PROJECT #16983 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 27 June 2022 11:45:24

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 27 June 2022 11:45:24

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,909 1,085,088 AMD
2 RYZEN 7 5800X 8-CORE 16 39,461 631,376 AMD
3 12TH GEN CORE I9-12900K 24 18,615 446,760 Intel
4 RYZEN 9 5950X 16-CORE 32 12,727 407,264 AMD
5 11TH GEN CORE I9-11900K @ 3.50GHZ 16 24,748 395,968 Intel
6 RYZEN 7 3800X 8-CORE 16 19,968 319,488 AMD
7 CORE I9-10850K CPU @ 3.60GHZ 20 15,726 314,520 Intel
8 11TH GEN CORE I7-11700K @ 3.60GHZ 16 19,541 312,656 Intel
9 RYZEN 7 3700X 8-CORE 16 17,721 283,536 AMD
10 RYZEN 9 3900XT 12-CORE 24 11,571 277,704 AMD
11 CORE I9-10900X CPU @ 3.70GHZ 20 13,713 274,260 Intel
12 RYZEN 5 5600X 6-CORE 12 19,003 228,036 AMD
13 CORE I7-8700 CPU @ 3.20GHZ 12 17,881 214,572 Intel
14 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,466 209,048 Intel
15 RYZEN 7 PRO 4750G 16 12,820 205,120 AMD
16 XEON W-2175 CPU @ 2.50GHZ 28 6,866 192,248 Intel
17 CORE I7-9700 CPU @ 3.00GHZ 8 22,555 180,440 Intel
18 XEON CPU E5-2698 V4 @ 2.20GHZ 16 10,217 163,472 Intel
19 CORE I7-9700K CPU @ 3.60GHZ 8 19,885 159,080 Intel
20 CORE I5-10400 CPU @ 2.90GHZ 12 13,051 156,612 Intel
21 CORE I5-8500 CPU @ 3.00GHZ 6 24,641 147,846 Intel
22 RYZEN 5 3600 6-CORE 12 11,490 137,880 AMD
23 RYZEN THREADRIPPER 3960X 24-CORE 48 2,863 137,424 AMD
24 CORE I7-5820K CPU @ 3.30GHZ 12 8,567 102,804 Intel
25 XEON CPU E5-1630 V3 @ 3.70GHZ 8 9,153 73,224 Intel
26 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,383 70,128 Intel
27 XEON W-10855M CPU @ 2.80GHZ 12 5,836 70,032 Intel
28 CORE I7-6700K CPU @ 4.00GHZ 8 8,626 69,008 Intel
29 RYZEN 9 3900X 12-CORE 24 2,828 67,872 AMD
30 CORE I9-8950HK CPU @ 2.90GHZ 12 5,628 67,536 Intel
31 CORE I7-10750H CPU @ 2.60GHZ 12 5,239 62,868 Intel
32 RYZEN 7 4700U 8 7,812 62,496 AMD
33 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,702 56,424 Intel
34 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,903 55,224 Intel
35 XEON CPU E5-1620 0 @ 3.60GHZ 8 6,473 51,784 Intel
36 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,112 48,896 Intel