PROJECT #16968 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 03 December 2021 04:36:10

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Friday, 03 December 2021 04:36:10

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 25,601 819,232 AMD
2 RYZEN 9 5950X 16-CORE 32 21,635 692,320 AMD
3 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,549 362,352 AMD
4 RYZEN 7 5800X 8-CORE 16 21,511 344,176 AMD
5 RYZEN 9 3900XT 12-CORE 24 14,061 337,464 AMD
6 RYZEN 9 5900X 12-CORE 24 13,179 316,296 AMD
7 RYZEN 9 3900 12-CORE 24 13,098 314,352 AMD
8 11TH GEN CORE I7-11700K @ 3.60GHZ 16 18,698 299,168 Intel
9 CORE I9-10900X CPU @ 3.70GHZ 20 12,457 249,140 Intel
10 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,313 247,512 Intel
11 RYZEN 5 5600X 6-CORE 12 19,467 233,604 AMD
12 XEON CPU E5-2680 V4 @ 2.40GHZ 28 8,219 230,132 Intel
13 XEON CPU E5-2690 V4 @ 2.60GHZ 28 8,154 228,312 Intel
14 RYZEN 7 3700X 8-CORE 16 13,405 214,480 AMD
15 RYZEN 7 3800X 8-CORE 16 12,305 196,880 AMD
16 RYZEN 5 3600X 6-CORE 12 14,111 169,332 AMD
17 CORE I7-9700K CPU @ 3.60GHZ 8 20,986 167,888 Intel
18 RYZEN 7 4800H 16 10,394 166,304 AMD
19 CORE I7-10700K CPU @ 3.80GHZ 16 9,313 149,008 Intel
20 RYZEN 7 2700X EIGHT-CORE 16 9,072 145,152 AMD
21 RYZEN 5 3600 6-CORE 12 11,742 140,904 AMD
22 CORE I7-10870H CPU @ 2.20GHZ 16 7,339 117,424 Intel
23 RYZEN 3 3100 4-CORE 8 14,097 112,776 AMD
24 CORE I5-10400F CPU @ 2.90GHZ 12 9,110 109,320 Intel
25 CORE I7-9700T CPU @ 2.00GHZ 8 13,581 108,648 Intel
26 CORE I9-9900K CPU @ 3.60GHZ 16 6,790 108,640 Intel
27 CORE I7-6700K CPU @ 4.00GHZ 8 12,677 101,416 Intel
28 RYZEN 5 2600 SIX-CORE 12 7,600 91,200 AMD
29 RYZEN THREADRIPPER 2950X 16-CORE 32 2,384 76,288 AMD
30 11TH GEN CORE I5-11400 @ 2.60GHZ 12 6,022 72,264 Intel
31 CORE I5-10300H CPU @ 2.50GHZ 8 8,199 65,592 Intel
32 XEON W-10855M CPU @ 2.80GHZ 12 5,419 65,028 Intel
33 CORE I7-4790K CPU @ 4.00GHZ 8 7,469 59,752 Intel
34 CORE I5-8300H CPU @ 2.30GHZ 8 7,421 59,368 Intel
35 CORE I5-9300H CPU @ 2.40GHZ 8 6,874 54,992 Intel
36 CORE I7-6820HQ CPU @ 2.70GHZ 8 6,548 52,384 Intel
37 CORE I7-8550U CPU @ 1.80GHZ 8 5,517 44,136 Intel
38 XEON CPU E3-1241 V3 @ 3.50GHZ 8 4,418 35,344 Intel
39 CORE I7-3610QM CPU @ 2.30GHZ 8 3,435 27,480 Intel
40 PHENOM II X6 1090T 6 4,523 27,138 AMD