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PROJECT #16982 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Saturday, 01 April 2023 12:14:50

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Saturday, 01 April 2023 12:14:50

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 7 5800X 8-CORE 16 45,143 722,288 AMD
2 RYZEN 9 5950X 16-CORE 32 21,825 698,400 AMD
3 RYZEN 7 7700X 8-CORE 16 42,094 673,504 AMD
4 RYZEN 9 7900X 12-CORE 24 27,646 663,504 AMD
5 12TH GEN CORE I7-12700K 20 30,414 608,280 Intel
6 RYZEN 9 3950X 16-CORE 32 17,264 552,448 AMD
7 12TH GEN CORE I9-12900K 24 21,602 518,448 Intel
8 RYZEN 9 3900 12-CORE 24 20,105 482,520 AMD
9 RYZEN 9 5900X 12-CORE 24 19,748 473,952 AMD
10 RYZEN 7 5800X3D 8-CORE 16 27,705 443,280 AMD
11 RYZEN 7 5700X 8-CORE 16 26,604 425,664 AMD
12 RYZEN 5 5600G 12 32,197 386,364 AMD
13 RYZEN 7 3800X 8-CORE 16 21,532 344,512 AMD
14 XEON CPU E5-2680 V3 @ 2.50GHZ 24 12,977 311,448 Intel
15 CORE I9-10900X CPU @ 3.70GHZ 20 14,763 295,260 Intel
16 RYZEN 9 3900X 12-CORE 24 12,206 292,944 AMD
17 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,515 282,180 Intel
18 CORE I9-10850K CPU @ 3.60GHZ 20 13,447 268,940 Intel
19 RYZEN 7 5800H 16 15,153 242,448 AMD
20 11TH GEN CORE I7-11700K @ 3.60GHZ 16 14,600 233,600 Intel
21 CORE I7-8700 CPU @ 3.20GHZ 12 19,401 232,812 Intel
22 RYZEN 5 5600X 6-CORE 12 18,864 226,368 AMD
23 APPLE M1 MAX 10 21,692 216,920 Apple
24 RYZEN THREADRIPPER 3960X 24-CORE 48 4,463 214,224 AMD
25 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,777 189,756 Intel
26 CORE I7-9700K CPU @ 3.60GHZ 8 23,542 188,336 Intel
27 RYZEN 7 5700G 16 11,492 183,872 AMD
28 RYZEN 7 2700X EIGHT-CORE 16 10,892 174,272 AMD
29 CORE I5-10400F CPU @ 2.90GHZ 12 14,223 170,676 Intel
30 RYZEN 5 3600 6-CORE 12 13,855 166,260 AMD
31 RYZEN 7 PRO 4750G 16 10,061 160,976 AMD
32 13TH GEN CORE I9-13900K 32 5,023 160,736 Intel
33 RYZEN 5 3500 6-CORE 6 26,655 159,930 AMD
34 RYZEN 7 3700X 8-CORE 16 9,780 156,480 AMD
35 12TH GEN CORE I9-12900H 20 7,754 155,080 Intel
36 CORE I7-9700 CPU @ 3.00GHZ 8 16,889 135,112 Intel
37 XEON CPU E5-2698 V4 @ 2.20GHZ 16 8,363 133,808 Intel
38 CORE I7-5820K CPU @ 3.30GHZ 12 10,808 129,696 Intel
39 CORE I7-7700K CPU @ 4.20GHZ 8 15,609 124,872 Intel
40 12TH GEN CORE I3-12100F 8 14,239 113,912 Intel
41 CORE I7-9750H CPU @ 2.60GHZ 12 9,414 112,968 Intel
42 CORE I5-9500 CPU @ 3.00GHZ 6 18,481 110,886 Intel
43 CORE I5-10400 CPU @ 2.90GHZ 12 8,549 102,588 Intel
44 CORE I7-10700T CPU @ 2.00GHZ 16 6,353 101,648 Intel
45 11TH GEN CORE I5-11400 @ 2.60GHZ 12 7,928 95,136 Intel
46 CORE I7-8705G CPU @ 3.10GHZ 8 11,323 90,584 Intel
47 CORE I9-8950HK CPU @ 2.90GHZ 12 6,960 83,520 Intel
48 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,323 82,584 Intel
49 XEON CPU E5-2697 V2 @ 2.70GHZ 24 3,295 79,080 Intel
50 APPLE M1 8 9,125 73,000 Apple
51 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,433 70,928 Intel
52 XEON CPU E5-1630 V3 @ 3.70GHZ 8 8,854 70,832 Intel
53 CORE I5-8250U CPU @ 1.60GHZ 8 8,398 67,184 Intel
54 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,765 62,120 Intel
55 CORE I7-6700K CPU @ 4.00GHZ 8 7,248 57,984 Intel
56 CORE I7-3770 CPU @ 3.40GHZ 8 7,064 56,512 Intel
57 CORE I7-10750H CPU @ 2.60GHZ 12 4,646 55,752 Intel
58 12TH GEN CORE I7-12700KF 20 2,559 51,180 Intel
59 RYZEN 5 2400G 8 6,339 50,712 AMD
60 CORE I7-4770K CPU @ 3.50GHZ 8 6,262 50,096 Intel
61 APPLE M1 PRO 10 4,882 48,820 Apple
62 XEON CPU E5-2650L V4 @ 1.70GHZ 28 1,442 40,376 Intel
63 RYZEN 5 5500U 12 3,221 38,652 AMD
64 CORE I7-7700HQ CPU @ 2.80GHZ 8 4,786 38,288 Intel
65 CORE I7-8565U CPU @ 1.80GHZ 8 4,635 37,080 Intel
66 CORE I7-3770K CPU @ 3.50GHZ 8 3,075 24,600 Intel
67 CORE I7-2760QM CPU @ 2.40GHZ 8 2,651 21,208 Intel
68 CORE I5-8350U CPU @ 1.70GHZ 8 2,025 16,200 Intel
69 CORE I5-10310U CPU @ 1.70GHZ 8 1,917 15,336 Intel