PROJECT #16985 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 28 September 2021 06:02:47

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 28 September 2021 06:02:47

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 25,784 825,088 AMD
2 RYZEN 7 5800X 8-CORE 16 39,851 637,616 AMD
3 RYZEN 9 5950X 16-CORE 32 11,932 381,824 AMD
4 RYZEN 7 3800X 8-CORE 16 20,627 330,032 AMD
5 XEON CPU E5-2680 V3 @ 2.50GHZ 24 13,498 323,952 Intel
6 CORE I9-10850K CPU @ 3.60GHZ 20 15,127 302,540 Intel
7 CORE I9-10900X CPU @ 3.70GHZ 20 14,305 286,100 Intel
8 CORE I7-8700 CPU @ 3.20GHZ 12 19,954 239,448 Intel
9 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,727 216,356 Intel
10 RYZEN THREADRIPPER 3960X 24-CORE 48 4,336 208,128 AMD
11 RYZEN 7 2700X EIGHT-CORE 16 10,280 164,480 AMD
12 CORE I5-10400 CPU @ 2.90GHZ 12 13,246 158,952 Intel
13 CORE I7-5820K CPU @ 3.30GHZ 12 9,926 119,112 Intel
14 CORE I7-6700K CPU @ 4.00GHZ 8 13,314 106,512 Intel
15 CORE I7-8705G CPU @ 3.10GHZ 8 10,618 84,944 Intel
16 CORE I3-10100 CPU @ 3.60GHZ 8 10,553 84,424 Intel
17 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,459 59,672 Intel
18 CORE I7-10750H CPU @ 2.60GHZ 12 4,929 59,148 Intel
19 CORE I9-8950HK CPU @ 2.90GHZ 12 4,126 49,512 Intel