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PROJECT #16930 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 27 January 2023 12:14:48

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Friday, 27 January 2023 12:14:48

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3900XT 12-CORE 24 19,828 475,872 AMD
2 CORE I9-9900K CPU @ 3.60GHZ 16 24,559 392,944 Intel
3 RYZEN THREADRIPPER 3960X 24-CORE 48 7,424 356,352 AMD
4 RYZEN 9 5900X 12-CORE 24 13,186 316,464 AMD
5 RYZEN 9 5950X 16-CORE 32 9,080 290,560 AMD
6 RYZEN 9 3950X 16-CORE 32 8,014 256,448 AMD
7 CORE I9-9980XE CPU @ 3.00GHZ 36 6,764 243,504 Intel
8 RYZEN 9 3900X 12-CORE 24 9,684 232,416 AMD
9 RYZEN 7 5800X 8-CORE 16 13,599 217,584 AMD
10 CORE I9-7920X CPU @ 2.90GHZ 24 8,824 211,776 Intel
11 CORE I7-5960X CPU @ 3.00GHZ 16 10,465 167,440 Intel
12 RYZEN THREADRIPPER 2970WX 24-CORE 48 3,357 161,136 AMD
13 RYZEN 7 3700X 8-CORE 16 9,978 159,648 AMD
14 RYZEN THREADRIPPER 2950X 16-CORE 32 4,866 155,712 AMD
15 CORE I7-9700 CPU @ 3.00GHZ 8 18,672 149,376 Intel
16 RYZEN 5 1600X SIX-CORE 12 12,344 148,128 AMD
17 RYZEN 5 3600X 6-CORE 12 12,192 146,304 AMD
18 XEON CPU E5-2690 V2 @ 3.00GHZ 20 7,315 146,300 Intel
19 CORE I7-9700K CPU @ 3.60GHZ 8 17,938 143,504 Intel
20 RYZEN 5 2600X SIX-CORE 12 11,840 142,080 AMD
21 RYZEN 5 3600 6-CORE 12 11,682 140,184 AMD
22 RYZEN 7 4800H 16 8,478 135,648 AMD
23 RYZEN 5 PRO 4650G 12 11,254 135,048 AMD
24 RYZEN 5 3500 6-CORE 6 21,250 127,500 AMD
25 RYZEN 7 3800X 8-CORE 16 7,687 122,992 AMD
26 CORE I5-9600K CPU @ 3.70GHZ 6 18,126 108,756 Intel
27 RYZEN THREADRIPPER 1920X 12-CORE 24 4,403 105,672 AMD
28 CORE2 DUO CPU T7700 @ 2.40GHZ 12 8,525 102,300 Intel
29 RYZEN 3 3100 4-CORE 8 12,665 101,320 AMD
30 CORE I5-9400F CPU @ 2.90GHZ 6 16,467 98,802 Intel
31 RYZEN 5 3600XT 6-CORE 12 7,933 95,196 AMD
32 CORE I7-8700K CPU @ 3.70GHZ 12 7,561 90,732 Intel
33 RYZEN 7 2700X EIGHT-CORE 16 5,527 88,432 AMD
34 RYZEN 7 1700 EIGHT-CORE 16 5,482 87,712 AMD
35 CORE I7-3840QM CPU @ 2.80GHZ 8 10,348 82,784 Intel
36 CORE I5-9300H CPU @ 2.40GHZ 8 10,233 81,864 Intel
37 CORE I7-5930K CPU @ 3.50GHZ 12 6,161 73,932 Intel
38 CORE I7-8550U CPU @ 1.80GHZ 8 8,861 70,888 Intel
39 RYZEN 5 3500X 6-CORE 6 11,633 69,798 AMD
40 CORE I7-4790K CPU @ 4.00GHZ 8 8,499 67,992 Intel
41 CORE I7-6820HQ CPU @ 2.70GHZ 8 8,407 67,256 Intel
42 CORE I7-8705G CPU @ 3.10GHZ 8 8,002 64,016 Intel
43 RYZEN 5 2600 SIX-CORE 12 5,252 63,024 AMD
44 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,558 61,392 Intel
45 CORE I7-4790 CPU @ 3.60GHZ 8 7,482 59,856 Intel
46 CORE I7-6800K CPU @ 3.40GHZ 12 4,931 59,172 Intel
47 CORE I7-6700K CPU @ 4.00GHZ 8 7,378 59,024 Intel
48 CORE I5-7600 CPU @ 3.50GHZ 4 14,066 56,264 Intel
49 CORE I5-6500 CPU @ 3.20GHZ 4 13,043 52,172 Intel
50 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,341 50,728 Intel
51 RYZEN 5 5600X 6-CORE 12 4,081 48,972 AMD
52 XEON E-2124G CPU @ 3.40GHZ 4 11,447 45,788 Intel
53 XEON W-2123 CPU @ 3.60GHZ 8 5,642 45,136 Intel
54 CORE I7-3770 CPU @ 3.40GHZ 8 5,072 40,576 Intel
55 CORE I5-8265U CPU @ 1.60GHZ 8 4,945 39,560 Intel
56 CORE I7-8565U CPU @ 1.80GHZ 8 4,799 38,392 Intel
57 XEON CPU E3-1230 V2 @ 3.30GHZ 8 4,196 33,568 Intel
58 A8-6410 APU 4 7,974 31,896 AMD
59 CORE I7-6700HQ CPU @ 2.60GHZ 8 3,570 28,560 Intel
60 CORE I7-8750H CPU @ 2.20GHZ 12 2,207 26,484 Intel
61 PHENOM II X6 1090T 6 3,903 23,418 AMD
62 FX-9590 EIGHT-CORE 8 2,836 22,688 AMD
63 CORE I7-2600K CPU @ 3.40GHZ 8 2,785 22,280 Intel
64 FX-8350 EIGHT-CORE 8 2,627 21,016 AMD
65 CORE I3-2120 CPU @ 3.30GHZ 4 4,968 19,872 Intel
66 CORE I3-7100 CPU @ 3.90GHZ 4 4,874 19,496 Intel
67 FX-8320 EIGHT-CORE 8 1,934 15,472 AMD
68 CORE I5-5200U CPU @ 2.20GHZ 4 3,772 15,088 Intel
69 CORE I5-3320M CPU @ 2.60GHZ 4 3,704 14,816 Intel
70 PHENOM II X4 965 4 3,033 12,132 AMD
71 CORE I3-6006U CPU @ 2.00GHZ 4 2,561 10,244 Intel
72 XEON CPU L5420 @ 2.50GHZ 4 2,454 9,816 Intel
73 RYZEN 5 3500U 8 1,053 8,424 AMD
74 CORE I5-10210U CPU @ 1.60GHZ 7 1,195 8,365 Intel
75 RYZEN 7 4700U 8 969 7,752 AMD
76 CORE I5-2540M CPU @ 2.60GHZ 4 1,647 6,588 Intel
77 FX-8300 EIGHT-CORE 8 703 5,624 AMD
78 CELERON(R) CPU G550 @ 2.60GHZ 2 1,851 3,702 Intel
79 CELERON(R) CPU N3350 @ 1.10GHZ 2 1,672 3,344 Intel