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PROJECT #16944 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 23 July 2021 12:13:40

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Friday, 23 July 2021 12:13:40

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 26,677 853,664 AMD
2 RYZEN 9 5950X 16-CORE 32 18,763 600,416 AMD
3 XEON W-2175 CPU @ 2.50GHZ 28 21,268 595,504 Intel
4 RYZEN 9 5900X 12-CORE 24 21,020 504,480 AMD
5 RYZEN THREADRIPPER 3970X 32-CORE 64 6,621 423,744 AMD
6 RYZEN 7 5800X 8-CORE 16 24,537 392,592 AMD
7 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,963 382,224 AMD
8 CORE I9-10900K CPU @ 3.70GHZ 20 18,443 368,860 Intel
9 XEON PLATINUM 8124M CPU @ 3.00GHZ 36 9,477 341,172 Intel
10 CORE I9-9900KF CPU @ 3.60GHZ 16 19,444 311,104 Intel
11 RYZEN 9 3900X 12-CORE 24 12,528 300,672 AMD
12 EPYC 7302P 16-CORE 32 8,773 280,736 AMD
13 XEON CPU E5-2667 V2 @ 3.30GHZ 32 8,726 279,232 Intel
14 RYZEN 5 5600X 6-CORE 12 21,869 262,428 AMD
15 RYZEN 7 3700X 8-CORE 16 14,345 229,520 AMD
16 CORE I9-7920X CPU @ 2.90GHZ 24 9,555 229,320 Intel
17 CORE I7-10700K CPU @ 3.80GHZ 16 13,616 217,856 Intel
18 RYZEN 7 3800X 8-CORE 16 13,260 212,160 AMD
19 RYZEN 7 4800H 16 12,939 207,024 AMD
20 RYZEN 5 3600X 6-CORE 12 17,010 204,120 AMD
21 CORE I7-9700KF CPU @ 3.60GHZ 8 24,841 198,728 Intel
22 CORE I7-9700K CPU @ 3.60GHZ 8 24,589 196,712 Intel
23 CORE I7-9700 CPU @ 3.00GHZ 8 24,416 195,328 Intel
24 XEON CPU E5-2660 0 @ 2.20GHZ 32 6,020 192,640 Intel
25 RYZEN 5 3600 6-CORE 12 15,703 188,436 AMD
26 RYZEN THREADRIPPER 2950X 16-CORE 32 5,583 178,656 AMD
27 RYZEN 5 PRO 4650G 12 14,592 175,104 AMD
28 CORE I7-8700K CPU @ 3.70GHZ 12 13,850 166,200 Intel
29 XEON CPU E5-2690 V2 @ 3.00GHZ 20 7,804 156,080 Intel
30 RYZEN 7 2700X EIGHT-CORE 16 9,635 154,160 AMD
31 RYZEN 5 3500 6-CORE 6 23,501 141,006 AMD
32 RYZEN 7 1700X EIGHT-CORE 16 8,606 137,696 AMD
33 RYZEN THREADRIPPER 1920X 12-CORE 24 5,661 135,864 AMD
34 CORE I5-9400F CPU @ 2.90GHZ 6 20,990 125,940 Intel
35 RYZEN 7 1700 EIGHT-CORE 16 7,751 124,016 AMD
36 CORE I5-10400F CPU @ 2.90GHZ 12 9,995 119,940 Intel
37 RYZEN 5 1600 SIX-CORE 12 9,571 114,852 AMD
38 RYZEN 5 2600 SIX-CORE 12 8,824 105,888 AMD
39 CORE I7-2600 CPU @ 3.40GHZ 8 13,058 104,464 Intel
40 RYZEN 5 2600X SIX-CORE 12 8,163 97,956 AMD
41 CORE I7-10700F CPU @ 2.90GHZ 16 6,110 97,760 Intel
42 XEON CPU E5-2620 V2 @ 2.10GHZ 24 3,982 95,568 Intel
43 CORE I7-8705G CPU @ 3.10GHZ 8 10,041 80,328 Intel
44 CORE I7-6700K CPU @ 4.00GHZ 8 9,814 78,512 Intel
45 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,778 78,224 Intel
46 CORE I7-8559U CPU @ 2.70GHZ 8 9,438 75,504 Intel
47 CORE I7-4770 CPU @ 3.40GHZ 8 8,515 68,120 Intel
48 XEON CPU E5-2690 V3 @ 2.60GHZ 12 5,520 66,240 Intel
49 CORE I7-4910MQ CPU @ 2.90GHZ 8 8,065 64,520 Intel
50 CORE I7-6800K CPU @ 3.40GHZ 12 5,289 63,468 Intel
51 CORE I7-8550U CPU @ 1.80GHZ 8 7,005 56,040 Intel
52 CORE I7-6700 CPU @ 3.40GHZ 8 6,655 53,240 Intel
53 CORE I7-3840QM CPU @ 2.80GHZ 8 6,303 50,424 Intel
54 CORE I7-8565U CPU @ 1.80GHZ 8 6,287 50,296 Intel
55 CORE I7-3770 CPU @ 3.40GHZ 8 6,247 49,976 Intel
56 XEON CPU E5-2650 0 @ 2.00GHZ 16 3,011 48,176 Intel
57 CORE I7-4770K CPU @ 3.50GHZ 8 4,571 36,568 Intel
58 XEON SILVER 4116 CPU @ 2.10GHZ 24 1,354 32,496 Intel
59 PHENOM II X6 1090T 6 5,248 31,488 AMD
60 CORE I7-1065G7 CPU @ 1.30GHZ 8 3,226 25,808 Intel
61 CORE I7-1068NG7 CPU @ 2.30GHZ 8 2,767 22,136 Intel
62 FX-8320 EIGHT-CORE 8 2,214 17,712 AMD