PROJECT #16985 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 04 December 2022 18:13:26

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 04 December 2022 18:13:26

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 CORE I7-4770HQ CPU @ 2.20GHZ 8 1,930,838 15,446,704 Intel
2 RYZEN 9 3950X 16-CORE 32 24,563 786,016 AMD
3 RYZEN 7 5800X 8-CORE 16 33,308 532,928 AMD
4 RYZEN 9 5950X 16-CORE 32 15,288 489,216 AMD
5 12TH GEN CORE I9-12900K 24 20,374 488,976 Intel
6 RYZEN 7 7700X 8-CORE 16 30,560 488,960 AMD
7 RYZEN 7 5800X3D 8-CORE 16 29,905 478,480 AMD
8 RYZEN 7 5700X 8-CORE 16 27,895 446,320 AMD
9 RYZEN 9 5900X 12-CORE 24 18,540 444,960 AMD
10 11TH GEN CORE I7-11700K @ 3.60GHZ 16 24,148 386,368 Intel
11 XEON CPU E5-2680 V3 @ 2.50GHZ 24 13,498 323,952 Intel
12 RYZEN 7 3800X 8-CORE 16 19,779 316,464 AMD
13 12TH GEN CORE I7-12700K 20 15,128 302,560 Intel
14 CORE I9-10900X CPU @ 3.70GHZ 20 14,305 286,100 Intel
15 CORE I9-10850K CPU @ 3.60GHZ 20 14,149 282,980 Intel
16 RYZEN 9 3900X 12-CORE 24 11,677 280,248 AMD
17 RYZEN 5 5600X 6-CORE 12 22,902 274,824 AMD
18 RYZEN 5 PRO 5650G 12 20,496 245,952 AMD
19 RYZEN 5 5600G 12 19,143 229,716 AMD
20 CORE I7-8700 CPU @ 3.20GHZ 12 18,458 221,496 Intel
21 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,727 216,356 Intel
22 RYZEN THREADRIPPER 3960X 24-CORE 48 4,336 208,128 AMD
23 CORE I9-9900K CPU @ 3.60GHZ 16 12,643 202,288 Intel
24 CORE I7-9700K CPU @ 3.60GHZ 8 24,974 199,792 Intel
25 XEON GOLD 6128 CPU @ 3.40GHZ 12 16,566 198,792 Intel
26 RYZEN 7 5700G 16 11,784 188,544 AMD
27 12TH GEN CORE I3-12100F 8 22,556 180,448 Intel
28 APPLE M1 MAX 10 17,974 179,740 Apple
29 RYZEN 7 3700X 8-CORE 16 11,140 178,240 AMD
30 RYZEN 7 PRO 4750G 16 10,419 166,704 AMD
31 RYZEN 7 2700X EIGHT-CORE 16 10,280 164,480 AMD
32 11TH GEN CORE I5-11400 @ 2.60GHZ 12 11,276 135,312 Intel
33 RYZEN 5 3600 6-CORE 12 11,170 134,040 AMD
34 11TH GEN CORE I9-11900F @ 2.50GHZ 16 8,321 133,136 Intel
35 XEON CPU E5-2650 V2 @ 2.60GHZ 32 3,736 119,552 Intel
36 RYZEN 5 2600X SIX-CORE 12 9,347 112,164 AMD
37 CORE I7-7700K CPU @ 4.20GHZ 8 13,967 111,736 Intel
38 CORE I7-6700K CPU @ 4.00GHZ 8 13,314 106,512 Intel
39 CORE I5-10400 CPU @ 2.90GHZ 12 8,137 97,644 Intel
40 CORE I7-10700T CPU @ 2.00GHZ 16 6,031 96,496 Intel
41 CORE I7-8705G CPU @ 3.10GHZ 8 10,952 87,616 Intel
42 CORE I3-10100 CPU @ 3.60GHZ 8 10,553 84,424 Intel
43 CORE I5-8600T CPU @ 2.30GHZ 6 11,981 71,886 Intel
44 APPLE M1 8 8,857 70,856 Apple
45 EPYC 7251 8-CORE 16 4,376 70,016 AMD
46 CORE I7-4770K CPU @ 3.50GHZ 8 8,689 69,512 Intel
47 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,340 69,440 Intel
48 CORE I7-10750H CPU @ 2.60GHZ 12 4,929 59,148 Intel
49 XEON CPU E3-1270 V5 @ 3.60GHZ 8 7,275 58,200 Intel
50 CORE I7-5820K CPU @ 3.30GHZ 12 4,826 57,912 Intel
51 CORE I9-8950HK CPU @ 2.90GHZ 12 4,126 49,512 Intel
52 APPLE M1 PRO 10 4,734 47,340 Apple
53 CORE I7-3770 CPU @ 3.40GHZ 8 5,747 45,976 Intel
54 CORE I5-10210U CPU @ 1.60GHZ 7 5,867 41,069 Intel
55 XEON CPU E31245 @ 3.30GHZ 8 3,650 29,200 Intel
56 XEON CPU W3550 @ 3.07GHZ 8 3,550 28,400 Intel