PROJECT #16986 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 28,468 910,976 AMD
2 RYZEN 7 5800X 8-CORE 16 44,893 718,288 AMD
3 12TH GEN CORE I7-12700K 20 26,739 534,780 Intel
4 RYZEN 9 5950X 16-CORE 32 13,056 417,792 AMD
5 RYZEN 7 3800X 8-CORE 16 20,187 322,992 AMD
6 CORE I9-10850K CPU @ 3.60GHZ 20 14,958 299,160 Intel
7 CORE I9-10900X CPU @ 3.70GHZ 20 14,426 288,520 Intel
8 RYZEN 5 5600X 6-CORE 12 21,126 253,512 AMD
9 CORE I7-8700 CPU @ 3.20GHZ 12 19,905 238,860 Intel
10 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,729 233,496 Intel
11 RYZEN 7 5700G 16 14,512 232,192 AMD
12 RYZEN THREADRIPPER 3960X 24-CORE 48 4,592 220,416 AMD
13 CORE I9-9900K CPU @ 3.60GHZ 16 13,337 213,392 Intel
14 CORE I7-8700K CPU @ 3.70GHZ 12 16,039 192,468 Intel
15 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,727 188,356 Intel
16 CORE I5-10400 CPU @ 2.90GHZ 12 14,171 170,052 Intel
17 CORE I7-10700 CPU @ 2.90GHZ 16 10,606 169,696 Intel
18 RYZEN 7 2700X EIGHT-CORE 16 10,123 161,968 AMD
19 RYZEN 5 3600 6-CORE 12 11,480 137,760 AMD
20 XEON CPU E5-2698 V4 @ 2.20GHZ 16 8,009 128,144 Intel
21 RYZEN 7 PRO 4750G 16 7,368 117,888 AMD
22 CORE I7-9750H CPU @ 2.60GHZ 12 9,053 108,636 Intel
23 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,909 106,908 Intel
24 CORE I7-6700K CPU @ 4.00GHZ 8 11,486 91,888 Intel
25 EPYC 7251 8-CORE 16 4,683 74,928 AMD
26 RYZEN 7 3700X 8-CORE 16 4,322 69,152 AMD
27 CORE I5-10500T CPU @ 2.30GHZ 12 5,569 66,828 Intel
28 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,850 62,800 Intel
29 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,554 54,648 Intel
30 XEON CPU E3-1240 V2 @ 3.40GHZ 8 6,463 51,704 Intel
31 11TH GEN CORE I5-1145G7 @ 2.60GHZ 8 5,776 46,208 Intel
32 CORE I5-8259U CPU @ 2.30GHZ 8 5,761 46,088 Intel