PROJECT #16983 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 07 December 2022 06:13:28

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 07 December 2022 06:13:28

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,909 1,085,088 AMD
2 RYZEN 7 5800X 8-CORE 16 44,343 709,488 AMD
3 RYZEN 7 7700X 8-CORE 16 41,615 665,840 AMD
4 RYZEN 9 5950X 16-CORE 32 20,291 649,312 AMD
5 12TH GEN CORE I9-12900K 24 18,615 446,760 Intel
6 RYZEN 7 5700X 8-CORE 16 24,977 399,632 AMD
7 11TH GEN CORE I9-11900K @ 3.50GHZ 16 24,748 395,968 Intel
8 RYZEN 9 5900X 12-CORE 24 16,106 386,544 AMD
9 RYZEN 7 5700G 16 19,698 315,168 AMD
10 CORE I9-10850K CPU @ 3.60GHZ 20 15,726 314,520 Intel
11 11TH GEN CORE I7-11700K @ 3.60GHZ 16 19,431 310,896 Intel
12 RYZEN 7 3800X 8-CORE 16 19,263 308,208 AMD
13 CORE I9-10900X CPU @ 3.70GHZ 20 14,777 295,540 Intel
14 RYZEN 9 3900XT 12-CORE 24 11,571 277,704 AMD
15 RYZEN 5 5600X 6-CORE 12 19,054 228,648 AMD
16 XEON CPU E5-2680 V2 @ 2.80GHZ 40 5,501 220,040 Intel
17 CORE I7-8700 CPU @ 3.20GHZ 12 17,881 214,572 Intel
18 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,466 209,048 Intel
19 RYZEN 7 5800H 16 12,890 206,240 AMD
20 RYZEN 7 PRO 4750G 16 12,820 205,120 AMD
21 RYZEN 7 3700X 8-CORE 16 12,167 194,672 AMD
22 RYZEN 5 5600G 12 16,063 192,756 AMD
23 XEON W-2175 CPU @ 2.50GHZ 28 6,866 192,248 Intel
24 CORE I7-9700 CPU @ 3.00GHZ 8 22,555 180,440 Intel
25 XEON CPU E5-2667 V2 @ 3.30GHZ 32 5,406 172,992 Intel
26 12TH GEN CORE I9-12900H 20 8,469 169,380 Intel
27 XEON CPU E5-2697 V2 @ 2.70GHZ 24 6,772 162,528 Intel
28 CORE I7-9700K CPU @ 3.60GHZ 8 19,885 159,080 Intel
29 CORE I5-10400 CPU @ 2.90GHZ 12 13,051 156,612 Intel
30 CORE I5-8500 CPU @ 3.00GHZ 6 24,641 147,846 Intel
31 RYZEN 5 3600 6-CORE 12 12,078 144,936 AMD
32 XEON CPU E5-2698 V4 @ 2.20GHZ 16 8,936 142,976 Intel
33 XEON SILVER 4208 CPU @ 2.10GHZ 32 4,457 142,624 Intel
34 RYZEN THREADRIPPER 3960X 24-CORE 48 2,863 137,424 AMD
35 RYZEN 9 4900HS 16 8,471 135,536 AMD
36 CORE I7-7700K CPU @ 4.20GHZ 8 16,659 133,272 Intel
37 RYZEN 7 5700U 16 8,131 130,096 AMD
38 RYZEN 9 3900X 12-CORE 24 4,780 114,720 AMD
39 RYZEN 5 2600X SIX-CORE 12 8,737 104,844 AMD
40 CORE I7-5820K CPU @ 3.30GHZ 12 8,567 102,804 Intel
41 CORE I7-10700T CPU @ 2.00GHZ 16 6,072 97,152 Intel
42 CORE I5-8350U CPU @ 1.70GHZ 8 12,070 96,560 Intel
43 CORE I7-8705G CPU @ 3.10GHZ 8 11,481 91,848 Intel
44 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,506 84,048 Intel
45 CORE I9-8950HK CPU @ 2.90GHZ 12 6,547 78,564 Intel
46 XEON CPU E5-2670 0 @ 2.60GHZ 32 2,422 77,504 Intel
47 XEON CPU E5-1630 V3 @ 3.70GHZ 8 9,153 73,224 Intel
48 XEON W-10855M CPU @ 2.80GHZ 12 5,836 70,032 Intel
49 CORE I7-6700K CPU @ 4.00GHZ 8 8,616 68,928 Intel
50 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,070 65,120 Intel
51 CORE I7-10750H CPU @ 2.60GHZ 12 5,239 62,868 Intel
52 RYZEN 7 4700U 8 7,812 62,496 AMD
53 APPLE M1 MAX 10 6,186 61,860 Apple
54 CORE I5-8265U CPU @ 1.60GHZ 8 7,628 61,024 Intel
55 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,440 59,520 Intel
56 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 7,347 58,776 Intel
57 APPLE M1 8 7,092 56,736 Apple
58 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,702 56,424 Intel
59 XEON CPU E5-1620 0 @ 3.60GHZ 8 6,473 51,784 Intel
60 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,112 48,896 Intel
61 APPLE M1 PRO 10 4,877 48,770 Apple
62 XEON CPU E5-2650L V4 @ 1.70GHZ 28 1,728 48,384 Intel
63 CORE I7-4770K CPU @ 3.50GHZ 8 5,016 40,128 Intel
64 CORE I5-10210U CPU @ 1.60GHZ 7 5,190 36,330 Intel
65 CORE I7-7700HQ CPU @ 2.80GHZ 8 4,506 36,048 Intel
66 CORE I7-2760QM CPU @ 2.40GHZ 8 3,589 28,712 Intel
67 RYZEN 7 3700U 8 2,914 23,312 AMD
68 XEON CPU E3-1245 V3 @ 3.40GHZ 8 2,587 20,696 Intel