ 1.10GHZ 4 2,751 11,004 Intel
65 PHENOM II X4 965 4 2,345 9,380 AMD
66 CORE I3-6006U CPU @ 2.00GHZ 4 2,098 8,392 Intel
67 A8-6410 APU 4 261 1,044 AMD