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Research: MYOSINS Folding Project #17436

Project #17436 overview

Project Summary AI Beta

This project studies myosin proteins which are essential for movement in the body, from muscle contraction to moving things inside cells. Scientists want to understand how drugs can fix problems with myosin that cause heart diseases like cardiomyopathy and heart failure. Myosin is so important it was even featured as Molecule of the Month!
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Artur Meller
Institution
Washington University in St. Louis

Work unit

Atoms
167,878
Core
GRO_A7
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 17436

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:57:59

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 5950X 16-CORE 32 19,150 612,800 AMD
2 RYZEN THREADRIPPER 3960X 24-CORE 48 9,588 460,224 AMD
3 RYZEN 9 3900 12-CORE 24 15,973 383,352 AMD
4 RYZEN 7 5800X 8-CORE 16 17,036 272,576 AMD
5 RYZEN 7 3700X 8-CORE 16 14,659 234,544 AMD
6 11TH GEN CORE I9-11900K @ 3.50GHZ 16 9,735 155,760 Intel
7 RYZEN 7 3800X 8-CORE 16 7,723 123,568 AMD
8 RYZEN 5 3600 6-CORE 12 9,642 115,704 AMD
9 RYZEN 5 2600X SIX-CORE 12 8,719 104,628 AMD
10 RYZEN 5 2600 SIX-CORE 12 5,543 66,516 AMD
11 11TH GEN CORE I5-11400 @ 2.60GHZ 12 3,964 47,568 Intel
12 XEON W-10855M CPU @ 2.80GHZ 12 3,642 43,704 Intel
13 CORE I5-7600 CPU @ 3.50GHZ 4 8,757 35,028 Intel
14 CORE I5-8300H CPU @ 2.30GHZ 8 4,332 34,656 Intel
15 CORE I5-4690K CPU @ 3.50GHZ 4 7,201 28,804 Intel
16 CORE I5-3330 CPU @ 3.00GHZ 4 5,329 21,316 Intel
17 CORE I5-7200U CPU @ 2.50GHZ 4 2,393 9,572 Intel
18 CORE M3-7Y30 CPU @ 1.00GHZ 4 2,227 8,908 Intel
19 CORE I3-6100U CPU @ 2.30GHZ 4 2,109 8,436 Intel