PROJECT #16986 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 01 December 2022 06:13:29

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 01 December 2022 06:13:29

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 26,326 842,432 AMD
2 RYZEN 7 5800X 8-CORE 16 40,069 641,104 AMD
3 12TH GEN CORE I7-12700K 20 27,281 545,620 Intel
4 RYZEN 9 5950X 16-CORE 32 16,909 541,088 AMD
5 12TH GEN CORE I9-12900K 24 20,042 481,008 Intel
6 RYZEN 9 3900 12-CORE 24 19,524 468,576 AMD
7 RYZEN 7 5700G 16 28,057 448,912 AMD
8 RYZEN 7 5700X 8-CORE 16 25,401 406,416 AMD
9 RYZEN 7 3800X 8-CORE 16 20,187 322,992 AMD
10 CORE I9-10900X CPU @ 3.70GHZ 20 15,072 301,440 Intel
11 CORE I9-10850K CPU @ 3.60GHZ 20 14,187 283,740 Intel
12 RYZEN 9 5900 12-CORE 24 10,572 253,728 AMD
13 RYZEN 5 5600G 12 19,933 239,196 AMD
14 CORE I7-8700 CPU @ 3.20GHZ 12 19,464 233,568 Intel
15 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,729 233,496 Intel
16 RYZEN 9 3900X 12-CORE 24 9,501 228,024 AMD
17 RYZEN 5 5600X 6-CORE 12 18,516 222,192 AMD
18 RYZEN THREADRIPPER 3960X 24-CORE 48 4,592 220,416 AMD
19 CORE I7-9700K CPU @ 3.60GHZ 8 26,145 209,160 Intel
20 CORE I7-8700K CPU @ 3.70GHZ 12 16,039 192,468 Intel
21 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,727 188,356 Intel
22 RYZEN 5 3600 6-CORE 12 14,544 174,528 AMD
23 CORE I9-9900K CPU @ 3.60GHZ 16 10,762 172,192 Intel
24 CORE I5-10400 CPU @ 2.90GHZ 12 14,171 170,052 Intel
25 CORE I7-10700 CPU @ 2.90GHZ 16 10,606 169,696 Intel
26 RYZEN 7 2700X EIGHT-CORE 16 10,032 160,512 AMD
27 APPLE M1 MAX 10 15,804 158,040 Apple
28 RYZEN 7 PRO 4750G 16 8,719 139,504 AMD
29 XEON CPU E5-2698 V4 @ 2.20GHZ 16 8,009 128,144 Intel
30 CORE I7-9750H CPU @ 2.60GHZ 12 9,053 108,636 Intel
31 RYZEN 7 5800HS 16 6,248 99,968 AMD
32 CORE I7-10700T CPU @ 2.00GHZ 16 6,012 96,192 Intel
33 CORE I7-6700K CPU @ 4.00GHZ 8 11,486 91,888 Intel
34 11TH GEN CORE I5-11400 @ 2.60GHZ 12 6,775 81,300 Intel
35 RYZEN 7 3700X 8-CORE 16 5,076 81,216 AMD
36 EPYC 7251 8-CORE 16 4,683 74,928 AMD
37 XEON CPU X5660 @ 2.80GHZ 24 2,956 70,944 Intel
38 CORE I9-8950HK CPU @ 2.90GHZ 12 5,692 68,304 Intel
39 CORE I5-10500T CPU @ 2.30GHZ 12 5,569 66,828 Intel
40 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,853 62,824 Intel
41 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,554 54,648 Intel
42 XEON CPU E3-1240 V2 @ 3.40GHZ 8 6,463 51,704 Intel
43 11TH GEN CORE I5-1145G7 @ 2.60GHZ 8 5,776 46,208 Intel
44 CORE I5-8259U CPU @ 2.30GHZ 8 5,761 46,088 Intel
45 XEON CPU E5-2697 V2 @ 2.70GHZ 24 1,483 35,592 Intel
46 CORE I7-2760QM CPU @ 2.40GHZ 8 2,861 22,888 Intel
47 RYZEN 7 3700U 8 2,471 19,768 AMD