PROJECT #16985 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Saturday, 01 April 2023 12:14:50

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Saturday, 01 April 2023 12:14:50

Rank Project	CPU Model	Logical Processors (LP)	PPD-PLP AVG PPD per 1 LP	ALL LP-PPD (Estimated)	Make
1	CORE I7-4770HQ CPU @ 2.20GHZ	8	1,930,838	15,446,704	Intel
2	RYZEN 9 3950X 16-CORE	32	24,563	786,016	AMD
3	12TH GEN CORE I9-12900K	24	27,270	654,480	Intel
4	RYZEN 7 7700X 8-CORE	16	37,602	601,632	AMD
5	RYZEN 7 5800X 8-CORE	16	33,308	532,928	AMD
6	RYZEN 9 5950X 16-CORE	32	16,349	523,168	AMD
7	RYZEN 7 5800X3D 8-CORE	16	29,905	478,480	AMD
8	RYZEN 7 5700X 8-CORE	16	27,782	444,512	AMD
9	RYZEN 9 5900X 12-CORE	24	18,343	440,232	AMD
10	11TH GEN CORE I7-11700K @ 3.60GHZ	16	24,148	386,368	Intel
11	RYZEN 7 5700G	16	22,303	356,848	AMD
12	XEON CPU E5-2680 V3 @ 2.50GHZ	24	13,498	323,952	Intel
13	RYZEN 7 3800X 8-CORE	16	19,880	318,080	AMD
14	12TH GEN CORE I7-12700K	20	15,128	302,560	Intel
15	CORE I9-10900X CPU @ 3.70GHZ	20	14,305	286,100	Intel
16	CORE I9-10850K CPU @ 3.60GHZ	20	14,149	282,980	Intel
17	RYZEN 9 3900X 12-CORE	24	11,677	280,248	AMD
18	RYZEN 5 5600X 6-CORE	12	22,569	270,828	AMD
19	RYZEN 5 PRO 5650G	12	20,496	245,952	AMD
20	CORE I9-9900K CPU @ 3.60GHZ	16	14,968	239,488	Intel
21	RYZEN 5 5600G	12	19,143	229,716	AMD
22	CORE I7-8700 CPU @ 3.20GHZ	12	18,458	221,496	Intel
23	XEON CPU E5-2690 V4 @ 2.60GHZ	28	7,727	216,356	Intel
24	RYZEN THREADRIPPER 3960X 24-CORE	48	4,336	208,128	AMD
25	XEON GOLD 6128 CPU @ 3.40GHZ	12	16,566	198,792	Intel
26	CORE I7-9700K CPU @ 3.60GHZ	8	24,699	197,592	Intel
27	APPLE M1 MAX	10	17,974	179,740	Apple
28	RYZEN 7 3700X 8-CORE	16	10,506	168,096	AMD
29	RYZEN 7 PRO 4750G	16	10,302	164,832	AMD
30	RYZEN 7 2700X EIGHT-CORE	16	10,280	164,480	AMD
31	12TH GEN CORE I3-12100F	8	19,172	153,376	Intel
32	RYZEN 5 3600 6-CORE	12	11,760	141,120	AMD
33	CORE I5-9600K CPU @ 3.70GHZ	6	22,587	135,522	Intel
34	11TH GEN CORE I5-11400 @ 2.60GHZ	12	11,276	135,312	Intel
35	11TH GEN CORE I9-11900F @ 2.50GHZ	16	8,321	133,136	Intel
36	XEON CPU E5-2650 V2 @ 2.60GHZ	32	3,736	119,552	Intel
37	CORE I7-7700K CPU @ 4.20GHZ	8	14,170	113,360	Intel
38	RYZEN 5 2600X SIX-CORE	12	9,347	112,164	AMD
39	RYZEN 5 1600 SIX-CORE	12	8,979	107,748	AMD
40	CORE I5-10400 CPU @ 2.90GHZ	12	8,137	97,644	Intel
41	CORE I7-10700T CPU @ 2.00GHZ	16	6,031	96,496	Intel
42	CORE I7-8705G CPU @ 3.10GHZ	8	10,952	87,616	Intel
43	CORE I3-10100 CPU @ 3.60GHZ	8	10,553	84,424	Intel
44	CORE I5-8600T CPU @ 2.30GHZ	6	11,981	71,886	Intel
45	EPYC 7251 8-CORE	16	4,376	70,016	AMD
46	CORE I7-4770K CPU @ 3.50GHZ	8	8,689	69,512	Intel
47	XEON CPU E5-2680 0 @ 2.70GHZ	16	4,340	69,440	Intel
48	APPLE M1	8	8,438	67,504	Apple
49	CORE I9-8950HK CPU @ 2.90GHZ	12	5,375	64,500	Intel
50	CORE I7-6700K CPU @ 4.00GHZ	8	8,040	64,320	Intel
51	CORE I7-10750H CPU @ 2.60GHZ	12	4,929	59,148	Intel
52	XEON CPU E3-1270 V5 @ 3.60GHZ	8	7,275	58,200	Intel
53	CORE I7-5820K CPU @ 3.30GHZ	12	4,826	57,912	Intel
54	APPLE M1 PRO	10	4,734	47,340	Apple
55	CORE I7-3770 CPU @ 3.40GHZ	8	5,747	45,976	Intel
56	CORE I7-7700HQ CPU @ 2.80GHZ	8	5,641	45,128	Intel
57	CORE I5-10210U CPU @ 1.60GHZ	7	5,867	41,069	Intel
58	XEON CPU E31245 @ 3.30GHZ	8	3,650	29,200	Intel
59	XEON CPU W3550 @ 3.07GHZ	8	3,550	28,400	Intel