PROJECT #16983 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 27 September 2021 14:58:27

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 27 September 2021 14:58:27

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,909 1,085,088 AMD
2 RYZEN 7 5800X 8-CORE 16 30,656 490,496 AMD
3 RYZEN 9 5950X 16-CORE 32 12,657 405,024 AMD
4 CORE I9-10850K CPU @ 3.60GHZ 20 15,726 314,520 Intel
5 RYZEN 7 3700X 8-CORE 16 17,721 283,536 AMD
6 11TH GEN CORE I7-11700K @ 3.60GHZ 16 17,470 279,520 Intel
7 RYZEN 9 3900XT 12-CORE 24 11,571 277,704 AMD
8 CORE I7-8700 CPU @ 3.20GHZ 12 20,200 242,400 Intel
9 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,831 219,268 Intel
10 XEON W-2175 CPU @ 2.50GHZ 28 6,866 192,248 Intel
11 CORE I7-9700 CPU @ 3.00GHZ 8 22,555 180,440 Intel
12 CORE I7-9700K CPU @ 3.60GHZ 8 22,133 177,064 Intel
13 CORE I5-10400 CPU @ 2.90GHZ 12 12,696 152,352 Intel
14 RYZEN 5 3600 6-CORE 12 12,088 145,056 AMD
15 RYZEN THREADRIPPER 3960X 24-CORE 48 2,863 137,424 AMD
16 CORE I7-5820K CPU @ 3.30GHZ 12 8,567 102,804 Intel
17 XEON W-10855M CPU @ 2.80GHZ 12 6,102 73,224 Intel
18 CORE I9-8950HK CPU @ 2.90GHZ 12 5,628 67,536 Intel
19 CORE I7-10750H CPU @ 2.60GHZ 12 5,239 62,868 Intel
20 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,702 56,424 Intel
21 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,903 55,224 Intel
22 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,112 48,896 Intel