Research section Research projects and references

Research: CANCER Folding Project #16983

Project #16983 overview

Project Summary AI Beta

This project relates to understanding how tiny protein building blocks fold into shapes. By changing the connections and ingredients in these blocks, scientists can study how they affect folding. The goal is to learn how to design better protein-based drugs that can target cancer cells.
Automated summary; simplified and may not be fully accurate.
Source material

Official Project Description

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

Performance data

Hardware Performance for Project 16983

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:00:29

CPU PPD Averages Beta

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 7950X 16-CORE 32 36,584 1,170,688 AMD
2 RYZEN 9 3950X 16-CORE 32 33,909 1,085,088 AMD
3 RYZEN 7 7700X 8-CORE 16 39,678 634,848 AMD
4 RYZEN 9 5950X 16-CORE 32 19,684 629,888 AMD
5 RYZEN 7 7800X3D 8-CORE 16 38,454 615,264 AMD
6 RYZEN 7 5800X 8-CORE 16 38,225 611,600 AMD
7 RYZEN 7 5800X3D 8-CORE 16 31,061 496,976 AMD
8 RYZEN 7 5700G 16 28,993 463,888 AMD
9 12TH GEN CORE I9-12900K 24 18,615 446,760 Intel
10 RYZEN 7 5700X 8-CORE 16 26,902 430,432 AMD
11 RYZEN 9 5900X 12-CORE 24 16,941 406,584 AMD
12 CORE I7-7820X CPU @ 3.60GHZ 16 25,295 404,720 Intel
13 11TH GEN CORE I9-11900K @ 3.50GHZ 16 21,282 340,512 Intel
14 RYZEN 7 3800X 8-CORE 16 20,489 327,824 AMD
15 11TH GEN CORE I7-11700K @ 3.60GHZ 16 19,833 317,328 Intel
16 CORE I9-10850K CPU @ 3.60GHZ 20 15,726 314,520 Intel
17 CORE I9-10900X CPU @ 3.70GHZ 20 14,777 295,540 Intel
18 RYZEN 9 5900 12-CORE 24 11,617 278,808 AMD
19 RYZEN 9 3900XT 12-CORE 24 11,571 277,704 AMD
20 RYZEN 5 5600X 6-CORE 12 21,497 257,964 AMD
21 XEON CPU E5-2680 V2 @ 2.80GHZ 40 5,501 220,040 Intel
22 RYZEN 3 3300X 4-CORE 8 27,363 218,904 AMD
23 CORE I7-8700 CPU @ 3.20GHZ 12 17,881 214,572 Intel
24 CORE I9-7940X CPU @ 3.10GHZ 28 7,623 213,444 Intel
25 RYZEN 7 3700X 8-CORE 16 13,235 211,760 AMD
26 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,466 209,048 Intel
27 RYZEN 7 PRO 4750G 16 12,820 205,120 AMD
28 RYZEN 7 5800H 16 12,233 195,728 AMD
29 RYZEN 5 5600G 12 16,063 192,756 AMD
30 XEON W-2175 CPU @ 2.50GHZ 28 6,866 192,248 Intel
31 RYZEN 5 3500 6-CORE 6 29,645 177,870 AMD
32 CORE I7-9700 CPU @ 3.00GHZ 8 21,825 174,600 Intel
33 XEON CPU E5-2667 V2 @ 3.30GHZ 32 5,406 172,992 Intel
34 12TH GEN CORE I9-12900H 20 8,469 169,380 Intel
35 XEON CPU E5-2697 V2 @ 2.70GHZ 24 6,772 162,528 Intel
36 RYZEN 5 3600 6-CORE 12 13,296 159,552 AMD
37 CORE I5-10400 CPU @ 2.90GHZ 12 13,051 156,612 Intel
38 RYZEN 9 3900X 12-CORE 24 6,188 148,512 AMD
39 CORE I5-8500 CPU @ 3.00GHZ 6 24,641 147,846 Intel
40 XEON CPU E5-2698 V4 @ 2.20GHZ 16 8,936 142,976 Intel
41 XEON SILVER 4208 CPU @ 2.10GHZ 32 4,457 142,624 Intel
42 RYZEN THREADRIPPER 3960X 24-CORE 48 2,863 137,424 AMD
43 RYZEN 9 4900HS 16 8,471 135,536 AMD
44 CORE I9-9900K CPU @ 3.60GHZ 16 8,457 135,312 Intel
45 CORE I7-9700K CPU @ 3.60GHZ 8 16,874 134,992 Intel
46 RYZEN 7 5700U 16 8,131 130,096 AMD
47 CORE I7-7700K CPU @ 4.20GHZ 8 15,442 123,536 Intel
48 CORE I7-5930K CPU @ 3.50GHZ 12 10,227 122,724 Intel
49 12TH GEN CORE I3-12100F 8 13,696 109,568 Intel
50 RYZEN 5 2600X SIX-CORE 12 8,737 104,844 AMD
51 CORE I7-5820K CPU @ 3.30GHZ 12 8,694 104,328 Intel
52 RYZEN 5 2600 SIX-CORE 12 8,649 103,788 AMD
53 CORE I7-10700T CPU @ 2.00GHZ 16 5,980 95,680 Intel
54 CORE I7-8705G CPU @ 3.10GHZ 8 11,481 91,848 Intel
55 XEON CPU E3-1270 V5 @ 3.60GHZ 8 10,506 84,048 Intel
56 CORE I9-8950HK CPU @ 2.90GHZ 12 6,642 79,704 Intel
57 XEON CPU E5-2670 0 @ 2.60GHZ 32 2,422 77,504 Intel
58 XEON CPU E5-1630 V3 @ 3.70GHZ 8 9,153 73,224 Intel
59 CORE I7-6700K CPU @ 4.00GHZ 8 8,616 68,928 Intel
60 XEON W-10855M CPU @ 2.80GHZ 12 5,652 67,824 Intel
61 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,070 65,120 Intel
62 CORE I7-10750H CPU @ 2.60GHZ 12 5,239 62,868 Intel
63 RYZEN 7 4700U 8 7,812 62,496 AMD
64 APPLE M1 MAX 10 6,186 61,860 Apple
65 CORE I5-8265U CPU @ 1.60GHZ 8 7,628 61,024 Intel
66 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,545 60,360 Intel
67 CORE I7-4770 CPU @ 3.40GHZ 8 7,507 60,056 Intel
68 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 7,347 58,776 Intel
69 CORE I7-3770K CPU @ 3.50GHZ 8 7,105 56,840 Intel
70 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,702 56,424 Intel
71 APPLE M1 8 6,790 54,320 Apple
72 CORE I5-8350U CPU @ 1.70GHZ 8 6,551 52,408 Intel
73 XEON CPU E5-1620 0 @ 3.60GHZ 8 6,473 51,784 Intel
74 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,112 48,896 Intel
75 XEON CPU E5-2650L V4 @ 1.70GHZ 28 1,728 48,384 Intel
76 APPLE M1 PRO 10 4,476 44,760 Apple
77 XEON CPU E3-1245 V3 @ 3.40GHZ 8 5,542 44,336 Intel
78 CORE I7-4770K CPU @ 3.50GHZ 8 5,016 40,128 Intel
79 CORE I7-7700HQ CPU @ 2.80GHZ 8 3,666 29,328 Intel
80 CORE I7-2760QM CPU @ 2.40GHZ 8 3,589 28,712 Intel
81 CORE I5-10210U CPU @ 1.60GHZ 7 3,733 26,131 Intel
82 RYZEN 7 3700U 8 2,914 23,312 AMD