PROJECT #16989 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 04 December 2022 18:13:26

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 04 December 2022 18:13:26

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X3D 8-CORE 16 50,234 803,744 AMD
2 12TH GEN CORE I5-12600K 16 45,347 725,552 Intel
3 RYZEN 7 5800X 8-CORE 16 37,655 602,480 AMD
4 RYZEN 9 3900 12-CORE 24 22,819 547,656 AMD
5 RYZEN 9 5950X 16-CORE 32 17,029 544,928 AMD
6 12TH GEN CORE I9-12900K 24 20,799 499,176 Intel
7 RYZEN 9 5900X 12-CORE 24 19,811 475,464 AMD
8 RYZEN 7 5700X 8-CORE 16 29,581 473,296 AMD
9 12TH GEN CORE I7-12700K 20 22,277 445,540 Intel
10 11TH GEN CORE I7-11700K @ 3.60GHZ 16 24,941 399,056 Intel
11 RYZEN 9 3950X 16-CORE 32 12,347 395,104 AMD
12 RYZEN 9 3900XT 12-CORE 24 14,481 347,544 AMD
13 RYZEN 7 3800X 8-CORE 16 20,817 333,072 AMD
14 CORE I9-10850K CPU @ 3.60GHZ 20 16,442 328,840 Intel
15 RYZEN THREADRIPPER 1950X 16-CORE 32 10,034 321,088 AMD
16 CORE I9-10900X CPU @ 3.70GHZ 20 13,691 273,820 Intel
17 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,846 260,304 Intel
18 RYZEN 5 5600X 6-CORE 12 21,259 255,108 AMD
19 CORE I9-9900K CPU @ 3.60GHZ 16 15,509 248,144 Intel
20 CORE I7-8700 CPU @ 3.20GHZ 12 19,422 233,064 Intel
21 RYZEN 7 3700X 8-CORE 16 14,527 232,432 AMD
22 12TH GEN CORE I7-12700 20 11,536 230,720 Intel
23 RYZEN 9 5900HS 16 14,017 224,272 AMD
24 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,872 192,416 Intel
25 RYZEN 5 3600 6-CORE 12 15,332 183,984 AMD
26 RYZEN 5 5600G 12 15,218 182,616 AMD
27 CORE I7-9700 CPU @ 3.00GHZ 8 21,261 170,088 Intel
28 XEON CPU E5-2660 V3 @ 2.60GHZ 20 8,293 165,860 Intel
29 RYZEN 7 PRO 4750G 16 10,279 164,464 AMD
30 CORE I5-10400 CPU @ 2.90GHZ 12 13,207 158,484 Intel
31 11TH GEN CORE I5-11400 @ 2.60GHZ 12 10,470 125,640 Intel
32 CORE I7-10700T CPU @ 2.00GHZ 16 7,316 117,056 Intel
33 APPLE M1 MAX 10 10,960 109,600 Apple
34 RYZEN 5 2600X SIX-CORE 12 8,857 106,284 AMD
35 CORE I7-8705G CPU @ 3.10GHZ 8 11,603 92,824 Intel
36 CORE I7-4790K CPU @ 4.00GHZ 8 10,948 87,584 Intel
37 RYZEN 5 1600 SIX-CORE 12 7,122 85,464 AMD
38 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,575 84,600 Intel
39 CORE I3-10100 CPU @ 3.60GHZ 8 9,919 79,352 Intel
40 CORE I7-6700K CPU @ 4.00GHZ 8 9,676 77,408 Intel
41 CORE I9-8950HK CPU @ 2.90GHZ 12 6,349 76,188 Intel
42 EPYC 7251 8-CORE 16 4,685 74,960 AMD
43 APPLE M1 8 8,406 67,248 Apple
44 XEON W-10855M CPU @ 2.80GHZ 12 5,452 65,424 Intel
45 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,587 60,696 Intel
46 CORE I7-4790T CPU @ 2.70GHZ 8 7,431 59,448 Intel
47 CORE I7-4770K CPU @ 3.50GHZ 8 6,629 53,032 Intel
48 CORE I7-3770 CPU @ 3.40GHZ 8 6,384 51,072 Intel
49 XEON CPU E31245 @ 3.30GHZ 8 4,827 38,616 Intel
50 CORE I7 CPU 975 @ 3.33GHZ 8 3,782 30,256 Intel