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PROJECT #17428 RESEARCH FOR MYOSINS
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001..

PROJECT INFO

Manager(s): Artur Meller

Institution: Washington University in St. Louis

PROJECT WORK UNIT SUMMARY

Atoms: 168,729

Core: GRO_A7

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 27 January 2023 12:14:46

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Friday, 27 January 2023 12:14:46

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 EPYC 7302 16-CORE 64 12,474 798,336 AMD
2 RYZEN THREADRIPPER 3960X 24-CORE 48 15,363 737,424 AMD
3 RYZEN 9 3950X 16-CORE 32 19,460 622,720 AMD
4 RYZEN 9 5950X 16-CORE 32 13,302 425,664 AMD
5 RYZEN 9 5900X 12-CORE 24 17,117 410,808 AMD
6 CORE I9-10980XE CPU @ 3.00GHZ 36 11,046 397,656 Intel
7 CORE I9-9980XE CPU @ 3.00GHZ 36 10,294 370,584 Intel
8 EPYC 7302P 16-CORE 32 11,300 361,600 AMD
9 RYZEN 9 3900XT 12-CORE 24 14,306 343,344 AMD
10 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,130 342,240 AMD
11 RYZEN 9 3900X 12-CORE 24 13,877 333,048 AMD
12 RYZEN 9 3900 12-CORE 24 13,307 319,368 AMD
13 RYZEN 7 5800X 8-CORE 16 17,182 274,912 AMD
14 RYZEN THREADRIPPER 2950X 16-CORE 32 8,472 271,104 AMD
15 CORE I9-9900K CPU @ 3.60GHZ 16 16,542 264,672 Intel
16 CORE I9-10900K CPU @ 3.70GHZ 20 11,583 231,660 Intel
17 CORE I9-7940X CPU @ 3.10GHZ 28 8,138 227,864 Intel
18 CORE I9-7920X CPU @ 2.90GHZ 24 8,265 198,360 Intel
19 CORE I7-10700K CPU @ 3.80GHZ 16 12,390 198,240 Intel
20 RYZEN THREADRIPPER 1920X 12-CORE 24 7,496 179,904 AMD
21 XEON CPU E5-2667 V2 @ 3.30GHZ 32 5,436 173,952 Intel
22 XEON W-2245 CPU @ 3.90GHZ 16 10,534 168,544 Intel
23 RYZEN 7 3700X 8-CORE 16 10,528 168,448 AMD
24 XEON CPU E5-2680 V4 @ 2.40GHZ 28 5,985 167,580 Intel
25 RYZEN 7 3800X 8-CORE 16 9,848 157,568 AMD
26 RYZEN 5 3600X 6-CORE 12 12,918 155,016 AMD
27 CORE I7-8700K CPU @ 3.70GHZ 12 12,559 150,708 Intel
28 RYZEN 5 5600X 6-CORE 12 12,212 146,544 AMD
29 CORE I9-10900X CPU @ 3.70GHZ 20 7,313 146,260 Intel
30 XEON W-2175 CPU @ 2.50GHZ 28 4,728 132,384 Intel
31 RYZEN 5 3600XT 6-CORE 12 10,865 130,380 AMD
32 XEON CPU E5-2680 V3 @ 2.50GHZ 24 5,416 129,984 Intel
33 RYZEN 5 3600 6-CORE 12 10,703 128,436 AMD
34 11TH GEN CORE I9-11900K @ 3.50GHZ 16 7,973 127,568 Intel
35 CORE I7-10700F CPU @ 2.90GHZ 16 7,924 126,784 Intel
36 RYZEN 7 2700X EIGHT-CORE 16 7,919 126,704 AMD
37 EPYC 7571 32-CORE 64 1,911 122,304 AMD
38 CORE I7-9700K CPU @ 3.60GHZ 8 15,260 122,080 Intel
39 XEON CPU E5-2660 0 @ 2.20GHZ 32 3,776 120,832 Intel
40 RYZEN 5 1600X SIX-CORE 12 9,469 113,628 AMD
41 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,554 111,080 Intel
42 CORE I7-9700 CPU @ 3.00GHZ 8 12,552 100,416 Intel
43 RYZEN 7 4800H 16 6,242 99,872 AMD
44 RYZEN 5 PRO 4650G 12 8,278 99,336 AMD
45 RYZEN 5 2600X SIX-CORE 12 7,760 93,120 AMD
46 CORE2 DUO CPU T7700 @ 2.40GHZ 12 6,822 81,864 Intel
47 CORE I5-10400F CPU @ 2.90GHZ 12 6,790 81,480 Intel
48 RYZEN 7 1800X EIGHT-CORE 16 5,021 80,336 AMD
49 RYZEN 7 PRO 4750G 16 5,020 80,320 AMD
50 RYZEN 5 3500 6-CORE 6 13,330 79,980 AMD
51 XEON CPU E5-2630 0 @ 2.30GHZ 24 3,306 79,344 Intel
52 RYZEN 3 3100 4-CORE 8 9,349 74,792 AMD
53 CORE I5-9600KF CPU @ 3.70GHZ 6 12,297 73,782 Intel
54 XEON CPU E5-2620 V2 @ 2.10GHZ 24 3,004 72,096 Intel
55 RYZEN 7 1700 EIGHT-CORE 16 4,370 69,920 AMD
56 CORE I7-10710U CPU @ 1.10GHZ 12 5,814 69,768 Intel
57 CORE I7-3840QM CPU @ 2.80GHZ 8 8,210 65,680 Intel
58 RYZEN 5 1600 SIX-CORE 12 5,405 64,860 AMD
59 RYZEN 5 3500X 6-CORE 6 10,801 64,806 AMD
60 RYZEN 5 2600 SIX-CORE 12 5,114 61,368 AMD
61 CORE I5-8400 CPU @ 2.80GHZ 6 10,214 61,284 Intel
62 CORE I7-4910MQ CPU @ 2.90GHZ 8 7,580 60,640 Intel
63 CORE I7-5960X CPU @ 3.00GHZ 16 3,680 58,880 Intel
64 CORE I5-9400F CPU @ 2.90GHZ 6 9,381 56,286 Intel
65 CORE I3-6100 CPU @ 3.70GHZ 4 13,474 53,896 Intel
66 CORE I7-8550U CPU @ 1.80GHZ 8 6,677 53,416 Intel
67 RYZEN 5 4600HS 12 4,357 52,284 AMD
68 CORE I7-8700 CPU @ 3.20GHZ 12 4,018 48,216 Intel
69 CORE I7-6800K CPU @ 3.40GHZ 12 3,973 47,676 Intel
70 CORE I7-8705G CPU @ 3.10GHZ 8 5,860 46,880 Intel
71 CORE I7-4790K CPU @ 4.00GHZ 8 5,419 43,352 Intel
72 XEON W-10855M CPU @ 2.80GHZ 12 3,580 42,960 Intel
73 CORE I7-6700K CPU @ 4.00GHZ 8 5,253 42,024 Intel
74 XEON CPU E5-2690 V3 @ 2.60GHZ 12 3,401 40,812 Intel
75 CORE I7-9700F CPU @ 3.00GHZ 8 4,881 39,048 Intel
76 CORE I7-4770 CPU @ 3.40GHZ 8 4,778 38,224 Intel
77 CORE I7-6700T CPU @ 2.80GHZ 8 4,644 37,152 Intel
78 CORE I5-7600 CPU @ 3.50GHZ 4 9,105 36,420 Intel
79 XEON CPU E5-2609 V2 @ 2.50GHZ 8 4,528 36,224 Intel
80 CORE I7-6700 CPU @ 3.40GHZ 8 4,081 32,648 Intel
81 CORE I5-4670K CPU @ 3.40GHZ 4 7,420 29,680 Intel
82 CORE I7-9750H CPU @ 2.60GHZ 12 2,442 29,304 Intel
83 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 3,639 29,112 Intel
84 RYZEN 7 4700U 8 3,605 28,840 AMD
85 CORE I5-6500 CPU @ 3.20GHZ 4 7,188 28,752 Intel
86 CORE I7-4850HQ CPU @ 2.30GHZ 8 3,409 27,272 Intel
87 CORE I7-3770 CPU @ 3.40GHZ 8 3,367 26,936 Intel
88 CORE I5-4690K CPU @ 3.50GHZ 4 6,509 26,036 Intel
89 CORE I5-6600K CPU @ 3.50GHZ 4 6,498 25,992 Intel
90 CORE I7-8565U CPU @ 1.80GHZ 8 3,244 25,952 Intel
91 CORE I3-8100T CPU @ 3.10GHZ 4 6,436 25,744 Intel
92 CORE I7-2600K CPU @ 3.40GHZ 8 3,200 25,600 Intel
93 CORE I7-2600 CPU @ 3.40GHZ 8 3,084 24,672 Intel
94 XEON CPU E3-1230 V2 @ 3.30GHZ 8 3,066 24,528 Intel
95 CORE I5-4570 CPU @ 3.20GHZ 4 5,951 23,804 Intel
96 RYZEN 5 1400 QUAD-CORE 8 2,950 23,600 AMD
97 CORE I5-8250U CPU @ 1.60GHZ 8 2,941 23,528 Intel
98 PHENOM II X6 1090T 6 3,908 23,448 AMD
99 CORE I7-6700HQ CPU @ 2.60GHZ 8 2,897 23,176 Intel
100 CORE I5-2500K CPU @ 3.30GHZ 4 4,873 19,492 Intel
101 CORE I3-8100 CPU @ 3.60GHZ 4 4,562 18,248 Intel
102 CORE I7-3632QM CPU @ 2.20GHZ 8 2,228 17,824 Intel
103 CORE I7-4770K CPU @ 3.50GHZ 8 2,140 17,120 Intel
104 RYZEN 5 3500U 8 2,091 16,728 AMD
105 CORE I3-7100 CPU @ 3.90GHZ 4 4,012 16,048 Intel
106 CORE I5-2400S CPU @ 2.50GHZ 4 3,899 15,596 Intel
107 CORE I3-2120 CPU @ 3.30GHZ 4 3,747 14,988 Intel
108 CORE I5-7300HQ CPU @ 2.50GHZ 4 3,725 14,900 Intel
109 CORE I5-6260U CPU @ 1.80GHZ 4 3,132 12,528 Intel
110 FX-8300 EIGHT-CORE 8 1,276 10,208 AMD
111 CORE I7-5930K CPU @ 3.50GHZ 12 842 10,104 Intel
112 PHENOM II X4 965 4 2,520 10,080 AMD
113 FX-8320 EIGHT-CORE 8 1,257 10,056 AMD
114 PENTIUM(R) SILVER N5000 CPU @ 1.10GHZ 4 2,442 9,768 Intel
115 PENTIUM(R) CPU G4560 @ 3.50GHZ 4 1,993 7,972 Intel
116 A10-6700 APU RADEON(TM) HD GRAPHICS 4 1,976 7,904 AMD
117 FX-6300 SIX-CORE 6 1,236 7,416 AMD
118 CORE I3-6006U CPU @ 2.00GHZ 4 1,797 7,188 Intel
119 CORE I5-4200U CPU @ 1.60GHZ 4 1,678 6,712 Intel
120 CORE I5-4300U CPU @ 1.90GHZ 4 1,454 5,816 Intel
121 CELERON(R) CPU G550 @ 2.60GHZ 2 1,851 3,702 Intel
122 CORE2 DUO CPU E6750 @ 2.66GHZ 2 1,235 2,470 Intel
123 A8-6410 APU 4 373 1,492 AMD