PROJECT #16982 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 07 December 2022 06:13:28

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 07 December 2022 06:13:28

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 45,143 722,288 AMD
2 RYZEN 9 5950X 16-CORE 32 22,518 720,576 AMD
3 RYZEN 7 7700X 8-CORE 16 42,289 676,624 AMD
4 12TH GEN CORE I7-12700K 20 30,414 608,280 Intel
5 RYZEN 7 5800X3D 8-CORE 16 36,610 585,760 AMD
6 RYZEN 9 3950X 16-CORE 32 17,264 552,448 AMD
7 12TH GEN CORE I9-12900K 24 21,602 518,448 Intel
8 RYZEN 9 3900 12-CORE 24 20,105 482,520 AMD
9 RYZEN 9 5900X 12-CORE 24 20,058 481,392 AMD
10 RYZEN 7 5700X 8-CORE 16 26,361 421,776 AMD
11 RYZEN 5 5600G 12 32,197 386,364 AMD
12 RYZEN 7 3800X 8-CORE 16 21,867 349,872 AMD
13 RYZEN 9 3900X 12-CORE 24 13,333 319,992 AMD
14 XEON CPU E5-2680 V3 @ 2.50GHZ 24 12,977 311,448 Intel
15 CORE I9-10900X CPU @ 3.70GHZ 20 14,763 295,260 Intel
16 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,515 282,180 Intel
17 CORE I9-10850K CPU @ 3.60GHZ 20 13,447 268,940 Intel
18 RYZEN 7 5800H 16 15,153 242,448 AMD
19 CORE I7-8700 CPU @ 3.20GHZ 12 19,498 233,976 Intel
20 11TH GEN CORE I7-11700K @ 3.60GHZ 16 14,600 233,600 Intel
21 RYZEN 5 5600X 6-CORE 12 18,260 219,120 AMD
22 APPLE M1 MAX 10 21,692 216,920 Apple
23 RYZEN THREADRIPPER 3960X 24-CORE 48 4,463 214,224 AMD
24 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,777 189,756 Intel
25 CORE I7-9700K CPU @ 3.60GHZ 8 22,418 179,344 Intel
26 RYZEN 7 2700X EIGHT-CORE 16 10,892 174,272 AMD
27 CORE I5-10400F CPU @ 2.90GHZ 12 14,223 170,676 Intel
28 12TH GEN CORE I3-12100F 8 21,062 168,496 Intel
29 RYZEN 5 3600 6-CORE 12 13,875 166,500 AMD
30 RYZEN 7 PRO 4750G 16 10,081 161,296 AMD
31 12TH GEN CORE I9-12900H 20 7,754 155,080 Intel
32 RYZEN 7 3700X 8-CORE 16 9,128 146,048 AMD
33 CORE I7-9700 CPU @ 3.00GHZ 8 16,889 135,112 Intel
34 XEON CPU E5-2698 V4 @ 2.20GHZ 16 8,363 133,808 Intel
35 CORE I7-7700K CPU @ 4.20GHZ 8 16,460 131,680 Intel
36 CORE I7-5820K CPU @ 3.30GHZ 12 10,808 129,696 Intel
37 CORE I7-9750H CPU @ 2.60GHZ 12 9,414 112,968 Intel
38 CORE I5-9500 CPU @ 3.00GHZ 6 18,481 110,886 Intel
39 CORE I5-10400 CPU @ 2.90GHZ 12 8,549 102,588 Intel
40 CORE I7-10700T CPU @ 2.00GHZ 16 6,353 101,648 Intel
41 11TH GEN CORE I5-11400 @ 2.60GHZ 12 7,928 95,136 Intel
42 CORE I7-8705G CPU @ 3.10GHZ 8 11,323 90,584 Intel
43 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,323 82,584 Intel
44 CORE I9-8950HK CPU @ 2.90GHZ 12 6,776 81,312 Intel
45 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,433 70,928 Intel
46 XEON CPU E5-1630 V3 @ 3.70GHZ 8 8,854 70,832 Intel
47 CORE I5-8250U CPU @ 1.60GHZ 8 8,398 67,184 Intel
48 CORE I7-6700K CPU @ 4.00GHZ 8 8,243 65,944 Intel
49 XEON CPU E5-2697 V2 @ 2.70GHZ 24 2,721 65,304 Intel
50 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,765 62,120 Intel
51 CORE I7-3770 CPU @ 3.40GHZ 8 7,064 56,512 Intel
52 CORE I7-10750H CPU @ 2.60GHZ 12 4,646 55,752 Intel
53 CORE I7-4770K CPU @ 3.50GHZ 8 6,262 50,096 Intel
54 APPLE M1 PRO 10 4,993 49,930 Apple
55 XEON CPU E5-2650L V4 @ 1.70GHZ 28 1,442 40,376 Intel
56 CORE I7-7700HQ CPU @ 2.80GHZ 8 4,663 37,304 Intel
57 CORE I7-8565U CPU @ 1.80GHZ 8 4,635 37,080 Intel
58 CORE I7-3770K CPU @ 3.50GHZ 8 3,075 24,600 Intel
59 CORE I7-2760QM CPU @ 2.40GHZ 8 2,651 21,208 Intel
60 CORE I5-8350U CPU @ 1.70GHZ 8 2,007 16,056 Intel
61 CORE I5-10310U CPU @ 1.70GHZ 8 1,917 15,336 Intel