1. Projects
  2. Research Project Folding Profile

PROJECT #17422 RESEARCH FOR MYOSINS
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001..

PROJECT INFO

Manager(s): Artur Meller

Institution: Washington University in St. Louis

PROJECT WORK UNIT SUMMARY

Atoms: 168,886

Core: GRO_A7

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 31 January 2023 00:15:01

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 31 January 2023 00:15:01

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 EPYC 7302 16-CORE 64 12,475 798,400 AMD
2 RYZEN THREADRIPPER 3960X 24-CORE 48 16,566 795,168 AMD
3 RYZEN 9 3950X 16-CORE 32 19,012 608,384 AMD
4 RYZEN 9 5950X 16-CORE 32 13,963 446,816 AMD
5 CORE I9-10980XE CPU @ 3.00GHZ 36 11,358 408,888 Intel
6 RYZEN 9 5900X 12-CORE 24 16,684 400,416 AMD
7 CORE I9-9980XE CPU @ 3.00GHZ 36 10,388 373,968 Intel
8 RYZEN 9 3900XT 12-CORE 24 14,331 343,944 AMD
9 RYZEN THREADRIPPER 2970WX 24-CORE 48 6,984 335,232 AMD
10 RYZEN 9 3900X 12-CORE 24 13,530 324,720 AMD
11 RYZEN 9 3900 12-CORE 24 12,290 294,960 AMD
12 XEON CPU E5-2667 V4 @ 3.20GHZ 32 9,170 293,440 Intel
13 XEON PLATINUM 8124M CPU @ 3.00GHZ 36 7,915 284,940 Intel
14 CORE I9-9900K CPU @ 3.60GHZ 16 16,292 260,672 Intel
15 RYZEN 7 5800X 8-CORE 16 15,974 255,584 AMD
16 RYZEN THREADRIPPER 2950X 16-CORE 32 7,086 226,752 AMD
17 CORE I9-10900K CPU @ 3.70GHZ 20 10,772 215,440 Intel
18 XEON W-2175 CPU @ 2.50GHZ 28 7,075 198,100 Intel
19 RYZEN THREADRIPPER 1920X 12-CORE 24 7,241 173,784 AMD
20 RYZEN 7 3700X 8-CORE 16 10,794 172,704 AMD
21 CORE I9-7920X CPU @ 2.90GHZ 24 7,154 171,696 Intel
22 XEON CPU E5-2667 V2 @ 3.30GHZ 32 5,354 171,328 Intel
23 XEON W-2245 CPU @ 3.90GHZ 16 10,249 163,984 Intel
24 RYZEN 5 3600X 6-CORE 12 12,849 154,188 AMD
25 EPYC 7571 32-CORE 64 2,399 153,536 AMD
26 CORE I9-10900X CPU @ 3.70GHZ 20 7,275 145,500 Intel
27 RYZEN 7 3800X 8-CORE 16 9,062 144,992 AMD
28 RYZEN 5 5600X 6-CORE 12 12,019 144,228 AMD
29 CORE I9-9900KF CPU @ 3.60GHZ 16 8,969 143,504 Intel
30 CORE I7-9700K CPU @ 3.60GHZ 8 15,731 125,848 Intel
31 CORE I7-5960X CPU @ 3.00GHZ 16 7,797 124,752 Intel
32 RYZEN 5 3600XT 6-CORE 12 10,296 123,552 AMD
33 RYZEN 5 3600 6-CORE 12 10,250 123,000 AMD
34 CORE I7-10700F CPU @ 2.90GHZ 16 7,666 122,656 Intel
35 RYZEN 5 2600X SIX-CORE 12 9,862 118,344 AMD
36 XEON CPU E5-2660 0 @ 2.20GHZ 32 3,500 112,000 Intel
37 RYZEN 7 2700X EIGHT-CORE 16 6,630 106,080 AMD
38 CORE I7-10700K CPU @ 3.80GHZ 16 6,520 104,320 Intel
39 RYZEN 5 PRO 4650G 12 8,620 103,440 AMD
40 CORE I7-8700 CPU @ 3.20GHZ 12 8,577 102,924 Intel
41 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,097 101,940 Intel
42 CORE I7-9700 CPU @ 3.00GHZ 8 12,523 100,184 Intel
43 XEON CPU E5-2680 V3 @ 2.50GHZ 24 4,114 98,736 Intel
44 XEON CPU E5-2670 0 @ 2.60GHZ 32 3,071 98,272 Intel
45 GENUINE CPU 0000 @ 1.60GHZ 32 3,030 96,960 Intel
46 RYZEN 7 4800H 16 6,047 96,752 AMD
47 CORE I7-9700KF CPU @ 3.60GHZ 8 10,642 85,136 Intel
48 CORE2 DUO CPU T7700 @ 2.40GHZ 12 6,982 83,784 Intel
49 CORE I5-10400F CPU @ 2.90GHZ 12 6,879 82,548 Intel
50 RYZEN 3 3100 4-CORE 8 10,176 81,408 AMD
51 XEON CPU E5-2630 0 @ 2.30GHZ 24 3,304 79,296 Intel
52 RYZEN 5 3500 6-CORE 6 12,783 76,698 AMD
53 CORE I7-8700K CPU @ 3.70GHZ 12 6,064 72,768 Intel
54 CORE I5-8400 CPU @ 2.80GHZ 6 12,022 72,132 Intel
55 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,879 69,096 Intel
56 RYZEN 7 1700 EIGHT-CORE 16 4,304 68,864 AMD
57 XEON CPU X5660 @ 2.80GHZ 24 2,787 66,888 Intel
58 RYZEN 5 1600 SIX-CORE 12 5,238 62,856 AMD
59 XEON CPU X5570 @ 2.93GHZ 16 3,876 62,016 Intel
60 CORE I5-9600K CPU @ 3.70GHZ 6 10,142 60,852 Intel
61 CORE I7-3840QM CPU @ 2.80GHZ 8 7,591 60,728 Intel
62 CORE I3-10100 CPU @ 3.60GHZ 8 7,208 57,664 Intel
63 CORE I5-9400F CPU @ 2.90GHZ 6 9,006 54,036 Intel
64 CORE I7-8550U CPU @ 1.80GHZ 8 6,435 51,480 Intel
65 CORE I7-8705G CPU @ 3.10GHZ 8 6,228 49,824 Intel
66 CORE I7-8559U CPU @ 2.70GHZ 8 5,930 47,440 Intel
67 RYZEN 5 2600 SIX-CORE 12 3,932 47,184 AMD
68 CORE I7-6700K CPU @ 4.00GHZ 8 5,753 46,024 Intel
69 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 5,645 45,160 Intel
70 CORE I7-4790K CPU @ 4.00GHZ 8 5,614 44,912 Intel
71 XEON CPU E5-2690 V3 @ 2.60GHZ 12 3,609 43,308 Intel
72 CORE I7-10750H CPU @ 2.60GHZ 12 3,171 38,052 Intel
73 CORE I7-4770 CPU @ 3.40GHZ 8 4,727 37,816 Intel
74 CORE I5-7600 CPU @ 3.50GHZ 4 8,999 35,996 Intel
75 CORE I7-6700 CPU @ 3.40GHZ 8 4,464 35,712 Intel
76 CORE I5-7400 CPU @ 3.00GHZ 4 8,469 33,876 Intel
77 XEON CPU E5-2609 V2 @ 2.50GHZ 8 4,225 33,800 Intel
78 CORE I7-2600K CPU @ 3.40GHZ 8 4,104 32,832 Intel
79 XEON W-10855M CPU @ 2.80GHZ 12 2,721 32,652 Intel
80 CORE I5-4690K CPU @ 3.50GHZ 4 7,961 31,844 Intel
81 CORE I7-9700F CPU @ 3.00GHZ 8 3,947 31,576 Intel
82 CORE I5-6500 CPU @ 3.20GHZ 4 7,640 30,560 Intel
83 CORE I5-8300H CPU @ 2.30GHZ 8 3,662 29,296 Intel
84 XEON E-2124G CPU @ 3.40GHZ 4 6,899 27,596 Intel
85 CORE I5-6600K CPU @ 3.50GHZ 4 6,780 27,120 Intel
86 CORE I7-3770 CPU @ 3.40GHZ 8 3,363 26,904 Intel
87 CORE I7-8565U CPU @ 1.80GHZ 8 3,180 25,440 Intel
88 CORE I7-2600 CPU @ 3.40GHZ 8 3,148 25,184 Intel
89 CORE I7-6700HQ CPU @ 2.60GHZ 8 3,122 24,976 Intel
90 XEON CPU E3-1230 V2 @ 3.30GHZ 8 3,027 24,216 Intel
91 FX-8350 EIGHT-CORE 8 2,945 23,560 AMD
92 PHENOM II X6 1090T 6 3,743 22,458 AMD
93 CORE I7-4770K CPU @ 3.50GHZ 8 2,805 22,440 Intel
94 CORE I5-9300H CPU @ 2.40GHZ 8 2,565 20,520 Intel
95 CORE I5-2500K CPU @ 3.30GHZ 4 4,729 18,916 Intel
96 CORE I3-7100 CPU @ 3.90GHZ 4 3,830 15,320 Intel
97 RYZEN 5 3500U 8 1,797 14,376 AMD
98 CORE I5-4570 CPU @ 3.20GHZ 4 3,193 12,772 Intel
99 CORE I5-2400S CPU @ 2.50GHZ 4 3,045 12,180 Intel
100 CORE I5-6260U CPU @ 1.80GHZ 4 2,857 11,428 Intel
101 CORE I5-5300U CPU @ 2.30GHZ 4 2,698 10,792 Intel
102 FX-8300 EIGHT-CORE 8 1,335 10,680 AMD
103 FX-8320 EIGHT-CORE 8 1,297 10,376 AMD
104 CORE I5-4300U CPU @ 1.90GHZ 4 2,458 9,832 Intel
105 PENTIUM(R) SILVER N5000 CPU @ 1.10GHZ 4 2,415 9,660 Intel
106 CORE I5-7360U CPU @ 2.30GHZ 4 2,336 9,344 Intel
107 PHENOM II X4 965 4 2,278 9,112 AMD
108 CORE I3-6100 CPU @ 3.70GHZ 4 2,109 8,436 Intel
109 CORE I5-3320M CPU @ 2.60GHZ 4 1,962 7,848 Intel
110 CORE I3-6006U CPU @ 2.00GHZ 4 1,872 7,488 Intel
111 CORE2 QUAD CPU Q6600 @ 2.40GHZ 4 1,740 6,960 Intel
112 CORE I5-4460 CPU @ 3.20GHZ 4 1,558 6,232 Intel
113 CORE I5-10210U CPU @ 1.60GHZ 7 736 5,152 Intel
114 A8-6410 APU 4 842 3,368 AMD
115 CELERON(R) CPU G550 @ 2.60GHZ 2 1,402 2,804 Intel
116 ATOM(TM) X5-Z8300 CPU @ 1.44GHZ 4 241 964 Intel
117 GENUINE CPU T1500 @ 1.86GHZ 2 289 578 Intel