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PROJECT #16992 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 33,011 1,056,352 AMD
2 13TH GEN CORE I9-13900KS 32 27,343 874,976 Intel
3 RYZEN 7 5800X 8-CORE 16 46,225 739,600 AMD
4 RYZEN 9 5950X 16-CORE 32 20,353 651,296 AMD
5 RYZEN 7 7700X 8-CORE 16 38,050 608,800 AMD
6 12TH GEN CORE I9-12900K 24 20,898 501,552 Intel
7 RYZEN 7 5700G 16 31,280 500,480 AMD
8 EPYC 7V12 64-CORE 64 7,432 475,648 AMD
9 RYZEN 9 5900X 12-CORE 24 18,412 441,888 AMD
10 11TH GEN CORE I9-11900K @ 3.50GHZ 16 26,410 422,560 Intel
11 RYZEN 7 5700X 8-CORE 16 25,591 409,456 AMD
12 RYZEN 9 3900X 12-CORE 24 13,854 332,496 AMD
13 CORE I9-10850K CPU @ 3.60GHZ 20 16,469 329,380 Intel
14 11TH GEN CORE I7-11700K @ 3.60GHZ 16 18,728 299,648 Intel
15 RYZEN 7 5800X3D 8-CORE 16 18,370 293,920 AMD
16 12TH GEN CORE I7-12700K 20 14,383 287,660 Intel
17 RYZEN 7 3800X 8-CORE 16 17,524 280,384 AMD
18 RYZEN 5 3600X 6-CORE 12 23,117 277,404 AMD
19 CORE I9-7940X CPU @ 3.10GHZ 28 9,834 275,352 Intel
20 CORE I9-10900X CPU @ 3.70GHZ 20 13,670 273,400 Intel
21 RYZEN 9 3900XT 12-CORE 24 10,289 246,936 AMD
22 RYZEN 5 PRO 5650G 12 20,290 243,480 AMD
23 CORE I9-9900K CPU @ 3.60GHZ 16 15,209 243,344 Intel
24 RYZEN 9 5900HS 16 15,186 242,976 AMD
25 CORE I9-9900 CPU @ 3.10GHZ 16 14,850 237,600 Intel
26 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,799 235,176 Intel
27 RYZEN THREADRIPPER 3960X 24-CORE 48 4,534 217,632 AMD
28 RYZEN 5 5600X 6-CORE 12 17,549 210,588 AMD
29 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,109 199,052 Intel
30 CORE I7-8700 CPU @ 3.20GHZ 12 16,462 197,544 Intel
31 CORE I9-7920X CPU @ 2.90GHZ 24 7,558 181,392 Intel
32 RYZEN 7 PRO 4750G 16 11,275 180,400 AMD
33 CORE I7-8700K CPU @ 3.70GHZ 12 14,853 178,236 Intel
34 RYZEN 3 3100 4-CORE 8 22,116 176,928 AMD
35 CORE I7-9700K CPU @ 3.60GHZ 8 21,427 171,416 Intel
36 RYZEN 5 3600 6-CORE 12 14,195 170,340 AMD
37 APPLE M1 MAX 10 16,674 166,740 Apple
38 XEON CPU X5660 @ 2.80GHZ 24 6,649 159,576 Intel
39 12TH GEN CORE I5-12400 12 13,276 159,312 Intel
40 RYZEN 7 3700X 8-CORE 16 9,902 158,432 AMD
41 RYZEN 5 3500 6-CORE 6 25,781 154,686 AMD
42 XEON CPU E5-2698 V4 @ 2.20GHZ 16 9,601 153,616 Intel
43 CORE I5-9600K CPU @ 3.70GHZ 6 24,877 149,262 Intel
44 CORE I5-8400 CPU @ 2.80GHZ 6 24,086 144,516 Intel
45 CORE I7-6950X CPU @ 3.00GHZ 20 6,918 138,360 Intel
46 RYZEN 7 2700X EIGHT-CORE 16 8,416 134,656 AMD
47 CORE I7-9700 CPU @ 3.00GHZ 8 16,586 132,688 Intel
48 RYZEN 5 5600G 12 10,834 130,008 AMD
49 CORE I7-7700K CPU @ 4.20GHZ 8 14,423 115,384 Intel
50 RYZEN 7 5800H 16 6,934 110,944 AMD
51 11TH GEN CORE I5-11400 @ 2.60GHZ 12 9,073 108,876 Intel
52 CORE I7-10700T CPU @ 2.00GHZ 16 6,781 108,496 Intel
53 XEON CPU E5-2670 0 @ 2.60GHZ 32 3,341 106,912 Intel
54 CORE I7-6700K CPU @ 4.00GHZ 8 11,928 95,424 Intel
55 CORE I9-8950HK CPU @ 2.90GHZ 12 7,509 90,108 Intel
56 CORE I7-8705G CPU @ 3.10GHZ 8 11,126 89,008 Intel
57 RYZEN 7 4800H 16 5,553 88,848 AMD
58 XEON CPU E3-1270 V5 @ 3.60GHZ 8 9,677 77,416 Intel
59 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,335 74,680 Intel
60 XEON CPU E5-1630 V3 @ 3.70GHZ 8 8,881 71,048 Intel
61 11TH GEN CORE I7-1185G7 @ 3.00GHZ 8 8,309 66,472 Intel
62 XEON CPU E31245 @ 3.30GHZ 8 8,043 64,344 Intel
63 RYZEN 5 2600 SIX-CORE 12 4,947 59,364 AMD
64 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,204 57,632 Intel
65 CORE I5-8350U CPU @ 1.70GHZ 8 6,787 54,296 Intel
66 APPLE M1 8 6,560 52,480 Apple
67 CORE I7-3770 CPU @ 3.40GHZ 8 6,523 52,184 Intel
68 APPLE M1 PRO 10 5,050 50,500 Apple
69 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,949 47,592 Intel
70 XEON CPU E5-2697 V2 @ 2.70GHZ 24 1,872 44,928 Intel
71 CORE I7-4770K CPU @ 3.50GHZ 8 5,398 43,184 Intel
72 CORE I7-7700HQ CPU @ 2.80GHZ 8 5,357 42,856 Intel
73 RYZEN 5 5500U 12 3,249 38,988 AMD
74 CORE I7-2760QM CPU @ 2.40GHZ 8 3,169 25,352 Intel
75 CORE I5-10210U CPU @ 1.60GHZ 7 3,170 22,190 Intel