PROJECT #17222 RESEARCH FOR G-PROTEINS
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

G-proteins play central role in various signalling pathways involved in vision, taste, oflaction, muscle contraction and neurotransmission. G-proteins regulate these signalling pathways by switching between 'active' and 'inactive' states, dictated by the type nucleotide bound to their active site. When bound to gaunosine dinucleotide (GDP), G-proteins adopt inactive state. Dissociation of GDP and subsequent binding of gaunosine trinucleotide (GTP) activates G-proteins, which in turn activate downstream signalling pathways. GDP dissociation is the rate limiting step in activation of G-proteins and misregulation of this process can often lead to disease conditions. in this project, we are studying the mechanism of GDP dissociation process.

PROJECT INFO

Manager(s): Neha Vithani

Institution: Washington University in St. Louis

PROJECT WORK UNIT SUMMARY

Atoms: 142,277

Core: GRO_A7

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 28 July 2021 15:34:03

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 28 July 2021 15:34:03

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 26,733 855,456 AMD
2 EPYC 7302 16-CORE 64 13,299 851,136 AMD
3 RYZEN 9 5950X 16-CORE 32 17,821 570,272 AMD
4 RYZEN 9 3900X 12-CORE 24 14,696 352,704 AMD
5 RYZEN THREADRIPPER 2970WX 24-CORE 48 6,647 319,056 AMD
6 RYZEN 7 3700X 8-CORE 16 11,696 187,136 AMD
7 XEON CPU E5-2667 V2 @ 3.30GHZ 32 5,841 186,912 Intel
8 RYZEN 7 3800X 8-CORE 16 11,276 180,416 AMD
9 CORE I9-10900X CPU @ 3.70GHZ 20 8,623 172,460 Intel
10 CORE I7-9700K CPU @ 3.60GHZ 8 18,921 151,368 Intel
11 RYZEN 5 3600 6-CORE 12 11,620 139,440 AMD
12 RYZEN 5 2600X SIX-CORE 12 8,825 105,900 AMD
13 CORE I5-10400F CPU @ 2.90GHZ 12 7,930 95,160 Intel
14 RYZEN 7 2700X EIGHT-CORE 16 5,596 89,536 AMD
15 XEON CPU E5-2620 V2 @ 2.10GHZ 24 3,031 72,744 Intel
16 CORE I3-9100F CPU @ 3.60GHZ 4 12,571 50,284 Intel
17 CORE I7-4790K CPU @ 4.00GHZ 8 5,916 47,328 Intel
18 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 5,905 47,240 Intel
19 CORE I5-7600 CPU @ 3.50GHZ 4 9,722 38,888 Intel
20 CORE I5-7400 CPU @ 3.00GHZ 4 4,872 19,488 Intel
21 CORE I5-7360U CPU @ 2.30GHZ 4 2,834 11,336 Intel
22 PENTIUM(R) SILVER N5000 CPU @ 1.10GHZ 4 2,676 10,704 Intel
23 FX-8320 EIGHT-CORE 8 732 5,856 AMD