PROJECT #16982 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 27 September 2021 17:59:05

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 27 September 2021 17:59:05

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 38,670 618,720 AMD
2 RYZEN 9 3950X 16-CORE 32 17,264 552,448 AMD
3 RYZEN 7 3800X 8-CORE 16 24,639 394,224 AMD
4 XEON CPU E5-2680 V3 @ 2.50GHZ 24 12,977 311,448 Intel
5 CORE I9-10900X CPU @ 3.70GHZ 20 14,763 295,260 Intel
6 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,515 282,180 Intel
7 CORE I9-10850K CPU @ 3.60GHZ 20 13,396 267,920 Intel
8 RYZEN 5 5600X 6-CORE 12 20,963 251,556 AMD
9 CORE I7-8700 CPU @ 3.20GHZ 12 20,050 240,600 Intel
10 11TH GEN CORE I7-11700K @ 3.60GHZ 16 14,600 233,600 Intel
11 RYZEN THREADRIPPER 3960X 24-CORE 48 4,463 214,224 AMD
12 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,777 189,756 Intel
13 RYZEN 7 2700X EIGHT-CORE 16 10,892 174,272 AMD
14 CORE I5-10400F CPU @ 2.90GHZ 12 14,223 170,676 Intel
15 CORE I7-5820K CPU @ 3.30GHZ 12 10,980 131,760 Intel
16 RYZEN 5 3600 6-CORE 12 10,937 131,244 AMD
17 11TH GEN CORE I5-11400 @ 2.60GHZ 12 7,533 90,396 Intel
18 CORE I7-10750H CPU @ 2.60GHZ 12 4,646 55,752 Intel
19 CORE I7-8565U CPU @ 1.80GHZ 8 4,635 37,080 Intel