PROJECT #16990 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 7 5800X 8-CORE 16 40,186 642,976 AMD
2 RYZEN 9 3950X 16-CORE 32 19,720 631,040 AMD
3 RYZEN 9 5950X 16-CORE 32 13,550 433,600 AMD
4 11TH GEN CORE I9-11900K @ 3.50GHZ 16 24,034 384,544 Intel
5 RYZEN 7 3800X 8-CORE 16 21,490 343,840 AMD
6 CORE I9-10900X CPU @ 3.70GHZ 20 12,575 251,500 Intel
7 XEON CPU E5-2690 V4 @ 2.60GHZ 28 8,972 251,216 Intel
8 CORE I9-9900 CPU @ 3.10GHZ 16 14,965 239,440 Intel
9 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,946 238,704 Intel
10 CORE I7-8700 CPU @ 3.20GHZ 12 19,871 238,452 Intel
11 RYZEN 7 3700X 8-CORE 16 12,265 196,240 AMD
12 RYZEN 5 5600X 6-CORE 12 15,604 187,248 AMD
13 CORE I7-10700 CPU @ 2.90GHZ 16 10,649 170,384 Intel
14 RYZEN 7 2700X EIGHT-CORE 16 10,587 169,392 AMD
15 11TH GEN CORE I7-11800H @ 2.30GHZ 16 10,480 167,680 Intel
16 CORE I5-10400 CPU @ 2.90GHZ 12 12,702 152,424 Intel
17 RYZEN 5 3600 6-CORE 12 11,506 138,072 AMD
18 CORE I7-6700K CPU @ 4.00GHZ 8 10,956 87,648 Intel
19 RYZEN 5 1600 SIX-CORE 12 7,227 86,724 AMD
20 CORE I7-8705G CPU @ 3.10GHZ 8 10,687 85,496 Intel
21 EPYC 7251 8-CORE 16 4,753 76,048 AMD
22 11TH GEN CORE I7-11370H @ 3.30GHZ 8 8,943 71,544 Intel
23 CORE I7-6700 CPU @ 3.40GHZ 8 8,211 65,688 Intel
24 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,698 61,584 Intel
25 CORE I3-10100 CPU @ 3.60GHZ 8 6,930 55,440 Intel
26 XEON CPU E3-1245 V2 @ 3.40GHZ 8 5,840 46,720 Intel
27 CORE I7-10610U CPU @ 1.80GHZ 8 5,299 42,392 Intel
28 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 5,288 42,304 Intel
29 CORE I5-8259U CPU @ 2.30GHZ 8 4,805 38,440 Intel
30 CORE I7-4770K CPU @ 3.50GHZ 8 4,792 38,336 Intel
31 CORE I7-7700HQ CPU @ 2.80GHZ 8 3,828 30,624 Intel
32 XEON CPU E31245 @ 3.30GHZ 8 3,618 28,944 Intel
33 CORE I5-9300H CPU @ 2.40GHZ 8 2,971 23,768 Intel