PROJECT #16945 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 03 December 2021 04:36:10

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Friday, 03 December 2021 04:36:10

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 25,443 814,176 AMD
2 RYZEN 9 5950X 16-CORE 32 16,849 539,168 AMD
3 EPYC 7302 16-CORE 64 7,418 474,752 AMD
4 CORE I9-9980XE CPU @ 3.00GHZ 36 13,104 471,744 Intel
5 RYZEN 9 5900X 12-CORE 24 19,364 464,736 AMD
6 RYZEN 7 5800X 8-CORE 16 26,415 422,640 AMD
7 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,500 408,000 AMD
8 RYZEN 9 3900XT 12-CORE 24 16,363 392,712 AMD
9 RYZEN 9 3900 12-CORE 24 15,008 360,192 AMD
10 XEON PLATINUM 8124M CPU @ 3.00GHZ 36 9,636 346,896 Intel
11 11TH GEN CORE I7-11700K @ 3.60GHZ 16 20,704 331,264 Intel
12 RYZEN 9 3900X 12-CORE 24 12,346 296,304 AMD
13 RYZEN 5 5600X 6-CORE 12 23,221 278,652 AMD
14 CORE I9-10900X CPU @ 3.70GHZ 20 13,576 271,520 Intel
15 XEON CPU E5-2690 V4 @ 2.60GHZ 28 9,345 261,660 Intel
16 11TH GEN CORE I9-11900K @ 3.50GHZ 16 15,630 250,080 Intel
17 RYZEN THREADRIPPER 3960X 24-CORE 48 5,097 244,656 AMD
18 RYZEN 7 3700X 8-CORE 16 14,227 227,632 AMD
19 RYZEN 5 3600X 6-CORE 12 17,613 211,356 AMD
20 CORE I7-9700K CPU @ 3.60GHZ 8 25,648 205,184 Intel
21 CORE I7-9700 CPU @ 3.00GHZ 8 25,525 204,200 Intel
22 XEON CPU E5-2680 V3 @ 2.50GHZ 24 8,489 203,736 Intel
23 CORE I7-10700K CPU @ 3.80GHZ 16 12,436 198,976 Intel
24 RYZEN 7 3800X 8-CORE 16 12,095 193,520 AMD
25 CORE I9-7920X CPU @ 2.90GHZ 24 7,907 189,768 Intel
26 RYZEN 5 3600 6-CORE 12 15,549 186,588 AMD
27 RYZEN 5 PRO 4650G 12 15,039 180,468 AMD
28 RYZEN 5 2600X SIX-CORE 12 14,403 172,836 AMD
29 CORE I7-10700 CPU @ 2.90GHZ 16 10,561 168,976 Intel
30 XEON CPU E5-2690 V2 @ 3.00GHZ 20 8,398 167,960 Intel
31 RYZEN 7 2700X EIGHT-CORE 16 9,558 152,928 AMD
32 CORE I5-10400F CPU @ 2.90GHZ 12 11,613 139,356 Intel
33 CORE I5-9400F CPU @ 2.90GHZ 6 22,737 136,422 Intel
34 RYZEN THREADRIPPER 1920X 12-CORE 24 5,472 131,328 AMD
35 RYZEN 7 1700 EIGHT-CORE 16 7,988 127,808 AMD
36 RYZEN 3 3100 4-CORE 8 15,540 124,320 AMD
37 CORE I7-6700K CPU @ 4.00GHZ 8 14,792 118,336 Intel
38 CORE I5-8400 CPU @ 2.80GHZ 6 16,475 98,850 Intel
39 RYZEN 5 2600 SIX-CORE 12 8,104 97,248 AMD
40 XEON CPU E5-2620 V2 @ 2.10GHZ 24 4,017 96,408 Intel
41 CORE I7-8705G CPU @ 3.10GHZ 8 11,516 92,128 Intel
42 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,253 74,024 Intel
43 CORE I7-1068NG7 CPU @ 2.30GHZ 8 8,900 71,200 Intel
44 XEON W-10855M CPU @ 2.80GHZ 12 5,855 70,260 Intel
45 XEON CPU E5-2690 V3 @ 2.60GHZ 12 5,711 68,532 Intel
46 CORE I7-8550U CPU @ 1.80GHZ 8 7,194 57,552 Intel
47 CORE I7-3770 CPU @ 3.40GHZ 8 6,309 50,472 Intel
48 CORE I7-2600 CPU @ 3.40GHZ 8 3,637 29,096 Intel