PROJECT #16986 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 28,468 910,976 AMD
2 RYZEN 7 5800X 8-CORE 16 44,893 718,288 AMD
3 RYZEN 9 5950X 16-CORE 32 13,099 419,168 AMD
4 RYZEN 7 3800X 8-CORE 16 20,187 322,992 AMD
5 CORE I9-10850K CPU @ 3.60GHZ 20 14,958 299,160 Intel
6 CORE I9-10900X CPU @ 3.70GHZ 20 14,426 288,520 Intel
7 RYZEN 5 5600X 6-CORE 12 22,509 270,108 AMD
8 CORE I7-8700 CPU @ 3.20GHZ 12 19,905 238,860 Intel
9 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,729 233,496 Intel
10 RYZEN THREADRIPPER 3960X 24-CORE 48 4,592 220,416 AMD
11 CORE I9-9900K CPU @ 3.60GHZ 16 13,337 213,392 Intel
12 CORE I7-8700K CPU @ 3.70GHZ 12 16,039 192,468 Intel
13 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,727 188,356 Intel
14 CORE I5-10400 CPU @ 2.90GHZ 12 14,171 170,052 Intel
15 CORE I7-10700 CPU @ 2.90GHZ 16 10,606 169,696 Intel
16 RYZEN 7 2700X EIGHT-CORE 16 10,123 161,968 AMD
17 RYZEN 5 3600 6-CORE 12 11,480 137,760 AMD
18 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,909 106,908 Intel
19 CORE I7-6700K CPU @ 4.00GHZ 8 11,486 91,888 Intel
20 EPYC 7251 8-CORE 16 4,683 74,928 AMD
21 CORE I7-4770HQ CPU @ 2.20GHZ 8 8,444 67,552 Intel
22 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,554 54,648 Intel
23 CORE I5-8259U CPU @ 2.30GHZ 8 5,761 46,088 Intel