PROJECT #17225 RESEARCH FOR G-PROTEINS
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
G-proteins play central role in various signalling pathways involved in vision, taste, oflaction, muscle contraction and neurotransmission.
G-proteins regulate these signalling pathways by switching between 'active' and 'inactive' states, dictated by the type nucleotide bound to their active site.
When bound to gaunosine dinucleotide (GDP), G-proteins adopt inactive state.
Dissociation of GDP and subsequent binding of gaunosine trinucleotide (GTP) activates G-proteins, which in turn activate downstream signalling pathways.
GDP dissociation is the rate limiting step in activation of G-proteins and misregulation of this process can often lead to disease conditions.
in this project, we are studying the mechanism of GDP dissociation process..
PROJECT INFO
Manager(s): Neha Vithani
Institution: Washington University in St. Louis
PROJECT WORK UNIT SUMMARY
Atoms: 116,317
Core: GRO_A7
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Tuesday, 07 February 2023 12:14:58
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
---|
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Tuesday, 07 February 2023 12:14:58
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
---|---|---|---|---|---|
1 | EPYC 7302 16-CORE | 64 | 13,622 | 871,808 | AMD |
2 | RYZEN 9 3950X 16-CORE | 32 | 24,435 | 781,920 | AMD |
3 | RYZEN 9 5950X 16-CORE | 32 | 11,824 | 378,368 | AMD |
4 | RYZEN 7 5800X 8-CORE | 16 | 18,549 | 296,784 | AMD |
5 | RYZEN 5 3600 6-CORE | 12 | 12,753 | 153,036 | AMD |
6 | CORE I7-10700 CPU @ 2.90GHZ | 16 | 6,992 | 111,872 | Intel |
7 | CORE I3-9100F CPU @ 3.60GHZ | 4 | 13,062 | 52,248 | Intel |
8 | CORE I7-6700K CPU @ 4.00GHZ | 8 | 6,176 | 49,408 | Intel |
9 | XEON CPU E7- 8870 @ 2.40GHZ | 40 | 724 | 28,960 | Intel |
10 | CORE I5-4460 CPU @ 3.20GHZ | 4 | 1,400 | 5,600 | Intel |