PROJECT #16992 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 01 December 2022 06:13:29

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 01 December 2022 06:13:29

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,011 1,056,352 AMD
2 RYZEN 7 5800X 8-CORE 16 46,225 739,600 AMD
3 RYZEN 9 5950X 16-CORE 32 22,078 706,496 AMD
4 RYZEN 7 5700G 16 41,706 667,296 AMD
5 RYZEN 7 7700X 8-CORE 16 35,939 575,024 AMD
6 12TH GEN CORE I9-12900K 24 20,898 501,552 Intel
7 EPYC 7V12 64-CORE 64 7,432 475,648 AMD
8 RYZEN 9 5900X 12-CORE 24 18,412 441,888 AMD
9 11TH GEN CORE I9-11900K @ 3.50GHZ 16 26,410 422,560 Intel
10 RYZEN 7 5700X 8-CORE 16 24,134 386,144 AMD
11 RYZEN 9 3900X 12-CORE 24 13,854 332,496 AMD
12 CORE I9-10850K CPU @ 3.60GHZ 20 16,469 329,380 Intel
13 RYZEN 7 3800X 8-CORE 16 20,144 322,304 AMD
14 11TH GEN CORE I7-11700K @ 3.60GHZ 16 18,963 303,408 Intel
15 12TH GEN CORE I7-12700K 20 14,383 287,660 Intel
16 RYZEN 5 3600X 6-CORE 12 23,117 277,404 AMD
17 CORE I9-10900X CPU @ 3.70GHZ 20 13,670 273,400 Intel
18 RYZEN 9 3900XT 12-CORE 24 10,289 246,936 AMD
19 RYZEN 9 5900HS 16 15,186 242,976 AMD
20 CORE I9-9900 CPU @ 3.10GHZ 16 14,850 237,600 Intel
21 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,799 235,176 Intel
22 RYZEN THREADRIPPER 3960X 24-CORE 48 4,534 217,632 AMD
23 RYZEN 5 5600X 6-CORE 12 16,972 203,664 AMD
24 CORE I9-9900K CPU @ 3.60GHZ 16 12,664 202,624 Intel
25 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,109 199,052 Intel
26 CORE I7-8700 CPU @ 3.20GHZ 12 16,462 197,544 Intel
27 CORE I9-7920X CPU @ 2.90GHZ 24 7,558 181,392 Intel
28 RYZEN 7 PRO 4750G 16 11,275 180,400 AMD
29 CORE I7-8700K CPU @ 3.70GHZ 12 14,853 178,236 Intel
30 RYZEN 5 3600 6-CORE 12 14,367 172,404 AMD
31 APPLE M1 MAX 10 16,674 166,740 Apple
32 12TH GEN CORE I5-12400 12 13,276 159,312 Intel
33 RYZEN 7 3700X 8-CORE 16 9,902 158,432 AMD
34 XEON CPU E5-2698 V4 @ 2.20GHZ 16 9,601 153,616 Intel
35 CORE I7-9700K CPU @ 3.60GHZ 8 18,802 150,416 Intel
36 CORE I5-9600K CPU @ 3.70GHZ 6 24,877 149,262 Intel
37 CORE I5-8400 CPU @ 2.80GHZ 6 24,086 144,516 Intel
38 RYZEN 7 2700X EIGHT-CORE 16 8,416 134,656 AMD
39 CORE I7-9700 CPU @ 3.00GHZ 8 16,586 132,688 Intel
40 RYZEN 5 5600G 12 10,834 130,008 AMD
41 RYZEN 7 5800X3D 8-CORE 16 6,999 111,984 AMD
42 CORE I7-10700T CPU @ 2.00GHZ 16 6,970 111,520 Intel
43 RYZEN 7 5800H 16 6,934 110,944 AMD
44 CORE I7-7700K CPU @ 4.20GHZ 8 13,835 110,680 Intel
45 11TH GEN CORE I5-11400 @ 2.60GHZ 12 9,073 108,876 Intel
46 CORE I7-6700K CPU @ 4.00GHZ 8 11,928 95,424 Intel
47 CORE I9-8950HK CPU @ 2.90GHZ 12 7,551 90,612 Intel
48 RYZEN 7 4800H 16 5,553 88,848 AMD
49 XEON CPU E3-1270 V5 @ 3.60GHZ 8 9,677 77,416 Intel
50 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,335 74,680 Intel
51 XEON CPU E5-1630 V3 @ 3.70GHZ 8 8,881 71,048 Intel
52 CORE I7-4770K CPU @ 3.50GHZ 8 8,477 67,816 Intel
53 11TH GEN CORE I7-1185G7 @ 3.00GHZ 8 8,309 66,472 Intel
54 XEON CPU E31245 @ 3.30GHZ 8 8,043 64,344 Intel
55 RYZEN 5 2600 SIX-CORE 12 4,947 59,364 AMD
56 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,036 56,288 Intel
57 CORE I5-8350U CPU @ 1.70GHZ 8 6,742 53,936 Intel
58 APPLE M1 PRO 10 5,363 53,630 Apple
59 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,949 47,592 Intel
60 APPLE M1 8 5,064 40,512 Apple
61 XEON CPU E5-2697 V2 @ 2.70GHZ 24 1,322 31,728 Intel