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PROJECT #16946 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 20 March 2023 06:14:56

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 20 March 2023 06:14:56

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 23,468 750,976 AMD
2 RYZEN 9 5950X 16-CORE 32 16,344 523,008 AMD
3 RYZEN 7 5800X 8-CORE 16 27,553 440,848 AMD
4 CORE I9-9980XE CPU @ 3.00GHZ 36 11,401 410,436 Intel
5 RYZEN THREADRIPPER 2970WX 24-CORE 48 8,310 398,880 AMD
6 RYZEN 9 5900X 12-CORE 24 16,569 397,656 AMD
7 RYZEN 9 3900XT 12-CORE 24 16,194 388,656 AMD
8 CORE I9-7940X CPU @ 3.10GHZ 28 13,289 372,092 Intel
9 XEON PLATINUM 8124M CPU @ 3.00GHZ 36 9,944 357,984 Intel
10 RYZEN 9 3900 12-CORE 24 14,625 351,000 AMD
11 11TH GEN CORE I7-11700K @ 3.60GHZ 16 20,398 326,368 Intel
12 RYZEN 9 3900X 12-CORE 24 13,532 324,768 AMD
13 EPYC 7302P 16-CORE 32 9,944 318,208 AMD
14 CORE I9-10900X CPU @ 3.70GHZ 20 14,467 289,340 Intel
15 11TH GEN CORE I9-11900K @ 3.50GHZ 16 17,823 285,168 Intel
16 XEON W-2175 CPU @ 2.50GHZ 28 10,068 281,904 Intel
17 CORE I9-7920X CPU @ 2.90GHZ 24 11,697 280,728 Intel
18 XEON CPU E5-2667 V2 @ 3.30GHZ 32 8,680 277,760 Intel
19 CORE I7-8700 CPU @ 3.20GHZ 12 21,288 255,456 Intel
20 RYZEN THREADRIPPER 3960X 24-CORE 48 4,655 223,440 AMD
21 RYZEN 5 5600X 6-CORE 12 18,577 222,924 AMD
22 RYZEN 7 4800H 16 13,779 220,464 AMD
23 RYZEN 7 3800X 8-CORE 16 13,303 212,848 AMD
24 RYZEN 7 3700X 8-CORE 16 13,228 211,648 AMD
25 CORE I7-10700K CPU @ 3.80GHZ 16 13,053 208,848 Intel
26 RYZEN 5 3600X 6-CORE 12 17,343 208,116 AMD
27 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,927 190,248 Intel
28 RYZEN 5 1600X SIX-CORE 12 15,570 186,840 AMD
29 CORE I7-9700K CPU @ 3.60GHZ 8 22,659 181,272 Intel
30 RYZEN 5 3600 6-CORE 12 15,053 180,636 AMD
31 RYZEN 7 2700X EIGHT-CORE 16 9,645 154,320 AMD
32 CORE I5-10400 CPU @ 2.90GHZ 12 11,609 139,308 Intel
33 CORE I7-10870H CPU @ 2.20GHZ 16 8,649 138,384 Intel
34 CORE I7-8700B CPU @ 3.20GHZ 12 11,284 135,408 Intel
35 CORE I5-10400F CPU @ 2.90GHZ 12 11,077 132,924 Intel
36 EPYC 7571 32-CORE 64 1,901 121,664 AMD
37 CORE I5-9400F CPU @ 2.90GHZ 6 20,046 120,276 Intel
38 CORE I7-6700K CPU @ 4.00GHZ 8 14,957 119,656 Intel
39 RYZEN 5 1600 SIX-CORE 12 9,911 118,932 AMD
40 CORE I7-5930K CPU @ 3.50GHZ 12 8,296 99,552 Intel
41 RYZEN 5 2600 SIX-CORE 12 8,148 97,776 AMD
42 CORE I5-8400 CPU @ 2.80GHZ 6 14,509 87,054 Intel
43 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 10,210 81,680 Intel
44 XEON W-10855M CPU @ 2.80GHZ 12 6,614 79,368 Intel
45 CORE I5-9300H CPU @ 2.40GHZ 8 9,525 76,200 Intel
46 CORE I7-6820HQ CPU @ 2.70GHZ 8 9,384 75,072 Intel
47 CORE I7-6700 CPU @ 3.40GHZ 8 8,540 68,320 Intel
48 RYZEN 5 2600X SIX-CORE 12 5,559 66,708 AMD
49 CORE I7-8550U CPU @ 1.80GHZ 8 6,899 55,192 Intel
50 CORE I7-3770 CPU @ 3.40GHZ 8 6,129 49,032 Intel
51 RYZEN 5 1400 QUAD-CORE 8 5,455 43,640 AMD
52 XEON SILVER 4116 CPU @ 2.10GHZ 24 1,362 32,688 Intel
53 XEON SILVER 4116 CPU %40 2.10GHZ 24 1,223 29,352 Intel
54 CORE I7-3610QM CPU @ 2.30GHZ 8 2,762 22,096 Intel
55 CORE I7-2600 CPU @ 3.40GHZ 8 2,341 18,728 Intel