PROJECT #16992 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,011 1,056,352 AMD
2 RYZEN 7 5800X 8-CORE 16 46,225 739,600 AMD
3 RYZEN 9 5950X 16-CORE 32 13,481 431,392 AMD
4 RYZEN 7 3800X 8-CORE 16 20,735 331,760 AMD
5 CORE I9-10850K CPU @ 3.60GHZ 20 16,469 329,380 Intel
6 RYZEN 5 3600X 6-CORE 12 23,117 277,404 AMD
7 CORE I7-8700 CPU @ 3.20GHZ 12 19,762 237,144 Intel
8 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,799 235,176 Intel
9 RYZEN 5 5600X 6-CORE 12 18,785 225,420 AMD
10 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,109 199,052 Intel
11 RYZEN THREADRIPPER 3960X 24-CORE 48 3,921 188,208 AMD
12 CORE I9-7920X CPU @ 2.90GHZ 24 7,558 181,392 Intel
13 CORE I5-9600K CPU @ 3.70GHZ 6 24,877 149,262 Intel
14 RYZEN 5 3600 6-CORE 12 12,282 147,384 AMD
15 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,879 106,548 Intel
16 CORE I7-6700K CPU @ 4.00GHZ 8 11,928 95,424 Intel
17 CORE I9-8950HK CPU @ 2.90GHZ 12 7,688 92,256 Intel
18 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,335 74,680 Intel
19 CORE I7-4770K CPU @ 3.50GHZ 8 9,329 74,632 Intel
20 RYZEN 5 2600 SIX-CORE 12 4,947 59,364 AMD
21 RYZEN 7 2700X EIGHT-CORE 16 3,519 56,304 AMD
22 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,361 50,888 Intel