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PROJECT #16932 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 28 September 2022 00:18:15

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 28 September 2022 00:18:15

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 13,255 636,240 AMD
2 RYZEN 9 3900XT 12-CORE 24 19,932 478,368 AMD
3 CORE I9-9900K CPU @ 3.60GHZ 16 23,908 382,528 Intel
4 RYZEN 9 5900X 12-CORE 24 11,979 287,496 AMD
5 RYZEN 9 3950X 16-CORE 32 8,758 280,256 AMD
6 RYZEN 9 5950X 16-CORE 32 7,941 254,112 AMD
7 CORE I9-9980XE CPU @ 3.00GHZ 36 6,592 237,312 Intel
8 CORE I7-8700 CPU @ 3.20GHZ 12 19,710 236,520 Intel
9 RYZEN 9 3900X 12-CORE 24 9,468 227,232 AMD
10 RYZEN 7 5800X 8-CORE 16 13,122 209,952 AMD
11 CORE I9-7920X CPU @ 2.90GHZ 24 8,070 193,680 Intel
12 XEON PLATINUM 8124M CPU @ 3.00GHZ 36 4,767 171,612 Intel
13 RYZEN THREADRIPPER 2970WX 24-CORE 48 3,385 162,480 AMD
14 RYZEN 7 3800X 8-CORE 16 9,892 158,272 AMD
15 RYZEN 7 2700X EIGHT-CORE 16 9,841 157,456 AMD
16 RYZEN 7 3700X 8-CORE 16 9,672 154,752 AMD
17 RYZEN 5 1600X SIX-CORE 12 12,690 152,280 AMD
18 CORE I7-5960X CPU @ 3.00GHZ 16 9,242 147,872 Intel
19 CORE I7-9700 CPU @ 3.00GHZ 8 18,462 147,696 Intel
20 CORE I7-9700K CPU @ 3.60GHZ 8 18,349 146,792 Intel
21 XEON CPU E5-2690 V2 @ 3.00GHZ 20 7,165 143,300 Intel
22 RYZEN 5 3600X 6-CORE 12 11,773 141,276 AMD
23 RYZEN 5 3600 6-CORE 12 11,212 134,544 AMD
24 RYZEN 5 2600X SIX-CORE 12 10,436 125,232 AMD
25 RYZEN 7 4800H 16 7,735 123,760 AMD
26 RYZEN 5 3500 6-CORE 6 20,278 121,668 AMD
27 CORE I7-8700K CPU @ 3.70GHZ 12 9,971 119,652 Intel
28 CORE2 DUO CPU T7700 @ 2.40GHZ 12 9,140 109,680 Intel
29 CORE I5-9600K CPU @ 3.70GHZ 6 17,939 107,634 Intel
30 CORE I5-8400 CPU @ 2.80GHZ 6 17,114 102,684 Intel
31 CORE I5-9400F CPU @ 2.90GHZ 6 15,740 94,440 Intel
32 CORE I7-4910MQ CPU @ 2.90GHZ 8 11,741 93,928 Intel
33 RYZEN 7 1700 EIGHT-CORE 16 5,206 83,296 AMD
34 CORE I7-8550U CPU @ 1.80GHZ 8 8,872 70,976 Intel
35 CORE I7-4790K CPU @ 4.00GHZ 8 8,237 65,896 Intel
36 XEON CPU E3-1270 V5 @ 3.60GHZ 8 8,081 64,648 Intel
37 CORE I7-8705G CPU @ 3.10GHZ 8 8,036 64,288 Intel
38 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,668 64,032 Intel
39 XEON W-2123 CPU @ 3.60GHZ 8 7,872 62,976 Intel
40 RYZEN 3 3200G 4 15,608 62,432 AMD
41 CORE I7-6800K CPU @ 3.40GHZ 12 4,896 58,752 Intel
42 CORE I7-9850H CPU @ 2.60GHZ 12 4,800 57,600 Intel
43 CORE I7-4930K CPU @ 3.40GHZ 12 4,793 57,516 Intel
44 RYZEN 5 2600 SIX-CORE 12 4,789 57,468 AMD
45 CORE I5-7600 CPU @ 3.50GHZ 4 13,716 54,864 Intel
46 CORE I7-6700 CPU @ 3.40GHZ 8 6,803 54,424 Intel
47 XEON E-2124G CPU @ 3.40GHZ 4 12,840 51,360 Intel
48 CORE I5-6500 CPU @ 3.20GHZ 4 12,759 51,036 Intel
49 CORE I3-6100 CPU @ 3.70GHZ 4 11,014 44,056 Intel
50 CORE I5-7400 CPU @ 3.00GHZ 4 10,782 43,128 Intel
51 CORE I3-8100 CPU @ 3.60GHZ 4 10,242 40,968 Intel
52 CORE I7-3770 CPU @ 3.40GHZ 8 4,948 39,584 Intel
53 CORE I7-8665U CPU @ 1.90GHZ 8 4,930 39,440 Intel
54 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 4,902 39,216 Intel
55 RYZEN 5 1400 QUAD-CORE 8 4,712 37,696 AMD
56 CORE I7-1068NG7 CPU @ 2.30GHZ 8 4,702 37,616 Intel
57 CORE I7-8565U CPU @ 1.80GHZ 8 4,489 35,912 Intel
58 XEON CPU E3-1230 V2 @ 3.30GHZ 8 4,084 32,672 Intel
59 CORE I7-6700K CPU @ 4.00GHZ 8 3,534 28,272 Intel
60 CORE I7-6700HQ CPU @ 2.60GHZ 8 3,447 27,576 Intel
61 PHENOM II X6 1090T 6 3,974 23,844 AMD
62 FX-8350 EIGHT-CORE 8 2,890 23,120 AMD
63 CORE I5-6200U CPU @ 2.30GHZ 4 5,486 21,944 Intel
64 CORE I7-2760QM CPU @ 2.40GHZ 8 2,525 20,200 Intel
65 CORE I3-7100 CPU @ 3.90GHZ 4 4,571 18,284 Intel
66 FX-8320 EIGHT-CORE 8 1,838 14,704 AMD
67 RYZEN 7 4700U 8 1,724 13,792 AMD
68 PENTIUM(R) SILVER N5000 CPU @ 1.10GHZ 4 2,984 11,936 Intel
69 PHENOM II X4 965 4 2,910 11,640 AMD
70 FX-8300 EIGHT-CORE 8 1,335 10,680 AMD
71 CORE I3-6006U CPU @ 2.00GHZ 4 2,498 9,992 Intel
72 CORE I5-2540M CPU @ 2.60GHZ 4 2,199 8,796 Intel
73 CELERON(R) CPU G550 @ 2.60GHZ 2 1,518 3,036 Intel
74 CORE2 QUAD CPU Q6600 @ 2.40GHZ 4 670 2,680 Intel
75 A8-6410 APU 4 495 1,980 AMD
76 CELERON(R) CPU N3350 @ 1.10GHZ 2 134 268 Intel