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PROJECT #16948 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 20 March 2023 06:14:56

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 20 March 2023 06:14:56

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 24,712 790,784 AMD
2 RYZEN 9 5950X 16-CORE 32 15,641 500,512 AMD
3 EPYC 7302 16-CORE 64 7,034 450,176 AMD
4 RYZEN 7 5800X 8-CORE 16 26,832 429,312 AMD
5 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,048 386,304 AMD
6 RYZEN 9 5900X 12-CORE 24 15,095 362,280 AMD
7 CORE I9-7920X CPU @ 2.90GHZ 24 14,984 359,616 Intel
8 RYZEN 9 3900XT 12-CORE 24 14,288 342,912 AMD
9 RYZEN 9 3900 12-CORE 24 14,243 341,832 AMD
10 CORE I9-9900KS CPU @ 4.00GHZ 16 19,779 316,464 Intel
11 RYZEN 9 3900X 12-CORE 24 12,913 309,912 AMD
12 EPYC 7302P 16-CORE 32 9,344 299,008 AMD
13 11TH GEN CORE I7-11700K @ 3.60GHZ 16 18,602 297,632 Intel
14 CORE I7-10875H CPU @ 2.30GHZ 16 18,198 291,168 Intel
15 XEON CPU E5-2690 V4 @ 2.60GHZ 28 9,386 262,808 Intel
16 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,838 260,112 Intel
17 RYZEN 5 5600X 6-CORE 12 21,183 254,196 AMD
18 RYZEN THREADRIPPER 3960X 24-CORE 48 5,087 244,176 AMD
19 RYZEN 7 3700X 8-CORE 16 14,686 234,976 AMD
20 CORE I9-10900X CPU @ 3.70GHZ 20 11,654 233,080 Intel
21 11TH GEN CORE I5-11600K @ 3.90GHZ 12 18,596 223,152 Intel
22 CORE I7-10700F CPU @ 2.90GHZ 16 13,759 220,144 Intel
23 RYZEN 7 3800X 8-CORE 16 12,794 204,704 AMD
24 RYZEN 5 3600X 6-CORE 12 16,969 203,628 AMD
25 CORE I7-9700 CPU @ 3.00GHZ 8 24,286 194,288 Intel
26 RYZEN 7 4800H 16 11,299 180,784 AMD
27 CORE I7-8700 CPU @ 3.20GHZ 12 14,893 178,716 Intel
28 CORE I7-10700 CPU @ 2.90GHZ 16 10,779 172,464 Intel
29 RYZEN 7 2700X EIGHT-CORE 16 10,642 170,272 AMD
30 CORE I7-9700K CPU @ 3.60GHZ 8 21,259 170,072 Intel
31 11TH GEN CORE I7-11700F @ 2.50GHZ 16 10,458 167,328 Intel
32 CORE I5-10400F CPU @ 2.90GHZ 12 13,887 166,644 Intel
33 RYZEN THREADRIPPER 1920X 12-CORE 24 6,742 161,808 AMD
34 RYZEN 5 3600 6-CORE 12 13,402 160,824 AMD
35 CORE I5-10400 CPU @ 2.90GHZ 12 12,449 149,388 Intel
36 CORE I7-10700K CPU @ 3.80GHZ 16 9,212 147,392 Intel
37 CORE I7-10870H CPU @ 2.20GHZ 16 9,082 145,312 Intel
38 RYZEN 3 3100 4-CORE 8 16,229 129,832 AMD
39 RYZEN 5 3600XT 6-CORE 12 10,808 129,696 AMD
40 CORE I5-9400F CPU @ 2.90GHZ 6 21,158 126,948 Intel
41 RYZEN 7 1700 EIGHT-CORE 16 7,805 124,880 AMD
42 CORE I7-6700K CPU @ 4.00GHZ 8 14,842 118,736 Intel
43 RYZEN 5 1600 SIX-CORE 12 9,413 112,956 AMD
44 RYZEN 5 2600X SIX-CORE 12 9,054 108,648 AMD
45 XEON CPU E5-2620 V2 @ 2.10GHZ 24 4,242 101,808 Intel
46 RYZEN 5 2600 SIX-CORE 12 8,204 98,448 AMD
47 RYZEN 5 4600HS 12 7,620 91,440 AMD
48 11TH GEN CORE I5-11400 @ 2.60GHZ 12 7,403 88,836 Intel
49 CORE I5-10300H CPU @ 2.50GHZ 8 10,216 81,728 Intel
50 CORE I7-7700K CPU @ 4.20GHZ 8 10,110 80,880 Intel
51 CORE I7-8705G CPU @ 3.10GHZ 8 10,065 80,520 Intel
52 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,656 77,248 Intel
53 XEON CPU X5660 @ 2.80GHZ 24 3,079 73,896 Intel
54 RYZEN 5 3500X 6-CORE 6 11,896 71,376 AMD
55 RYZEN 7 2700 EIGHT-CORE 16 4,452 71,232 AMD
56 XEON W-10855M CPU @ 2.80GHZ 12 5,861 70,332 Intel
57 CORE I5-8300H CPU @ 2.30GHZ 8 8,596 68,768 Intel
58 RYZEN 7 4700U 8 8,233 65,864 AMD
59 CORE I7-4790T CPU @ 2.70GHZ 8 7,338 58,704 Intel
60 CORE I5-9300H CPU @ 2.40GHZ 8 7,211 57,688 Intel
61 CORE I7-8550U CPU @ 1.80GHZ 8 7,088 56,704 Intel
62 XEON CPU X5670 @ 2.93GHZ 12 4,207 50,484 Intel
63 CORE I7-3840QM CPU @ 2.80GHZ 8 6,143 49,144 Intel
64 CORE I7-3770 CPU @ 3.40GHZ 8 6,049 48,392 Intel
65 XEON CPU E3-1241 V3 @ 3.50GHZ 8 4,750 38,000 Intel
66 CORE I7-3610QM CPU @ 2.30GHZ 8 3,225 25,800 Intel