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Research: MYOSINS Folding Project #17437

Project #17437 overview

Project Summary AI Beta

This project studies myosins, proteins that power movement in our bodies, from muscle contractions to cell functions. Scientists want to understand how drugs can fix problems with myosins that cause heart diseases like cardiomyopathies and heart failure.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Artur Meller
Institution
Washington University in St. Louis

Work unit

Atoms
171,004
Core
GRO_A7
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 17437

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:57:58

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 5950X 16-CORE 32 32,192 1,030,144 AMD
2 RYZEN 9 3950X 16-CORE 32 23,226 743,232 AMD
3 RYZEN 9 3900XT 12-CORE 24 16,901 405,624 AMD
4 RYZEN 9 3900 12-CORE 24 15,981 383,544 AMD
5 RYZEN 7 3800X 8-CORE 16 18,545 296,720 AMD
6 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,528 210,784 Intel
7 11TH GEN CORE I7-11700K @ 3.60GHZ 16 12,484 199,744 Intel
8 CORE I9-10900X CPU @ 3.70GHZ 20 9,026 180,520 Intel
9 11TH GEN CORE I9-11900K @ 3.50GHZ 16 9,267 148,272 Intel
10 RYZEN 5 3600 6-CORE 12 10,965 131,580 AMD
11 CORE I7-8700 CPU @ 3.20GHZ 12 9,186 110,232 Intel
12 RYZEN 5 5600X 6-CORE 12 9,028 108,336 AMD
13 CORE I7-10870H CPU @ 2.20GHZ 16 4,888 78,208 Intel
14 XEON CPU E5-2690 V2 @ 3.00GHZ 20 3,644 72,880 Intel
15 CORE I7-10750H CPU @ 2.60GHZ 12 4,053 48,636 Intel
16 RYZEN 5 2600 SIX-CORE 12 3,779 45,348 AMD
17 XEON W-10855M CPU @ 2.80GHZ 12 3,632 43,584 Intel
18 CORE I5-8300H CPU @ 2.30GHZ 8 4,956 39,648 Intel
19 CORE I5-7600 CPU @ 3.50GHZ 4 9,196 36,784 Intel
20 CORE I5-4590 CPU @ 3.30GHZ 4 7,343 29,372 Intel
21 CORE I5-4570S CPU @ 2.90GHZ 4 7,132 28,528 Intel
22 CORE I5-6600K CPU @ 3.50GHZ 4 5,854 23,416 Intel
23 CORE I5-7200U CPU @ 2.50GHZ 4 2,041 8,164 Intel
24 CORE I3-3110M CPU @ 2.40GHZ 4 1,890 7,560 Intel
25 CORE I5-4690K CPU @ 3.50GHZ 4 889 3,556 Intel
26 FX-8350 EIGHT-CORE 8 325 2,600 AMD