PROJECT #16988 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 32,308 1,033,856 AMD
2 RYZEN 7 5800X 8-CORE 16 38,474 615,584 AMD
3 RYZEN 9 5950X 16-CORE 32 15,574 498,368 AMD
4 11TH GEN CORE I9-11900K @ 3.50GHZ 16 25,622 409,952 Intel
5 RYZEN 7 3800X 8-CORE 16 21,701 347,216 AMD
6 RYZEN 9 5900X 12-CORE 24 14,141 339,384 AMD
7 XEON CPU E5-2680 V3 @ 2.50GHZ 24 13,417 322,008 Intel
8 CORE I9-10900X CPU @ 3.70GHZ 20 14,844 296,880 Intel
9 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,089 277,068 Intel
10 CORE I9-9900K CPU @ 3.60GHZ 16 15,988 255,808 Intel
11 CORE I7-8700 CPU @ 3.20GHZ 12 20,155 241,860 Intel
12 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,964 194,992 Intel
13 RYZEN 5 3600 6-CORE 12 14,623 175,476 AMD
14 RYZEN 7 PRO 4750G 16 10,108 161,728 AMD
15 CORE I5-9600KF CPU @ 3.70GHZ 6 26,884 161,304 Intel
16 CORE I5-10400 CPU @ 2.90GHZ 12 11,159 133,908 Intel
17 RYZEN 5 2600 SIX-CORE 12 8,520 102,240 AMD
18 CORE I7-5820K CPU @ 3.30GHZ 12 8,149 97,788 Intel
19 XEON CPU E5-2620 0 @ 2.00GHZ 12 6,869 82,428 Intel
20 CORE I7-6700K CPU @ 4.00GHZ 8 9,453 75,624 Intel
21 CORE I7-6700HQ CPU @ 2.60GHZ 8 9,108 72,864 Intel
22 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,455 71,280 Intel
23 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,422 59,376 Intel
24 RYZEN 5 3500U 8 1,743 13,944 AMD