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PROJECT #16950 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 31 January 2023 00:15:03

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 31 January 2023 00:15:03

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 29,864 955,648 AMD
2 RYZEN 9 5950X 16-CORE 32 17,445 558,240 AMD
3 CORE I9-9980XE CPU @ 3.00GHZ 36 12,500 450,000 Intel
4 RYZEN 7 5800X 8-CORE 16 26,748 427,968 AMD
5 RYZEN 9 5900X 12-CORE 24 16,659 399,816 AMD
6 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,264 396,672 AMD
7 RYZEN 9 3900XT 12-CORE 24 16,253 390,072 AMD
8 11TH GEN CORE I9-11900K @ 3.50GHZ 16 23,014 368,224 Intel
9 RYZEN 9 3900 12-CORE 24 14,123 338,952 AMD
10 CORE I9-10900KF CPU @ 3.70GHZ 20 16,401 328,020 Intel
11 RYZEN 9 3900X 12-CORE 24 13,338 320,112 AMD
12 XEON CPU E5-2680 V3 @ 2.50GHZ 24 13,132 315,168 Intel
13 CORE I9-10900X CPU @ 3.70GHZ 20 15,130 302,600 Intel
14 CORE I7-10875H CPU @ 2.30GHZ 16 18,311 292,976 Intel
15 CORE I9-7920X CPU @ 2.90GHZ 24 12,084 290,016 Intel
16 XEON CPU E5-2667 V2 @ 3.30GHZ 32 8,840 282,880 Intel
17 11TH GEN CORE I7-11700K @ 3.60GHZ 16 17,287 276,592 Intel
18 XEON CPU E5-2680 V4 @ 2.40GHZ 28 9,520 266,560 Intel
19 RYZEN 5 5600X 6-CORE 12 21,533 258,396 AMD
20 XEON CPU E5-2690 V4 @ 2.60GHZ 28 9,141 255,948 Intel
21 RYZEN 7 3700X 8-CORE 16 15,502 248,032 AMD
22 RYZEN 7 3800X 8-CORE 16 15,038 240,608 AMD
23 CORE I7-9700K CPU @ 3.60GHZ 8 29,187 233,496 Intel
24 RYZEN THREADRIPPER 3960X 24-CORE 48 4,813 231,024 AMD
25 CORE I7-1068NG7 CPU @ 2.30GHZ 8 26,708 213,664 Intel
26 RYZEN 5 3600X 6-CORE 12 17,227 206,724 AMD
27 CORE I7-10700K CPU @ 3.80GHZ 16 12,724 203,584 Intel
28 RYZEN THREADRIPPER 2950X 16-CORE 32 6,334 202,688 AMD
29 XEON CPU E5-2660 0 @ 2.20GHZ 32 6,042 193,344 Intel
30 RYZEN 5 3600 6-CORE 12 15,354 184,248 AMD
31 RYZEN 7 4800H 16 11,512 184,192 AMD
32 CORE I7-8700 CPU @ 3.20GHZ 12 15,285 183,420 Intel
33 RYZEN 5 PRO 4650G 12 14,756 177,072 AMD
34 11TH GEN CORE I7-11700F @ 2.50GHZ 16 10,872 173,952 Intel
35 RYZEN 5 3500 6-CORE 6 28,108 168,648 AMD
36 RYZEN 7 2700X EIGHT-CORE 16 10,097 161,552 AMD
37 RYZEN 5 5600H 12 13,256 159,072 AMD
38 RYZEN THREADRIPPER 1920X 12-CORE 24 6,129 147,096 AMD
39 RYZEN 7 1700 EIGHT-CORE 16 8,954 143,264 AMD
40 CORE I7-10700 CPU @ 2.90GHZ 16 8,941 143,056 Intel
41 CORE I7-10870H CPU @ 2.20GHZ 16 8,718 139,488 Intel
42 XEON CPU E5-2690 V2 @ 3.00GHZ 20 6,564 131,280 Intel
43 CORE I7-9700T CPU @ 2.00GHZ 8 16,316 130,528 Intel
44 CORE I5-9400F CPU @ 2.90GHZ 6 20,841 125,046 Intel
45 11TH GEN CORE I5-11400 @ 2.60GHZ 12 9,695 116,340 Intel
46 CORE I5-10400F CPU @ 2.90GHZ 12 9,628 115,536 Intel
47 EPYC 7571 32-CORE 64 1,772 113,408 AMD
48 RYZEN 5 1600 SIX-CORE 12 8,738 104,856 AMD
49 XEON CPU E5-2620 V2 @ 2.10GHZ 24 4,079 97,896 Intel
50 RYZEN 5 3500U 8 12,018 96,144 AMD
51 RYZEN 5 2600 SIX-CORE 12 7,761 93,132 AMD
52 CORE I5-8400 CPU @ 2.80GHZ 6 14,359 86,154 Intel
53 CORE I7-6700K CPU @ 4.00GHZ 8 10,700 85,600 Intel
54 CORE I7-3610QM CPU @ 2.30GHZ 8 9,368 74,944 Intel
55 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 8,956 71,648 Intel
56 XEON CPU E5-2690 V3 @ 2.60GHZ 12 5,596 67,152 Intel
57 CORE I7-3840QM CPU @ 2.80GHZ 8 8,271 66,168 Intel
58 CORE I7-8550U CPU @ 1.80GHZ 8 7,211 57,688 Intel
59 XEON W-10855M CPU @ 2.80GHZ 12 4,289 51,468 Intel
60 CORE I7-3770 CPU @ 3.40GHZ 8 6,162 49,296 Intel
61 XEON CPU E5-2678 V3 @ 2.50GHZ 6 7,482 44,892 Intel
62 CORE I7-8565U CPU @ 1.80GHZ 8 5,445 43,560 Intel
63 CORE I7-4770K CPU @ 3.50GHZ 8 3,754 30,032 Intel
64 FX-8320 EIGHT-CORE 8 2,381 19,048 AMD