PROJECT #16983 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Saturday, 15 January 2022 23:40:54

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Saturday, 15 January 2022 23:40:54

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 33,909 1,085,088 AMD
2 RYZEN 7 5800X 8-CORE 16 39,461 631,376 AMD
3 RYZEN 9 5950X 16-CORE 32 12,657 405,024 AMD
4 CORE I9-10850K CPU @ 3.60GHZ 20 15,726 314,520 Intel
5 RYZEN 7 3800X 8-CORE 16 19,018 304,288 AMD
6 RYZEN 7 3700X 8-CORE 16 17,721 283,536 AMD
7 11TH GEN CORE I7-11700K @ 3.60GHZ 16 17,470 279,520 Intel
8 RYZEN 9 3900XT 12-CORE 24 11,571 277,704 AMD
9 CORE I9-10900X CPU @ 3.70GHZ 20 13,713 274,260 Intel
10 RYZEN 5 5600X 6-CORE 12 19,003 228,036 AMD
11 CORE I7-8700 CPU @ 3.20GHZ 12 17,881 214,572 Intel
12 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,466 209,048 Intel
13 XEON W-2175 CPU @ 2.50GHZ 28 6,866 192,248 Intel
14 CORE I7-9700 CPU @ 3.00GHZ 8 22,555 180,440 Intel
15 CORE I7-9700K CPU @ 3.60GHZ 8 22,133 177,064 Intel
16 CORE I5-10400 CPU @ 2.90GHZ 12 13,051 156,612 Intel
17 RYZEN 5 3600 6-CORE 12 12,077 144,924 AMD
18 RYZEN THREADRIPPER 3960X 24-CORE 48 2,863 137,424 AMD
19 CORE I7-5820K CPU @ 3.30GHZ 12 8,567 102,804 Intel
20 XEON W-10855M CPU @ 2.80GHZ 12 5,836 70,032 Intel
21 CORE I7-6700K CPU @ 4.00GHZ 8 8,626 69,008 Intel
22 CORE I9-8950HK CPU @ 2.90GHZ 12 5,628 67,536 Intel
23 CORE I7-10750H CPU @ 2.60GHZ 12 5,239 62,868 Intel
24 RYZEN 7 4700U 8 7,812 62,496 AMD
25 XEON CPU E5-2620 0 @ 2.00GHZ 12 4,702 56,424 Intel
26 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,903 55,224 Intel
27 XEON CPU E5-1620 0 @ 3.60GHZ 8 6,473 51,784 Intel
28 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,112 48,896 Intel