Folding project #14958, CANCER research

Research section Research projects and references

Project #14958 overview

Project Summary AI Beta

This project looks at Class F Receptors and Patched proteins which help control how cells grow. When these proteins go wrong, they can cause cancers like Basal Cell Carcinoma and Medulloblastoma. By using computer simulations, we hope to learn how these proteins work so we can better understand these diseases.

Automated summary; simplified and may not be fully accurate.

Project team

Manager(s): Prateek Bansal
Institution: University of Illinois Urbana-Champaign

Work unit

Atoms: 104,869
Core: 0x22
Status: Public

Source material

Official Project Description

Class F Receptors and Patched Membrane Protein Class F Receptors and Patched are human proteins that are involved in the control of cell differentiation.

Over-activation/inactivation of these proteins has links to Basal Cell Carcinoma and Medulloblastoma.

Through simulations we aim to understand the activation mechanisms of these proteins, giving us a way to probe into the pathogenesis of the disease.

Reading reference

Related Terms Glossary AI Beta

Automated high-level definitions; simplified and may not be fully accurate.

Class F Receptors

A family of cell surface receptors involved in signal transduction.

Technical: MedicineBiotechnology / Cellular Biology

Class F Receptors are a group of proteins found on the surface of cells. They act like antennas, receiving signals from other molecules and triggering changes inside the cell. These signals are important for controlling how cells grow and develop.

Patched

A transmembrane protein that regulates cell growth and differentiation.

Technical: MedicineBiotechnology / Cellular Biology

Patched is a protein embedded in the membrane of cells. It plays a crucial role in controlling how cells grow and divide. When Patched binds to certain molecules, it can either promote or inhibit cell proliferation.

Basal Cell Carcinoma

A type of skin cancer that originates in the basal cells.

Clinical: HealthcareMedicine / Oncology

Basal Cell Carcinoma is a common form of skin cancer. It starts in the basal cells, which are located in the deepest layer of the epidermis (the outermost layer of skin). This type of cancer often appears as a pearly or waxy bump on the skin.

Medulloblastoma

A type of brain tumor that originates in the cerebellum.

Clinical: HealthcareMedicine / Neurology

Medulloblastoma is a malignant brain tumor that develops in the cerebellum, the part of the brain responsible for coordination and balance. It is most common in children.

GPU PPD Averages

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 5090 GB202 [GeForce RTX 5090]	Nvidia	GB202	23,686,755	50,000	473.74	0 ^hrs 3 ^mins
2	GeForce RTX 4090 AD102 [GeForce RTX 4090]	Nvidia	AD102	17,192,672	250,967	68.51	0 ^hrs 21 ^mins
3	GeForce RTX 4080 AD103 [GeForce RTX 4080]	Nvidia	AD103	12,804,884	212,892	60.15	0 ^hrs 24 ^mins
4	GeForce RTX 4080 SUPER AD103 [GeForce RTX 4080 SUPER]	Nvidia	AD103	12,578,861	123,741	101.65	0 ^hrs 14 ^mins
5	GeForce RTX 5080 GB203 [GeForce RTX 5080]	Nvidia	GB203	12,559,866	50,000	251.20	0 ^hrs 6 ^mins
6	GeForce RTX 5070 Ti GB203 [GeForce RTX 5070 Ti]	Nvidia	GB203	10,732,420	100,283	107.02	0 ^hrs 13 ^mins
7	GeForce RTX 4070 Ti AD104 [GeForce RTX 4070 Ti]	Nvidia	AD104	9,384,577	324,922	28.88	0 ^hrs 50 ^mins
8	GeForce RTX 4070 SUPER AD104 [GeForce RTX 4070 SUPER]	Nvidia	AD104	8,996,044	236,717	38.00	0 ^hrs 38 ^mins
9	GeForce RTX 5070 GB205 [GeForce RTX 5070]	Nvidia	GB205	8,661,600	50,000	173.23	0 ^hrs 8 ^mins
10	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	8,160,763	304,301	26.82	0 ^hrs 54 ^mins
11	GeForce RTX 4070 Ti SUPER AD103 [GeForce RTX 4070 Ti SUPER]	Nvidia	AD103	7,984,905	128,037	62.36	0 ^hrs 23 ^mins
12	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	7,665,987	158,901	48.24	0 ^hrs 30 ^mins
13	GeForce RTX 4070 AD104 [GeForce RTX 4070]	Nvidia	AD104	7,477,641	103,351	72.35	0 ^hrs 20 ^mins
14	RTX 5000 Ada Generation Laptop GPU AD103GLM [RTX 5000 Ada Generation Laptop GPU]	Nvidia	AD103GLM	6,928,014	293,440	23.61	1 ^hrs 1 ^mins
15	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	6,773,636	248,938	27.21	0 ^hrs 53 ^mins
16	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	5,908,760	253,867	23.28	1 ^hrs 2 ^mins
17	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	5,891,615	79,794	73.84	0 ^hrs 20 ^mins
18	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	5,688,043	102,178	55.67	0 ^hrs 26 ^mins
19	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	4,890,847	262,519	18.63	1 ^hrs 17 ^mins

20	GeForce RTX 4060 Ti AD106 [GeForce RTX 4060 Ti]	Nvidia	AD106	4,888,305	260,333	18.78	1 ^hrs 17 ^mins
21	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	4,823,779	260,249	18.54	1 ^hrs 18 ^mins
22	TITAN V GV100 [TITAN V] M 12288	Nvidia	GV100	4,523,779	63,953	70.74	0 ^hrs 20 ^mins
23	Radeon RX 7900XT/XTX/GRE Navi 31 [Radeon RX 7900XT/XTX/GRE]	AMD	Navi 31	4,195,788	140,403	29.88	0 ^hrs 48 ^mins
24	Radeon RX 7900XT/XTX Navi 31 [Radeon RX 7900XT/XTX]	AMD	Navi 31	4,071,903	245,724	16.57	1 ^hrs 27 ^mins
25	Radeon RX 9070(XT) Navi 48 [Radeon RX 9070(XT)]	AMD	Navi 48	3,966,670	84,251	47.08	0 ^hrs 31 ^mins
26	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,817,691	239,789	15.92	1 ^hrs 30 ^mins
27	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	3,733,079	210,818	17.71	1 ^hrs 21 ^mins
28	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	3,499,449	79,985	43.75	0 ^hrs 33 ^mins
29	GeForce RTX 4070 Max-Q / Mobile AD106M [GeForce RTX 4070 Max-Q / Mobile]	Nvidia	AD106M	3,463,791	50,000	69.28	0 ^hrs 21 ^mins
30	Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT]	AMD	Navi 21	3,083,236	225,276	13.69	1 ^hrs 45 ^mins
31	GeForce RTX 4060 AD107 [GeForce RTX 4060]	Nvidia	AD107	3,058,414	123,830	24.70	0 ^hrs 58 ^mins
32	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A]	Nvidia	TU106	2,960,179	50,000	59.20	0 ^hrs 24 ^mins
33	Radeon RX 6950 XT Navi 21 [Radeon RX 6950 XT]	AMD	Navi 21	2,897,017	164,017	17.66	1 ^hrs 22 ^mins
34	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	2,659,265	213,695	12.44	1 ^hrs 56 ^mins
35	Radeon RX 6800(XT)/6900XT Navi 21 [Radeon RX 6800(XT)/6900XT]	AMD	Navi 21	2,646,861	214,669	12.33	1 ^hrs 57 ^mins
36	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,564,513	190,590	13.46	1 ^hrs 47 ^mins
37	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,530,406	192,459	13.15	1 ^hrs 50 ^mins
38	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,321,674	204,673	11.34	2 ^hrs 7 ^mins
39	GeForce RTX 2060 12GB TU106 [GeForce RTX 2060 12GB]	Nvidia	TU106	2,178,445	184,813	11.79	2 ^hrs 2 ^mins

40	Radeon RX 6800/6800XT/6900XT Navi 21 [Radeon RX 6800/6800XT/6900XT]	AMD	Navi 21	2,165,265	199,080	10.88	2 ^hrs 12 ^mins
41	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,035,740	160,004	12.72	1 ^hrs 53 ^mins
42	GeForce RTX 2070 Mobile / Max-Q Refresh TU106M [GeForce RTX 2070 Mobile / Max-Q Refresh]	Nvidia	TU106M	2,021,076	195,434	10.34	2 ^hrs 19 ^mins
43	GeForce RTX 4060 Max-Q / Mobile AD107M [GeForce RTX 4060 Max-Q / Mobile]	Nvidia	AD107M	1,997,581	194,290	10.28	2 ^hrs 20 ^mins
44	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,887,298	120,605	15.65	1 ^hrs 32 ^mins
45	GeForce RTX 3050 8GB GA107 [GeForce RTX 3050 8GB]	Nvidia	GA107	1,579,038	175,530	9.00	2 ^hrs 40 ^mins
46	GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q]	Nvidia	GA106M	1,564,570	173,053	9.04	2 ^hrs 39 ^mins
47	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,506,118	94,154	16.00	1 ^hrs 30 ^mins
48	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,436,992	177,486	8.10	2 ^hrs 58 ^mins
49	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,408,865	173,086	8.14	2 ^hrs 57 ^mins
50	GeForce GTX 1660 Mobile TU116M [GeForce GTX 1660 Mobile]	Nvidia	TU116M	1,322,439	171,951	7.69	3 ^hrs 7 ^mins
51	RTX A2000 12GB GA106 [RTX A2000 12GB]	Nvidia	GA106	1,295,002	50,000	25.90	0 ^hrs 56 ^mins
52	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	1,292,179	50,000	25.84	0 ^hrs 56 ^mins
53	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,244,749	98,888	12.59	1 ^hrs 54 ^mins
54	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	1,222,601	165,851	7.37	3 ^hrs 15 ^mins
55	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,157,571	159,056	7.28	3 ^hrs 18 ^mins
56	P104-100 GP104 [P104-100]	Nvidia	GP104	1,105,055	92,365	11.96	2 ^hrs 0 ^mins
57	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	1,096,219	159,586	6.87	3 ^hrs 30 ^mins
58	Radeon RX 6650XT Navi 23 [Radeon RX 6650XT]	AMD	Navi 23	1,077,521	156,852	6.87	3 ^hrs 30 ^mins
59	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	988,504	131,332	7.53	3 ^hrs 11 ^mins

60	RTX A1000 GA107GL [RTX A1000]	Nvidia	GA107GL	967,905	50,000	19.36	1 ^hrs 14 ^mins
61	Radeon RX 6700(XT)/6800M Navi 22 XT-XL [Radeon RX 6700(XT)/6800M]	AMD	Navi 22 XT-XL	929,708	93,330	9.96	2 ^hrs 25 ^mins
62	Radeon RX 6600(XT/M) Navi 23 XT-XL [Radeon RX 6600(XT/M)]	AMD	Navi 23 XT-XL	901,350	148,088	6.09	3 ^hrs 57 ^mins
63	Radeon RX 6700/6700XT/6800M Navi 22 XT-XL [Radeon RX 6700/6700XT/6800M]	AMD	Navi 22 XT-XL	846,214	138,231	6.12	3 ^hrs 55 ^mins
64	Radeon RX 6600/6600 XT/6600M Navi 23 XT-XL [Radeon RX 6600/6600 XT/6600M]	AMD	Navi 23 XT-XL	816,273	145,380	5.61	4 ^hrs 16 ^mins
65	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	766,154	56,514	13.56	1 ^hrs 46 ^mins
66	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	705,419	72,368	9.75	2 ^hrs 28 ^mins
67	Tesla P4 GP104GL [Tesla P4] 5704	Nvidia	GP104GL	699,174	137,687	5.08	4 ^hrs 44 ^mins
68	P106-100 GP106 [P106-100]	Nvidia	GP106	690,897	98,494	7.01	3 ^hrs 25 ^mins
69	Quadro T1200 Mobile TU117GLM [Quadro T1200 Mobile]	Nvidia	TU117GLM	665,658	139,191	4.78	5 ^hrs 1 ^mins
70	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	625,616	132,318	4.73	5 ^hrs 5 ^mins
71	GeForce GTX 1650 TU116 [GeForce GTX 1650] 3091	Nvidia	TU116	601,357	132,654	4.53	5 ^hrs 18 ^mins
72	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	569,837	135,315	4.21	5 ^hrs 42 ^mins
73	Quadro T1000 Mobile TU117GLM [Quadro T1000 Mobile]	Nvidia	TU117GLM	534,409	50,000	10.69	2 ^hrs 15 ^mins
74	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	479,759	50,000	9.60	2 ^hrs 30 ^mins
75	GeForce GTX Titan X GM200 [GeForce GTX Titan X] 6144	Nvidia	GM200	466,722	50,000	9.33	2 ^hrs 34 ^mins
76	RX 470/480/570/580/590 Ellesmere XT [RX 470/480/570/580/590]	AMD	Ellesmere XT	391,168	72,677	5.38	4 ^hrs 28 ^mins
77	GeForce GTX 1050 Ti GP107 [GeForce GTX 1050 Ti] 2138	Nvidia	GP107	390,387	56,338	6.93	3 ^hrs 28 ^mins
78	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	363,152	50,000	7.26	3 ^hrs 18 ^mins
79	GeForce GTX 960 GM206 [GeForce GTX 960] 2308	Nvidia	GM206	307,328	62,818	4.89	4 ^hrs 54 ^mins

80	GeForce GTX 1650 TU106 [GeForce GTX 1650]	Nvidia	TU106	264,186	50,000	5.28	4 ^hrs 33 ^mins
81	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	245,682	97,105	2.53	9 ^hrs 29 ^mins
82	Quadro P1000 GP107GL [Quadro P1000]	Nvidia	GP107GL	225,902	55,493	4.07	5 ^hrs 54 ^mins
83	GeForce GTX 770 GK104 [GeForce GTX 770] 3213	Nvidia	GK104	148,481	50,000	2.97	8 ^hrs 5 ^mins
84	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	147,845	54,233	2.73	8 ^hrs 48 ^mins
85	RX Vega M GL Polaris 22 XL [RX Vega M GL]	AMD	Polaris 22 XL	147,658	50,000	2.95	8 ^hrs 8 ^mins
86	Quadro P620 GP107GL [Quadro P620]	Nvidia	GP107GL	133,099	79,167	1.68	14 ^hrs 17 ^mins
87	GeForce GTX 1050 LP GP107 [GeForce GTX 1050 LP] 1862	Nvidia	GP107	124,320	86,544	1.44	16 ^hrs 42 ^mins
88	GeForce GTX 670/GTX 760Ti OEM GK104 [GeForce GTX 670/GTX 760Ti OEM] 2634	Nvidia	GK104	119,243	50,000	2.38	10 ^hrs 4 ^mins
89	Quadro K1200 GM107GL [Quadro K1200]	Nvidia	GM107GL	102,704	57,045	1.80	13 ^hrs 20 ^mins
90	GeForce GT 1030 GP108 [GeForce GT 1030]	Nvidia	GP108	74,856	50,000	1.50	16 ^hrs 2 ^mins

Research: CANCER Folding Project #14958

Project Summary AI Beta

Project team

Work unit

Official Project Description

Hardware Performance for Project 14958

GPU PPD Averages

Research: CANCER Folding Project #14958

Project Summary AI Beta

Project team

Work unit

Related projects

GPU PPD Averages