PROJECT #16989 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 20 March 2023 06:14:56

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 20 March 2023 06:14:56

Rank Project	CPU Model	Logical Processors (LP)	PPD-PLP AVG PPD per 1 LP	ALL LP-PPD (Estimated)	Make
1	13TH GEN CORE I9-13900KS	32	27,524	880,768	Intel
2	RYZEN 7 5800X3D 8-CORE	16	50,234	803,744	AMD
3	12TH GEN CORE I5-12600K	16	45,347	725,552	Intel
4	RYZEN 7 7700X 8-CORE	16	37,770	604,320	AMD
5	RYZEN 7 5800X 8-CORE	16	37,655	602,480	AMD
6	RYZEN 9 3900 12-CORE	24	22,819	547,656	AMD
7	RYZEN 9 5950X 16-CORE	32	17,029	544,928	AMD
8	12TH GEN CORE I9-12900K	24	20,799	499,176	Intel
9	RYZEN 9 5900X 12-CORE	24	19,855	476,520	AMD
10	RYZEN 7 5700X 8-CORE	16	29,046	464,736	AMD
11	12TH GEN CORE I7-12700K	20	22,277	445,540	Intel
12	11TH GEN CORE I7-11700K @ 3.60GHZ	16	24,941	399,056	Intel
13	RYZEN 9 3950X 16-CORE	32	12,347	395,104	AMD
14	RYZEN 9 3900XT 12-CORE	24	14,481	347,544	AMD
15	RYZEN 7 3800X 8-CORE	16	20,817	333,072	AMD
16	CORE I9-10850K CPU @ 3.60GHZ	20	16,442	328,840	Intel
17	RYZEN THREADRIPPER 1950X 16-CORE	32	10,034	321,088	AMD
18	CORE I9-10900X CPU @ 3.70GHZ	20	13,691	273,820	Intel
19	XEON CPU E5-2680 V3 @ 2.50GHZ	24	10,846	260,304	Intel
20	RYZEN 5 5600X 6-CORE	12	21,259	255,108	AMD
21	CORE I9-9900K CPU @ 3.60GHZ	16	15,509	248,144	Intel
22	CORE I7-8700 CPU @ 3.20GHZ	12	19,422	233,064	Intel
23	RYZEN 7 3700X 8-CORE	16	14,527	232,432	AMD
24	12TH GEN CORE I7-12700	20	11,536	230,720	Intel
25	RYZEN 9 3900X 12-CORE	24	9,384	225,216	AMD
26	RYZEN 9 5900HS	16	14,017	224,272	AMD
27	XEON CPU E5-2690 V4 @ 2.60GHZ	28	6,872	192,416	Intel
28	RYZEN 5 3600 6-CORE	12	15,332	183,984	AMD
29	RYZEN 5 5600G	12	15,218	182,616	AMD
30	CORE I7-9700 CPU @ 3.00GHZ	8	21,261	170,088	Intel
31	XEON CPU E5-2660 V3 @ 2.60GHZ	20	8,293	165,860	Intel
32	RYZEN 7 PRO 4750G	16	10,279	164,464	AMD
33	CORE I5-10400 CPU @ 2.90GHZ	12	13,207	158,484	Intel
34	CORE I7-5820K CPU @ 3.30GHZ	12	10,798	129,576	Intel
35	11TH GEN CORE I5-11400 @ 2.60GHZ	12	10,470	125,640	Intel
36	CORE I7-10700T CPU @ 2.00GHZ	16	7,316	117,056	Intel
37	APPLE M1 MAX	10	10,960	109,600	Apple
38	RYZEN 5 2600X SIX-CORE	12	8,857	106,284	AMD
39	CORE I7-8705G CPU @ 3.10GHZ	8	11,603	92,824	Intel
40	CORE I7-4790K CPU @ 4.00GHZ	8	10,948	87,584	Intel
41	RYZEN 5 1600 SIX-CORE	12	7,122	85,464	AMD
42	XEON CPU E3-1270 V5 @ 3.60GHZ	8	10,575	84,600	Intel
43	CORE I3-10100 CPU @ 3.60GHZ	8	9,919	79,352	Intel
44	CORE I7-6700K CPU @ 4.00GHZ	8	9,676	77,408	Intel
45	CORE I9-8950HK CPU @ 2.90GHZ	12	6,349	76,188	Intel
46	EPYC 7251 8-CORE	16	4,685	74,960	AMD
47	CORE I7-4770 CPU @ 3.40GHZ	8	8,610	68,880	Intel
48	APPLE M1	8	8,406	67,248	Apple
49	XEON W-10855M CPU @ 2.80GHZ	12	5,452	65,424	Intel
50	CORE I7-4770HQ CPU @ 2.20GHZ	8	7,642	61,136	Intel
51	CORE I7-4790T CPU @ 2.70GHZ	8	7,431	59,448	Intel
52	CORE I7-4770K CPU @ 3.50GHZ	8	6,629	53,032	Intel
53	CORE I7-3770 CPU @ 3.40GHZ	8	6,384	51,072	Intel
54	XEON CPU E31245 @ 3.30GHZ	8	4,827	38,616	Intel
55	CORE I7 CPU 975 @ 3.33GHZ	8	3,782	30,256	Intel