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PROJECT #16947 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 04 August 2021 19:04:08

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 04 August 2021 19:04:08

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 25,460 814,720 AMD
2 RYZEN 9 5950X 16-CORE 32 17,840 570,880 AMD
3 CORE I9-9980XE CPU @ 3.00GHZ 36 12,659 455,724 Intel
4 RYZEN 7 5800X 8-CORE 16 27,595 441,520 AMD
5 RYZEN 9 3900XT 12-CORE 24 15,974 383,376 AMD
6 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,685 368,880 AMD
7 EPYC 7302 16-CORE 64 5,473 350,272 AMD
8 RYZEN 9 5900X 12-CORE 24 14,508 348,192 AMD
9 RYZEN 9 3900 12-CORE 24 14,365 344,760 AMD
10 CORE I9-10900KF CPU @ 3.70GHZ 20 16,061 321,220 Intel
11 CORE I9-9900KF CPU @ 3.60GHZ 16 19,627 314,032 Intel
12 RYZEN 9 3900X 12-CORE 24 12,863 308,712 AMD
13 CORE I9-9900K CPU @ 3.60GHZ 16 17,603 281,648 Intel
14 XEON CPU E5-2690 V4 @ 2.60GHZ 28 9,857 275,996 Intel
15 CORE I9-10900X CPU @ 3.70GHZ 20 13,565 271,300 Intel
16 11TH GEN CORE I9-11900K @ 3.50GHZ 16 16,698 267,168 Intel
17 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,825 259,800 Intel
18 CORE I7-10700F CPU @ 2.90GHZ 16 15,275 244,400 Intel
19 RYZEN 5 5600X 6-CORE 12 20,336 244,032 AMD
20 11TH GEN CORE I7-11700K @ 3.60GHZ 16 15,237 243,792 Intel
21 RYZEN THREADRIPPER 3960X 24-CORE 48 4,911 235,728 AMD
22 11TH GEN CORE I5-11400 @ 2.60GHZ 12 19,636 235,632 Intel
23 CORE I7-10700K CPU @ 3.80GHZ 16 13,806 220,896 Intel
24 CORE I9-7920X CPU @ 2.90GHZ 24 9,051 217,224 Intel
25 RYZEN 7 3800X 8-CORE 16 13,222 211,552 AMD
26 CORE I7-9700K CPU @ 3.60GHZ 8 25,920 207,360 Intel
27 RYZEN 7 3700X 8-CORE 16 12,654 202,464 AMD
28 RYZEN 5 3600 6-CORE 12 16,143 193,716 AMD
29 CORE I7-9700 CPU @ 3.00GHZ 8 23,906 191,248 Intel
30 RYZEN 5 3500 6-CORE 6 27,557 165,342 AMD
31 RYZEN 5 2600X SIX-CORE 12 13,114 157,368 AMD
32 RYZEN 7 2700X EIGHT-CORE 16 9,538 152,608 AMD
33 CORE I7-8700 CPU @ 3.20GHZ 12 11,942 143,304 Intel
34 CORE I7-9850H CPU @ 2.60GHZ 12 11,404 136,848 Intel
35 CORE I5-10400 CPU @ 2.90GHZ 12 10,900 130,800 Intel
36 RYZEN 3 3100 4-CORE 8 16,025 128,200 AMD
37 RYZEN 7 1700 EIGHT-CORE 16 7,998 127,968 AMD
38 CORE I7-10700 CPU @ 2.90GHZ 16 7,926 126,816 Intel
39 CORE I5-9400F CPU @ 2.90GHZ 6 20,953 125,718 Intel
40 CORE I7-9700T CPU @ 2.00GHZ 8 15,578 124,624 Intel
41 RYZEN THREADRIPPER 1920X 12-CORE 24 5,171 124,104 AMD
42 RYZEN THREADRIPPER 2950X 16-CORE 32 3,798 121,536 AMD
43 CORE I5-10400F CPU @ 2.90GHZ 12 9,667 116,004 Intel
44 CORE I7-8700B CPU @ 3.20GHZ 12 9,642 115,704 Intel
45 CORE I7-6700K CPU @ 4.00GHZ 8 14,197 113,576 Intel
46 CORE I7-10870H CPU @ 2.20GHZ 16 7,031 112,496 Intel
47 RYZEN 5 2600 SIX-CORE 12 8,105 97,260 AMD
48 XEON CPU E5-2620 V2 @ 2.10GHZ 24 3,826 91,824 Intel
49 CORE I7-8705G CPU @ 3.10GHZ 8 11,357 90,856 Intel
50 CORE I7-4790K CPU @ 4.00GHZ 8 10,446 83,568 Intel
51 CORE I7-10750H CPU @ 2.60GHZ 12 6,192 74,304 Intel
52 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,141 73,128 Intel
53 CORE I7-6700 CPU @ 3.40GHZ 8 9,136 73,088 Intel
54 XEON W-10855M CPU @ 2.80GHZ 12 5,624 67,488 Intel
55 CORE I5-8300H CPU @ 2.30GHZ 8 8,355 66,840 Intel
56 EPYC 7571 32-CORE 64 1,033 66,112 AMD
57 CORE I7-8565U CPU @ 1.80GHZ 8 7,151 57,208 Intel
58 CORE I7-8550U CPU @ 1.80GHZ 8 6,697 53,576 Intel
59 CORE I7-3770 CPU @ 3.40GHZ 8 6,108 48,864 Intel
60 XEON CPU E3-1230 V2 @ 3.30GHZ 8 5,979 47,832 Intel
61 XEON CPU E5-2678 V3 @ 2.50GHZ 6 7,505 45,030 Intel
62 XEON SILVER 4116 CPU @ 2.10GHZ 24 1,858 44,592 Intel
63 CORE I5-8400 CPU @ 2.80GHZ 6 6,534 39,204 Intel
64 XEON CPU E5-2650 0 @ 2.00GHZ 16 2,432 38,912 Intel
65 CORE I7-2600 CPU @ 3.40GHZ 8 3,621 28,968 Intel
66 CORE I7-4770K CPU @ 3.50GHZ 8 3,559 28,472 Intel
67 FX-8320 EIGHT-CORE 8 2,002 16,016 AMD