PROJECT #16984 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 26 June 2022 09:57:06

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 26 June 2022 09:57:06

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 34,211 1,094,752 AMD
2 RYZEN 9 5900X 12-CORE 24 36,208 868,992 AMD
3 RYZEN 7 5800X 8-CORE 16 47,803 764,848 AMD
4 12TH GEN CORE I9-12900K 24 20,993 503,832 Intel
5 12TH GEN CORE I7-12700K 20 20,227 404,540 Intel
6 RYZEN 7 3800X 8-CORE 16 21,428 342,848 AMD
7 XEON CPU E5-2680 V3 @ 2.50GHZ 24 12,811 307,464 Intel
8 CORE I9-10900X CPU @ 3.70GHZ 20 14,561 291,220 Intel
9 RYZEN 9 5950X 16-CORE 32 9,055 289,760 AMD
10 CORE I9-10850K CPU @ 3.60GHZ 20 14,272 285,440 Intel
11 RYZEN 9 3900X 12-CORE 24 11,759 282,216 AMD
12 CORE I7-8700 CPU @ 3.20GHZ 12 19,784 237,408 Intel
13 RYZEN 7 2700X EIGHT-CORE 16 12,745 203,920 AMD
14 CORE I7-8700K CPU @ 3.70GHZ 12 15,375 184,500 Intel
15 CORE I7-9700 CPU @ 3.00GHZ 8 21,709 173,672 Intel
16 CORE I7-9700K CPU @ 3.60GHZ 8 21,663 173,304 Intel
17 RYZEN 7 4800H 16 10,817 173,072 AMD
18 XEON CPU E5-2698 V4 @ 2.20GHZ 16 10,712 171,392 Intel
19 CORE I5-10400 CPU @ 2.90GHZ 12 13,755 165,060 Intel
20 RYZEN THREADRIPPER 3960X 24-CORE 48 3,401 163,248 AMD
21 RYZEN 5 5600G 12 12,881 154,572 AMD
22 CORE I5-10400F CPU @ 2.90GHZ 12 12,620 151,440 Intel
23 11TH GEN CORE I5-11400 @ 2.60GHZ 12 10,185 122,220 Intel
24 CORE I7-9750H CPU @ 2.60GHZ 12 9,156 109,872 Intel
25 RYZEN 5 3600 6-CORE 12 8,998 107,976 AMD
26 CORE I7-6700K CPU @ 4.00GHZ 8 12,249 97,992 Intel
27 CORE I9-8950HK CPU @ 2.90GHZ 12 7,244 86,928 Intel
28 CORE I7-8705G CPU @ 3.10GHZ 8 10,081 80,648 Intel
29 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,897 78,352 Intel
30 RYZEN 5 1600 SIX-CORE 12 5,317 63,804 AMD
31 APPLE M1 PRO 10 6,280 62,800 Apple
32 RYZEN 5 2600 SIX-CORE 12 4,977 59,724 AMD
33 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,931 55,448 Intel
34 CORE I7-3770 CPU @ 3.40GHZ 8 6,862 54,896 Intel
35 XEON CPU E3-1275 V2 @ 3.50GHZ 8 6,827 54,616 Intel
36 RYZEN 7 3700X 8-CORE 16 1,849 29,584 AMD