PROJECT #16989 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 27 June 2022 11:45:24

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 27 June 2022 11:45:24

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 37,655 602,480 AMD
2 RYZEN 9 5950X 16-CORE 32 17,029 544,928 AMD
3 RYZEN 9 5900X 12-CORE 24 21,118 506,832 AMD
4 12TH GEN CORE I9-12900K 24 20,799 499,176 Intel
5 RYZEN 7 5700X 8-CORE 16 30,837 493,392 AMD
6 12TH GEN CORE I7-12700K 20 22,822 456,440 Intel
7 RYZEN 9 3950X 16-CORE 32 12,347 395,104 AMD
8 RYZEN 9 3900XT 12-CORE 24 14,481 347,544 AMD
9 RYZEN 7 3800X 8-CORE 16 20,817 333,072 AMD
10 CORE I9-10850K CPU @ 3.60GHZ 20 16,442 328,840 Intel
11 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,846 260,304 Intel
12 RYZEN 5 5600X 6-CORE 12 21,259 255,108 AMD
13 CORE I9-10900X CPU @ 3.70GHZ 20 12,537 250,740 Intel
14 CORE I9-9900K CPU @ 3.60GHZ 16 15,509 248,144 Intel
15 CORE I7-8700 CPU @ 3.20GHZ 12 19,422 233,064 Intel
16 RYZEN 7 3700X 8-CORE 16 14,527 232,432 AMD
17 12TH GEN CORE I7-12700 20 11,536 230,720 Intel
18 RYZEN 9 5900HS 16 14,017 224,272 AMD
19 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,872 192,416 Intel
20 RYZEN 5 3600 6-CORE 12 14,669 176,028 AMD
21 XEON CPU E5-2660 V3 @ 2.60GHZ 20 8,293 165,860 Intel
22 RYZEN 7 PRO 4750G 16 10,279 164,464 AMD
23 CORE I5-10400 CPU @ 2.90GHZ 12 13,207 158,484 Intel
24 11TH GEN CORE I5-11400 @ 2.60GHZ 12 10,470 125,640 Intel
25 CORE I7-10700T CPU @ 2.00GHZ 16 7,316 117,056 Intel
26 CORE I7-4790K CPU @ 4.00GHZ 8 10,948 87,584 Intel
27 RYZEN 5 1600 SIX-CORE 12 7,122 85,464 AMD
28 CORE I3-10100 CPU @ 3.60GHZ 8 9,919 79,352 Intel
29 CORE I7-6700K CPU @ 4.00GHZ 8 9,676 77,408 Intel
30 EPYC 7251 8-CORE 16 4,685 74,960 AMD
31 CORE I9-8950HK CPU @ 2.90GHZ 12 5,859 70,308 Intel
32 XEON W-10855M CPU @ 2.80GHZ 12 5,452 65,424 Intel
33 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,587 60,696 Intel
34 CORE I7-4790T CPU @ 2.70GHZ 8 7,431 59,448 Intel
35 CORE I7-3770 CPU @ 3.40GHZ 8 6,384 51,072 Intel
36 CORE I7-4770K CPU @ 3.50GHZ 8 5,233 41,864 Intel
37 XEON CPU E31245 @ 3.30GHZ 8 4,827 38,616 Intel
38 CORE I7 CPU 975 @ 3.33GHZ 8 3,782 30,256 Intel