PROJECT #16984 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 34,211 1,094,752 AMD
2 RYZEN 7 5800X 8-CORE 16 47,803 764,848 AMD
3 RYZEN 9 5950X 16-CORE 32 11,985 383,520 AMD
4 RYZEN 7 3800X 8-CORE 16 23,072 369,152 AMD
5 XEON CPU E5-2680 V3 @ 2.50GHZ 24 12,811 307,464 Intel
6 CORE I9-10900X CPU @ 3.70GHZ 20 14,561 291,220 Intel
7 CORE I9-10850K CPU @ 3.60GHZ 20 14,272 285,440 Intel
8 RYZEN 9 3900X 12-CORE 24 11,759 282,216 AMD
9 CORE I7-8700 CPU @ 3.20GHZ 12 19,784 237,408 Intel
10 RYZEN 7 2700X EIGHT-CORE 16 13,143 210,288 AMD
11 CORE I7-8700K CPU @ 3.70GHZ 12 15,375 184,500 Intel
12 CORE I7-9700 CPU @ 3.00GHZ 8 21,709 173,672 Intel
13 CORE I7-9700K CPU @ 3.60GHZ 8 21,663 173,304 Intel
14 CORE I5-10400 CPU @ 2.90GHZ 12 13,755 165,060 Intel
15 RYZEN THREADRIPPER 3960X 24-CORE 48 3,401 163,248 AMD
16 CORE I5-10400F CPU @ 2.90GHZ 12 12,620 151,440 Intel
17 11TH GEN CORE I5-11400 @ 2.60GHZ 12 10,185 122,220 Intel
18 CORE I7-6700K CPU @ 4.00GHZ 8 12,249 97,992 Intel
19 RYZEN 5 3600 6-CORE 12 7,395 88,740 AMD
20 CORE I7-8705G CPU @ 3.10GHZ 8 10,081 80,648 Intel
21 RYZEN 5 1600 SIX-CORE 12 5,317 63,804 AMD
22 RYZEN 5 2600 SIX-CORE 12 4,977 59,724 AMD
23 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,931 55,448 Intel