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PROJECT #16984 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Saturday, 01 April 2023 12:14:50

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Saturday, 01 April 2023 12:14:50

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 34,211 1,094,752 AMD
2 13TH GEN CORE I9-13900KS 32 27,065 866,080 Intel
3 RYZEN 9 7950X 16-CORE 32 24,520 784,640 AMD
4 RYZEN 7 5800X 8-CORE 16 46,104 737,664 AMD
5 RYZEN 7 5700G 16 42,830 685,280 AMD
6 RYZEN 7 7700X 8-CORE 16 38,340 613,440 AMD
7 RYZEN 9 5950X 16-CORE 32 18,881 604,192 AMD
8 RYZEN 9 5900X 12-CORE 24 22,686 544,464 AMD
9 RYZEN 9 3900 12-CORE 24 22,057 529,368 AMD
10 12TH GEN CORE I9-12900K 24 21,441 514,584 Intel
11 RYZEN 7 5700X 8-CORE 16 26,212 419,392 AMD
12 12TH GEN CORE I7-12700K 20 20,551 411,020 Intel
13 RYZEN 7 5800X3D 8-CORE 16 24,464 391,424 AMD
14 11TH GEN CORE I7-11700K @ 3.60GHZ 16 23,925 382,800 Intel
15 12TH GEN CORE I5-12600K 16 20,818 333,088 Intel
16 RYZEN 7 3800X 8-CORE 16 20,767 332,272 AMD
17 XEON CPU E5-2680 V3 @ 2.50GHZ 24 12,811 307,464 Intel
18 RYZEN 9 3900X 12-CORE 24 12,240 293,760 AMD
19 CORE I9-10900X CPU @ 3.70GHZ 20 14,561 291,220 Intel
20 RYZEN 5 5600G 12 24,140 289,680 AMD
21 CORE I7-10700K CPU @ 3.80GHZ 16 17,068 273,088 Intel
22 CORE I9-10850K CPU @ 3.60GHZ 20 12,833 256,660 Intel
23 RYZEN 5 5600X 6-CORE 12 21,247 254,964 AMD
24 CORE I7-8700 CPU @ 3.20GHZ 12 19,784 237,408 Intel
25 RYZEN 7 5800H 16 13,836 221,376 AMD
26 XEON CPU E5-2680 V2 @ 2.80GHZ 40 5,444 217,760 Intel
27 11TH GEN CORE I9-11900K @ 3.50GHZ 16 13,428 214,848 Intel
28 RYZEN 7 2700X EIGHT-CORE 16 12,745 203,920 AMD
29 CORE I9-9900K CPU @ 3.60GHZ 16 11,832 189,312 Intel
30 RYZEN 7 PRO 4750G 16 11,615 185,840 AMD
31 CORE I7-8700K CPU @ 3.70GHZ 12 15,375 184,500 Intel
32 APPLE M1 MAX 10 17,585 175,850 Apple
33 XEON CPU E5-2698 V4 @ 2.20GHZ 16 10,712 171,392 Intel
34 RYZEN 5 3500 6-CORE 6 28,368 170,208 AMD
35 CORE I5-10400 CPU @ 2.90GHZ 12 13,755 165,060 Intel
36 RYZEN THREADRIPPER 3960X 24-CORE 48 3,401 163,248 AMD
37 RYZEN 5 3600 6-CORE 12 13,075 156,900 AMD
38 CORE I7-9700K CPU @ 3.60GHZ 8 19,542 156,336 Intel
39 CORE I7-9700 CPU @ 3.00GHZ 8 19,181 153,448 Intel
40 CORE I5-10400F CPU @ 2.90GHZ 12 12,620 151,440 Intel
41 XEON CPU E5-2665 0 @ 2.40GHZ 32 4,196 134,272 Intel
42 CORE I5-9600K CPU @ 3.70GHZ 6 21,628 129,768 Intel
43 CORE I7-7700K CPU @ 4.20GHZ 8 15,641 125,128 Intel
44 RYZEN 7 4800H 16 7,583 121,328 AMD
45 CORE I7-8086K CPU @ 4.00GHZ 12 9,888 118,656 Intel
46 CORE I7-9750H CPU @ 2.60GHZ 12 9,156 109,872 Intel
47 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,969 107,628 Intel
48 RYZEN 5 2600X SIX-CORE 12 8,641 103,692 AMD
49 XEON CPU E5-2650 V2 @ 2.60GHZ 32 3,183 101,856 Intel
50 CORE I7-6700K CPU @ 4.00GHZ 8 12,249 97,992 Intel
51 RYZEN 7 3700X 8-CORE 16 5,772 92,352 AMD
52 CORE I7-5820K CPU @ 3.30GHZ 12 7,324 87,888 Intel
53 CORE I7-8705G CPU @ 3.10GHZ 8 10,894 87,152 Intel
54 CORE I5-8350U CPU @ 1.70GHZ 8 10,767 86,136 Intel
55 CORE I9-8950HK CPU @ 2.90GHZ 12 6,910 82,920 Intel
56 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,897 78,352 Intel
57 APPLE M1 8 8,425 67,400 Apple
58 RYZEN 5 1600 SIX-CORE 12 5,317 63,804 AMD
59 RYZEN 5 2400G 8 7,680 61,440 AMD
60 CORE I5-9400F CPU @ 2.90GHZ 6 10,137 60,822 Intel
61 RYZEN 5 2600 SIX-CORE 12 4,977 59,724 AMD
62 CORE I7-3770 CPU @ 3.40GHZ 8 6,862 54,896 Intel
63 XEON CPU E3-1275 V2 @ 3.50GHZ 8 6,827 54,616 Intel
64 APPLE M1 PRO 10 4,642 46,420 Apple
65 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,662 45,296 Intel
66 CORE I7-4770HQ CPU @ 2.20GHZ 8 4,806 38,448 Intel