PROJECT #16985 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins.

We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 23,400

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 30 June 2022 00:50:01

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 CORE I7-4770HQ CPU @ 2.20GHZ 8 1,930,838 15,446,704 Intel
2 RYZEN 9 5900X 12-CORE 24 42,011 1,008,264 AMD
3 RYZEN 9 3950X 16-CORE 32 25,784 825,088 AMD
4 RYZEN 7 5800X 8-CORE 16 39,851 637,616 AMD
5 12TH GEN CORE I7-12700K 20 22,148 442,960 Intel
6 11TH GEN CORE I7-11700K @ 3.60GHZ 16 24,148 386,368 Intel
7 RYZEN 7 3800X 8-CORE 16 20,627 330,032 AMD
8 XEON CPU E5-2680 V3 @ 2.50GHZ 24 13,498 323,952 Intel
9 CORE I9-10850K CPU @ 3.60GHZ 20 15,127 302,540 Intel
10 CORE I9-10900X CPU @ 3.70GHZ 20 14,305 286,100 Intel
11 RYZEN 9 5950X 16-CORE 32 8,812 281,984 AMD
12 CORE I7-8700 CPU @ 3.20GHZ 12 19,954 239,448 Intel
13 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,727 216,356 Intel
14 RYZEN THREADRIPPER 3960X 24-CORE 48 4,336 208,128 AMD
15 RYZEN 7 5700G 16 11,784 188,544 AMD
16 RYZEN 5 5600X 6-CORE 12 14,916 178,992 AMD
17 RYZEN 7 PRO 4750G 16 11,051 176,816 AMD
18 RYZEN 7 2700X EIGHT-CORE 16 10,280 164,480 AMD
19 CORE I5-10400 CPU @ 2.90GHZ 12 13,246 158,952 Intel
20 RYZEN 5 3600 6-CORE 12 11,294 135,528 AMD
21 CORE I7-5820K CPU @ 3.30GHZ 12 9,926 119,112 Intel
22 CORE I7-6700K CPU @ 4.00GHZ 8 13,314 106,512 Intel
23 CORE I7-8705G CPU @ 3.10GHZ 8 10,618 84,944 Intel
24 CORE I3-10100 CPU @ 3.60GHZ 8 10,553 84,424 Intel
25 CORE I5-8600T CPU @ 2.30GHZ 6 11,981 71,886 Intel
26 EPYC 7251 8-CORE 16 4,376 70,016 AMD
27 CORE I7-10750H CPU @ 2.60GHZ 12 4,929 59,148 Intel
28 CORE I9-8950HK CPU @ 2.90GHZ 12 4,126 49,512 Intel
29 APPLE M1 PRO 10 4,734 47,340 Apple
30 CORE I7-3770 CPU @ 3.40GHZ 8 5,747 45,976 Intel
31 CORE I5-10210U CPU @ 1.60GHZ 7 5,867 41,069 Intel
32 XEON CPU E31245 @ 3.30GHZ 8 3,650 29,200 Intel
33 XEON CPU W3550 @ 3.07GHZ 8 3,550 28,400 Intel