PROJECT #16964 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 15 April 2021 20:18:09

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 15 April 2021 20:18:09

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 25,529 408,464 AMD
2 RYZEN 9 3900XT 12-CORE 24 15,470 371,280 AMD
3 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,504 360,192 AMD
4 RYZEN 9 3900 12-CORE 24 13,644 327,456 AMD
5 CORE I9-10900KF CPU @ 3.70GHZ 20 15,447 308,940 Intel
6 CORE I7-10875H CPU @ 2.30GHZ 16 18,017 288,272 Intel
7 RYZEN 5 5600X 6-CORE 12 20,905 250,860 AMD
8 RYZEN 7 3700X 8-CORE 16 15,446 247,136 AMD
9 CORE I9-10900X CPU @ 3.70GHZ 20 8,949 178,980 Intel
10 RYZEN 5 3600 6-CORE 12 14,264 171,168 AMD
11 RYZEN 7 2700X EIGHT-CORE 16 9,594 153,504 AMD
12 RYZEN 9 5900X 12-CORE 24 5,413 129,912 AMD
13 XEON CPU E5-2680 V3 @ 2.50GHZ 24 4,794 115,056 Intel
14 CORE I3-9100F CPU @ 3.60GHZ 4 27,208 108,832 Intel
15 RYZEN 5 2600 SIX-CORE 12 7,499 89,988 AMD
16 CORE I7-6700K CPU @ 4.00GHZ 8 9,280 74,240 Intel
17 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,990 63,920 Intel
18 CORE I7-4790T CPU @ 2.70GHZ 8 6,553 52,424 Intel
19 CORE I5-8250U CPU @ 1.60GHZ 8 6,483 51,864 Intel
20 PHENOM II X6 1090T 6 6,189 37,134 AMD
21 RYZEN 5 3500U 8 2,755 22,040 AMD