PROJECT #16986 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank Project	CPU Model	Logical Processors (LP)	PPD-PLP AVG PPD per 1 LP	ALL LP-PPD (Estimated)	Make
1	RYZEN 9 3950X 16-CORE	32	26,326	842,432	AMD
2	RYZEN 7 5800X 8-CORE	16	40,069	641,104	AMD
3	RYZEN 7 7700X 8-CORE	16	38,407	614,512	AMD
4	12TH GEN CORE I7-12700K	20	27,281	545,620	Intel
5	RYZEN 9 5950X 16-CORE	32	15,916	509,312	AMD
6	12TH GEN CORE I9-12900K	24	20,042	481,008	Intel
7	RYZEN 5 5600 6-CORE	12	39,076	468,912	AMD
8	RYZEN 9 3900 12-CORE	24	19,524	468,576	AMD
9	RYZEN 7 5700X 8-CORE	16	24,759	396,144	AMD
10	RYZEN 7 5700G	16	23,715	379,440	AMD
11	RYZEN 7 3800X 8-CORE	16	20,575	329,200	AMD
12	RYZEN 9 5900X 12-CORE	24	12,864	308,736	AMD
13	CORE I9-10900X CPU @ 3.70GHZ	20	15,072	301,440	Intel
14	CORE I9-10850K CPU @ 3.60GHZ	20	14,187	283,740	Intel
15	12TH GEN CORE I5-12600K	16	17,619	281,904	Intel
16	RYZEN 9 5900 12-CORE	24	10,572	253,728	AMD
17	RYZEN 5 5600G	12	19,933	239,196	AMD
18	CORE I7-8700 CPU @ 3.20GHZ	12	19,464	233,568	Intel
19	XEON CPU E5-2680 V3 @ 2.50GHZ	24	9,729	233,496	Intel
20	RYZEN 9 3900X 12-CORE	24	9,501	228,024	AMD
21	RYZEN 5 5600X 6-CORE	12	18,516	222,192	AMD
22	RYZEN THREADRIPPER 3960X 24-CORE	48	4,592	220,416	AMD
23	CORE I7-9700K CPU @ 3.60GHZ	8	27,429	219,432	Intel
24	CORE I7-8700K CPU @ 3.70GHZ	12	16,039	192,468	Intel
25	RYZEN 5 3500 6-CORE	6	31,659	189,954	AMD
26	XEON CPU E5-2690 V4 @ 2.60GHZ	28	6,727	188,356	Intel
27	RYZEN 5 3600 6-CORE	12	14,544	174,528	AMD
28	CORE I9-9900K CPU @ 3.60GHZ	16	10,762	172,192	Intel
29	CORE I5-10400 CPU @ 2.90GHZ	12	14,171	170,052	Intel
30	CORE I7-10700 CPU @ 2.90GHZ	16	10,606	169,696	Intel
31	RYZEN 7 2700X EIGHT-CORE	16	10,032	160,512	AMD
32	APPLE M1 MAX	10	15,804	158,040	Apple
33	RYZEN 7 PRO 4750G	16	9,164	146,624	AMD
34	XEON CPU E5-2698 V4 @ 2.20GHZ	16	8,009	128,144	Intel
35	CORE I7-9750H CPU @ 2.60GHZ	12	9,040	108,480	Intel
36	RYZEN 7 5800HS	16	6,248	99,968	AMD
37	CORE I7-6700K CPU @ 4.00GHZ	8	11,486	91,888	Intel
38	CORE I7-10700T CPU @ 2.00GHZ	16	5,647	90,352	Intel
39	CORE I7-8705G CPU @ 3.10GHZ	8	11,161	89,288	Intel
40	RYZEN THREADRIPPER 2950X 16-CORE	32	2,693	86,176	AMD
41	11TH GEN CORE I5-11400 @ 2.60GHZ	12	6,775	81,300	Intel
42	RYZEN 7 3700X 8-CORE	16	5,076	81,216	AMD
43	CORE I9-8950HK CPU @ 2.90GHZ	12	6,605	79,260	Intel
44	EPYC 7251 8-CORE	16	4,683	74,928	AMD
45	XEON CPU X5660 @ 2.80GHZ	24	2,956	70,944	Intel
46	CORE I5-10500T CPU @ 2.30GHZ	12	5,569	66,828	Intel
47	CORE I7-4770HQ CPU @ 2.20GHZ	8	7,853	62,824	Intel
48	XEON CPU E5-2620 0 @ 2.00GHZ	12	4,554	54,648	Intel
49	XEON CPU L5640 @ 2.27GHZ	24	2,187	52,488	Intel
50	CORE I7-5820K CPU @ 3.30GHZ	12	4,368	52,416	Intel
51	XEON CPU E3-1240 V2 @ 3.40GHZ	8	6,463	51,704	Intel
52	APPLE M1 PRO	10	4,699	46,990	Apple
53	11TH GEN CORE I5-1145G7 @ 2.60GHZ	8	5,776	46,208	Intel
54	CORE I5-8259U CPU @ 2.30GHZ	8	5,761	46,088	Intel
55	XEON CPU E5-2697 V2 @ 2.70GHZ	24	1,385	33,240	Intel
56	CORE I7-2760QM CPU @ 2.40GHZ	8	2,861	22,888	Intel
57	RYZEN 7 3700U	8	2,471	19,768	AMD