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Research: MYOSINS Folding Project #17430

Project #17430 overview

Project Summary AI Beta

This project studies myosin proteins, which power muscle contractions and cell movements. Scientists want to understand how drugs could fix problems with myosin that cause heart diseases like cardiomyopathy and heart failure.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Artur Meller
Institution
Washington University in St. Louis

Work unit

Atoms
171,971
Core
GRO_A7
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 17430

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:58:05

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 17,048 818,304 AMD
2 RYZEN 9 3950X 16-CORE 32 18,191 582,112 AMD
3 RYZEN 9 5950X 16-CORE 32 14,320 458,240 AMD
4 CORE I9-9980XE CPU @ 3.00GHZ 36 11,669 420,084 Intel
5 EPYC 7302P 16-CORE 32 12,274 392,768 AMD
6 RYZEN 9 5900X 12-CORE 24 16,151 387,624 AMD
7 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,615 365,520 AMD
8 RYZEN 9 3900X 12-CORE 24 14,678 352,272 AMD
9 CORE I9-9900K CPU @ 3.60GHZ 16 17,644 282,304 Intel
10 RYZEN 7 5800X 8-CORE 16 15,028 240,448 AMD
11 CORE I9-7920X CPU @ 2.90GHZ 24 9,897 237,528 Intel
12 CORE I9-10900K CPU @ 3.70GHZ 20 11,455 229,100 Intel
13 RYZEN 7 3800X 8-CORE 16 11,821 189,136 AMD
14 XEON CPU E5-2667 V2 @ 3.30GHZ 32 5,708 182,656 Intel
15 RYZEN 7 3700X 8-CORE 16 11,323 181,168 AMD
16 RYZEN THREADRIPPER 1920X 12-CORE 24 7,433 178,392 AMD
17 CORE I9-9900KF CPU @ 3.60GHZ 16 10,555 168,880 Intel
18 RYZEN 5 3600X 6-CORE 12 13,489 161,868 AMD
19 XEON CPU E5-2660 0 @ 2.20GHZ 32 4,216 134,912 Intel
20 RYZEN 5 3600 6-CORE 12 11,110 133,320 AMD
21 RYZEN 7 2700X EIGHT-CORE 16 7,766 124,256 AMD
22 CORE I7-9700K CPU @ 3.60GHZ 8 15,175 121,400 Intel
23 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,692 113,840 Intel
24 RYZEN 7 4800H 16 7,007 112,112 AMD
25 RYZEN 5 2600X SIX-CORE 12 8,714 104,568 AMD
26 CORE I7-9700 CPU @ 3.00GHZ 8 12,746 101,968 Intel
27 RYZEN 5 3500 6-CORE 6 12,992 77,952 AMD
28 XEON CPU E5-2620 V2 @ 2.10GHZ 24 3,244 77,856 Intel
29 RYZEN 7 1700 EIGHT-CORE 16 4,447 71,152 AMD
30 CORE I5-9600K CPU @ 3.70GHZ 6 11,820 70,920 Intel
31 RYZEN 5 1600 SIX-CORE 12 5,582 66,984 AMD
32 CORE I7-3840QM CPU @ 2.80GHZ 8 7,637 61,096 Intel
33 RYZEN 5 2600 SIX-CORE 12 4,762 57,144 AMD
34 CORE I7-8550U CPU @ 1.80GHZ 8 7,068 56,544 Intel
35 CORE I7-8705G CPU @ 3.10GHZ 8 6,801 54,408 Intel
36 CORE I7-6700K CPU @ 4.00GHZ 8 6,692 53,536 Intel
37 XEON W-2123 CPU @ 3.60GHZ 8 6,236 49,888 Intel
38 XEON CPU E5-2690 V3 @ 2.60GHZ 12 3,591 43,092 Intel
39 CORE I7-4790K CPU @ 4.00GHZ 8 5,250 42,000 Intel
40 XEON CPU E5-2650 0 @ 2.00GHZ 16 2,450 39,200 Intel
41 CORE I7-6700 CPU @ 3.40GHZ 8 4,659 37,272 Intel
42 CORE I5-7600 CPU @ 3.50GHZ 4 8,934 35,736 Intel
43 CORE I5-6500 CPU @ 3.20GHZ 4 8,902 35,608 Intel
44 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 4,434 35,472 Intel
45 RYZEN 7 4700U 8 4,305 34,440 AMD
46 CORE I7-3770 CPU @ 3.40GHZ 8 3,567 28,536 Intel
47 CORE I7-4770K CPU @ 3.50GHZ 8 2,602 20,816 Intel
48 CORE I7-6820HQ CPU @ 2.70GHZ 8 2,566 20,528 Intel
49 CORE I5-10210U CPU @ 1.60GHZ 7 2,592 18,144 Intel
50 CORE I3-7100 CPU @ 3.90GHZ 4 4,088 16,352 Intel
51 CORE I5-6260U CPU @ 1.80GHZ 4 3,230 12,920 Intel
52 PHENOM II X4 965 4 2,391 9,564 AMD
53 FX-8320 EIGHT-CORE 8 1,114 8,912 AMD
54 A8-6410 APU 4 172 688 AMD