PROJECT #16989 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Saturday, 15 January 2022 23:40:54

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Saturday, 15 January 2022 23:40:54

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 37,655 602,480 AMD
2 RYZEN 9 5950X 16-CORE 32 17,924 573,568 AMD
3 RYZEN 9 3950X 16-CORE 32 12,347 395,104 AMD
4 CORE I9-10850K CPU @ 3.60GHZ 20 16,442 328,840 Intel
5 RYZEN 7 3800X 8-CORE 16 20,507 328,112 AMD
6 RYZEN 5 5600X 6-CORE 12 22,185 266,220 AMD
7 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,846 260,304 Intel
8 CORE I9-10900X CPU @ 3.70GHZ 20 12,537 250,740 Intel
9 CORE I9-9900K CPU @ 3.60GHZ 16 15,509 248,144 Intel
10 CORE I7-8700 CPU @ 3.20GHZ 12 19,422 233,064 Intel
11 RYZEN 7 3700X 8-CORE 16 14,527 232,432 AMD
12 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,872 192,416 Intel
13 RYZEN 5 3600 6-CORE 12 14,779 177,348 AMD
14 XEON CPU E5-2660 V3 @ 2.60GHZ 20 8,293 165,860 Intel
15 CORE I5-10400 CPU @ 2.90GHZ 12 13,207 158,484 Intel
16 11TH GEN CORE I5-11400 @ 2.60GHZ 12 10,470 125,640 Intel
17 RYZEN 5 1600 SIX-CORE 12 7,122 85,464 AMD
18 CORE I3-10100 CPU @ 3.60GHZ 8 9,919 79,352 Intel
19 CORE I7-6700K CPU @ 4.00GHZ 8 9,676 77,408 Intel
20 EPYC 7251 8-CORE 16 4,685 74,960 AMD
21 XEON W-10855M CPU @ 2.80GHZ 12 5,452 65,424 Intel
22 CORE I7-4790T CPU @ 2.70GHZ 8 7,431 59,448 Intel
23 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,287 58,296 Intel
24 CORE I9-8950HK CPU @ 2.90GHZ 12 4,627 55,524 Intel
25 CORE I7-3770 CPU @ 3.40GHZ 8 6,384 51,072 Intel
26 CORE I7-4770K CPU @ 3.50GHZ 8 5,233 41,864 Intel
27 CORE I7 CPU 975 @ 3.33GHZ 8 3,878 31,024 Intel