PROJECT #16945 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 15 April 2021 07:31:06

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 15 April 2021 07:31:06

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 21,787 697,184 AMD
2 RYZEN 9 5950X 16-CORE 32 15,942 510,144 AMD
3 RYZEN 9 5900X 12-CORE 24 20,731 497,544 AMD
4 EPYC 7302 16-CORE 64 7,418 474,752 AMD
5 CORE I9-9980XE CPU @ 3.00GHZ 36 13,104 471,744 Intel
6 RYZEN 7 5800X 8-CORE 16 27,364 437,824 AMD
7 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,492 407,616 AMD
8 RYZEN 9 3900 12-CORE 24 14,603 350,472 AMD
9 XEON PLATINUM 8124M CPU @ 3.00GHZ 36 9,636 346,896 Intel
10 RYZEN 9 3900X 12-CORE 24 12,346 296,304 AMD
11 RYZEN 5 5600X 6-CORE 12 20,901 250,812 AMD
12 CORE I9-10900X CPU @ 3.70GHZ 20 11,499 229,980 Intel
13 RYZEN 7 3700X 8-CORE 16 14,227 227,632 AMD
14 RYZEN 5 3600X 6-CORE 12 17,613 211,356 AMD
15 CORE I7-9700K CPU @ 3.60GHZ 8 26,119 208,952 Intel
16 CORE I7-9700 CPU @ 3.00GHZ 8 25,525 204,200 Intel
17 RYZEN 5 3600 6-CORE 12 16,495 197,940 AMD
18 XEON CPU E5-2690 V2 @ 3.00GHZ 20 9,803 196,060 Intel
19 CORE I9-7920X CPU @ 2.90GHZ 24 7,907 189,768 Intel
20 RYZEN 7 3800X 8-CORE 16 11,431 182,896 AMD
21 RYZEN 5 PRO 4650G 12 15,039 180,468 AMD
22 RYZEN 7 2700X EIGHT-CORE 16 8,922 142,752 AMD
23 CORE I5-9400F CPU @ 2.90GHZ 6 22,737 136,422 Intel
24 RYZEN 7 1700 EIGHT-CORE 16 7,988 127,808 AMD
25 CORE I5-10400F CPU @ 2.90GHZ 12 10,599 127,188 Intel
26 RYZEN THREADRIPPER 1920X 12-CORE 24 5,118 122,832 AMD
27 RYZEN 5 2600X SIX-CORE 12 9,886 118,632 AMD
28 CORE I7-6700K CPU @ 4.00GHZ 8 13,045 104,360 Intel
29 RYZEN 3 3100 4-CORE 8 12,996 103,968 AMD
30 RYZEN 5 2600 SIX-CORE 12 8,104 97,248 AMD
31 XEON CPU E5-2620 V2 @ 2.10GHZ 24 4,017 96,408 Intel
32 CORE I7-8705G CPU @ 3.10GHZ 8 11,516 92,128 Intel
33 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 10,326 82,608 Intel
34 CORE I7-1068NG7 CPU @ 2.30GHZ 8 8,900 71,200 Intel
35 XEON CPU E5-2690 V3 @ 2.60GHZ 12 5,711 68,532 Intel
36 CORE I7-8550U CPU @ 1.80GHZ 8 7,241 57,928 Intel
37 CORE I7-3770 CPU @ 3.40GHZ 8 6,309 50,472 Intel