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PROJECT #16952 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 31 January 2023 00:15:03

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 31 January 2023 00:15:03

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 31,162 997,184 AMD
2 RYZEN 9 5950X 16-CORE 32 17,024 544,768 AMD
3 CORE I9-9980XE CPU @ 3.00GHZ 36 11,928 429,408 Intel
4 RYZEN 7 5800X 8-CORE 16 25,957 415,312 AMD
5 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,281 397,488 AMD
6 RYZEN 9 3900XT 12-CORE 24 15,642 375,408 AMD
7 RYZEN 9 5900X 12-CORE 24 15,493 371,832 AMD
8 RYZEN 9 3900 12-CORE 24 14,630 351,120 AMD
9 CORE I9-10900KF CPU @ 3.70GHZ 20 15,934 318,680 Intel
10 CORE I9-7920X CPU @ 2.90GHZ 24 13,023 312,552 Intel
11 11TH GEN CORE I7-11700K @ 3.60GHZ 16 19,245 307,920 Intel
12 CORE I7-10875H CPU @ 2.30GHZ 16 18,515 296,240 Intel
13 RYZEN 9 3900X 12-CORE 24 12,161 291,864 AMD
14 RYZEN 5 5600X 6-CORE 12 23,169 278,028 AMD
15 CORE I9-10900X CPU @ 3.70GHZ 20 13,047 260,940 Intel
16 11TH GEN CORE I9-11900K @ 3.50GHZ 16 16,188 259,008 Intel
17 XEON CPU E5-2680 V4 @ 2.40GHZ 28 9,059 253,652 Intel
18 XEON CPU E5-2690 V4 @ 2.60GHZ 28 8,767 245,476 Intel
19 CORE I7-9700K CPU @ 3.60GHZ 8 28,829 230,632 Intel
20 RYZEN THREADRIPPER 3960X 24-CORE 48 4,681 224,688 AMD
21 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,354 224,496 Intel
22 11TH GEN CORE I5-11600K @ 3.90GHZ 12 18,288 219,456 Intel
23 RYZEN 7 3700X 8-CORE 16 13,063 209,008 AMD
24 RYZEN 5 3600X 6-CORE 12 16,381 196,572 AMD
25 RYZEN 7 3800X 8-CORE 16 12,182 194,912 AMD
26 XEON CPU E5-2660 0 @ 2.20GHZ 32 5,827 186,464 Intel
27 XEON CPU E5-2690 V2 @ 3.00GHZ 20 9,218 184,360 Intel
28 11TH GEN CORE I9-11900F @ 2.50GHZ 16 11,302 180,832 Intel
29 RYZEN 5 3600 6-CORE 12 14,705 176,460 AMD
30 CORE I7-8700 CPU @ 3.20GHZ 12 13,634 163,608 Intel
31 RYZEN 7 4800H 16 10,127 162,032 AMD
32 RYZEN 5 3500 6-CORE 6 25,750 154,500 AMD
33 CORE I5-10400 CPU @ 2.90GHZ 12 12,827 153,924 Intel
34 CORE I7-10700 CPU @ 2.90GHZ 16 9,167 146,672 Intel
35 CORE I5-10400F CPU @ 2.90GHZ 12 11,554 138,648 Intel
36 RYZEN 7 2700X EIGHT-CORE 16 8,506 136,096 AMD
37 CORE I7-10870H CPU @ 2.20GHZ 16 8,464 135,424 Intel
38 CORE I5-9400F CPU @ 2.90GHZ 6 20,982 125,892 Intel
39 RYZEN 3 3100 4-CORE 8 15,646 125,168 AMD
40 RYZEN 7 1700 EIGHT-CORE 16 7,474 119,584 AMD
41 RYZEN THREADRIPPER 1920X 12-CORE 24 4,707 112,968 AMD
42 RYZEN 5 2600X SIX-CORE 12 8,858 106,296 AMD
43 RYZEN 5 1600 SIX-CORE 12 8,052 96,624 AMD
44 RYZEN 5 2600 SIX-CORE 12 7,641 91,692 AMD
45 CORE I7-8705G CPU @ 3.10GHZ 8 10,254 82,032 Intel
46 CORE I5-8400 CPU @ 2.80GHZ 6 13,204 79,224 Intel
47 CORE I5-10300H CPU @ 2.50GHZ 8 9,401 75,208 Intel
48 XEON W-10855M CPU @ 2.80GHZ 12 6,025 72,300 Intel
49 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 8,841 70,728 Intel
50 CORE I5-8300H CPU @ 2.30GHZ 8 8,503 68,024 Intel
51 CORE I7-6700K CPU @ 4.00GHZ 8 8,438 67,504 Intel
52 XEON CPU E5-2650 0 @ 2.00GHZ 16 3,595 57,520 Intel
53 CORE I7-2600K CPU @ 3.40GHZ 8 7,124 56,992 Intel
54 XEON CPU X5670 @ 2.93GHZ 12 4,284 51,408 Intel
55 CORE I7-3770 CPU @ 3.40GHZ 8 5,880 47,040 Intel
56 XEON CPU E3-1230 V2 @ 3.30GHZ 8 5,793 46,344 Intel
57 CORE I7-8565U CPU @ 1.80GHZ 8 5,331 42,648 Intel
58 CORE I7-6700 CPU @ 3.40GHZ 8 4,827 38,616 Intel
59 RYZEN 7 1800X EIGHT-CORE 16 1,977 31,632 AMD