PROJECT #16987 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 26 June 2022 09:57:06

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 26 June 2022 09:57:06

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 40,205 643,280 AMD
2 12TH GEN CORE I7-12700K 20 21,738 434,760 Intel
3 RYZEN 9 3950X 16-CORE 32 11,394 364,608 AMD
4 RYZEN 9 3900XT 12-CORE 24 14,289 342,936 AMD
5 RYZEN 7 3800X 8-CORE 16 20,798 332,768 AMD
6 CORE I9-10850K CPU @ 3.60GHZ 20 15,839 316,780 Intel
7 CORE I9-10900X CPU @ 3.70GHZ 20 14,184 283,680 Intel
8 RYZEN 9 3900X 12-CORE 24 11,101 266,424 AMD
9 RYZEN 7 3700X 8-CORE 16 15,432 246,912 AMD
10 CORE I9-9900K CPU @ 3.60GHZ 16 15,300 244,800 Intel
11 CORE I7-8700 CPU @ 3.20GHZ 12 19,020 228,240 Intel
12 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,865 192,220 Intel
13 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,463 179,112 Intel
14 CORE I7-9700 CPU @ 3.00GHZ 8 21,508 172,064 Intel
15 CORE I5-10400 CPU @ 2.90GHZ 12 11,634 139,608 Intel
16 RYZEN 5 3600 6-CORE 12 11,126 133,512 AMD
17 RYZEN 5 1600 SIX-CORE 12 9,657 115,884 AMD
18 CORE I7-8705G CPU @ 3.10GHZ 8 10,480 83,840 Intel
19 RYZEN 5 2600 SIX-CORE 12 6,922 83,064 AMD
20 CORE I9-8950HK CPU @ 2.90GHZ 12 6,295 75,540 Intel
21 XEON W-10855M CPU @ 2.80GHZ 12 4,986 59,832 Intel
22 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 6,747 53,976 Intel