PROJECT #16992 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,011 1,056,352 AMD
2 RYZEN 7 5800X 8-CORE 16 46,225 739,600 AMD
3 12TH GEN CORE I9-12900K 24 20,207 484,968 Intel
4 RYZEN 7 5700X 8-CORE 16 29,607 473,712 AMD
5 RYZEN 9 5950X 16-CORE 32 13,481 431,392 AMD
6 11TH GEN CORE I9-11900K @ 3.50GHZ 16 26,410 422,560 Intel
7 11TH GEN CORE I7-11700K @ 3.60GHZ 16 25,609 409,744 Intel
8 RYZEN 7 3800X 8-CORE 16 20,735 331,760 AMD
9 CORE I9-10850K CPU @ 3.60GHZ 20 16,469 329,380 Intel
10 12TH GEN CORE I7-12700K 20 14,383 287,660 Intel
11 RYZEN 5 3600X 6-CORE 12 23,117 277,404 AMD
12 RYZEN 9 5900HS 16 15,186 242,976 AMD
13 CORE I9-9900 CPU @ 3.10GHZ 16 14,850 237,600 Intel
14 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,799 235,176 Intel
15 RYZEN 5 5600X 6-CORE 12 16,904 202,848 AMD
16 CORE I7-8700 CPU @ 3.20GHZ 12 16,710 200,520 Intel
17 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,109 199,052 Intel
18 RYZEN THREADRIPPER 3960X 24-CORE 48 3,921 188,208 AMD
19 CORE I9-7920X CPU @ 2.90GHZ 24 7,558 181,392 Intel
20 RYZEN 7 PRO 4750G 16 9,619 153,904 AMD
21 CORE I5-9600K CPU @ 3.70GHZ 6 24,877 149,262 Intel
22 XEON CPU E5-2698 V4 @ 2.20GHZ 16 9,246 147,936 Intel
23 RYZEN 7 2700X EIGHT-CORE 16 8,706 139,296 AMD
24 RYZEN 5 3600 6-CORE 12 10,973 131,676 AMD
25 RYZEN 5 5600G 12 9,622 115,464 AMD
26 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,879 106,548 Intel
27 CORE I7-6700K CPU @ 4.00GHZ 8 11,928 95,424 Intel
28 CORE I9-8950HK CPU @ 2.90GHZ 12 7,688 92,256 Intel
29 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 9,335 74,680 Intel
30 CORE I7-4770K CPU @ 3.50GHZ 8 9,329 74,632 Intel
31 11TH GEN CORE I7-1185G7 @ 3.00GHZ 8 8,309 66,472 Intel
32 XEON CPU E31245 @ 3.30GHZ 8 8,043 64,344 Intel
33 RYZEN 5 2600 SIX-CORE 12 4,947 59,364 AMD
34 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,361 50,888 Intel