Folding project #14949, CANCER research

Research section Research projects and references

Project #14949 overview

Project Summary AI Beta

This project looks at Class F Receptors and Patched proteins, which help control how cells grow and change. When these proteins don't work right, it can lead to cancers like Basal Cell Carcinoma and Medulloblastoma. By using computer simulations, we hope to learn how these proteins work so we can better understand and treat these diseases.

Automated summary; simplified and may not be fully accurate.

Project team

Manager(s): Prateek Bansal
Institution: University of Illinois Urbana-Champaign

Work unit

Atoms: 104,624
Core: 0x22
Status: Public

Source material

Official Project Description

Class F Receptors and Patched Membrane Protein Class F Receptors and Patched are human proteins that are involved in the control of cell differentiation.

Over-activation/inactivation of these proteins has links to Basal Cell Carcinoma and Medulloblastoma.

Through simulations we aim to understand the activation mechanisms of these proteins, giving us a way to probe into the pathogenesis of the disease.

Reading reference

Related Terms Glossary AI Beta

Automated high-level definitions; simplified and may not be fully accurate.

Class F Receptors

Membrane receptors that regulate cell differentiation.

Scientific: PharmaceuticalBiotechnology / Protein Research

Class F Receptors are a type of protein found on the surface of cells. They play a crucial role in controlling how cells develop and specialize. When these receptors are overactive or inactive, it can lead to problems like Basal Cell Carcinoma and Medulloblastoma, which are types of cancer.

Patched Membrane Protein

A protein involved in signal transduction pathways.

Scientific: PharmaceuticalBiotechnology / Protein Research

Patched Membrane Protein is another type of protein found on the surface of cells. It acts as a part of signaling pathways that tell cells what to do. Dysfunction of this protein can also contribute to certain cancers.

Basal Cell Carcinoma

A type of skin cancer that originates in the basal cells.

Pathology: HealthcareMedicine / Oncology

Basal Cell Carcinoma is the most common type of skin cancer. It starts in the bottom layer of the epidermis (the outer layer of skin) and often appears as a pearly or waxy bump.

Medulloblastoma

A type of brain cancer that arises from the cerebellum.

Pathology: HealthcareMedicine / Neuro-oncology

Medulloblastoma is a type of aggressive brain tumor that develops in the cerebellum, the part of the brain responsible for balance and coordination.

GPU PPD Averages

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 4090 AD102 [GeForce RTX 4090]	Nvidia	AD102	15,403,430	183,136	84.11	0 ^hrs 17 ^mins
2	GeForce RTX 4080 AD103 [GeForce RTX 4080]	Nvidia	AD103	12,289,115	170,244	72.19	0 ^hrs 20 ^mins
3	GeForce RTX 4070 Ti AD104 [GeForce RTX 4070 Ti]	Nvidia	AD104	10,622,554	168,164	63.17	0 ^hrs 23 ^mins
4	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	7,820,165	147,821	52.90	0 ^hrs 27 ^mins
5	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	7,134,987	144,494	49.38	0 ^hrs 29 ^mins
6	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	6,931,545	145,649	47.59	0 ^hrs 30 ^mins
7	GeForce RTX 3080 12GB GA102 [GeForce RTX 3080 12GB]	Nvidia	GA102	6,539,097	137,646	47.51	0 ^hrs 30 ^mins
8	GeForce RTX 4070 AD104 [GeForce RTX 4070]	Nvidia	AD104	6,253,366	137,250	45.56	0 ^hrs 32 ^mins
9	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	6,092,251	135,604	44.93	0 ^hrs 32 ^mins
10	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	6,050,094	134,832	44.87	0 ^hrs 32 ^mins
11	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	5,128,095	128,993	39.75	0 ^hrs 36 ^mins
12	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	4,670,683	125,225	37.30	0 ^hrs 39 ^mins
13	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,179,382	121,663	34.35	0 ^hrs 42 ^mins
14	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,813,555	116,261	32.80	0 ^hrs 44 ^mins
15	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	3,740,974	116,595	32.09	0 ^hrs 45 ^mins
16	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	3,218,523	110,205	29.20	0 ^hrs 49 ^mins
17	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	3,129,885	109,594	28.56	0 ^hrs 50 ^mins
18	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A]	Nvidia	TU106	3,100,241	109,175	28.40	0 ^hrs 51 ^mins
19	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	3,079,436	108,863	28.29	0 ^hrs 51 ^mins

20	Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT]	AMD	Navi 21	3,009,723	108,262	27.80	0 ^hrs 52 ^mins
21	Radeon RX 7900XT/XTX Navi 31 [Radeon RX 7900XT/XTX]	AMD	Navi 31	2,865,983	104,999	27.30	0 ^hrs 53 ^mins
22	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	2,818,290	104,373	27.00	0 ^hrs 53 ^mins
23	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,814,341	105,483	26.68	0 ^hrs 54 ^mins
24	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,377,256	100,502	23.65	1 ^hrs 1 ^mins
25	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	2,351,187	99,652	23.59	1 ^hrs 1 ^mins
26	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	2,301,325	99,413	23.15	1 ^hrs 2 ^mins
27	Radeon RX 6800/6800XT/6900XT Navi 21 [Radeon RX 6800/6800XT/6900XT]	AMD	Navi 21	2,227,512	97,394	22.87	1 ^hrs 3 ^mins
28	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,222,050	96,722	22.97	1 ^hrs 3 ^mins
29	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,045,659	88,829	23.03	1 ^hrs 3 ^mins
30	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,799,397	91,174	19.74	1 ^hrs 13 ^mins
31	Geforce RTX 3050 GA106 [Geforce RTX 3050]	Nvidia	GA106	1,575,682	87,788	17.95	1 ^hrs 20 ^mins
32	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	1,425,490	84,168	16.94	1 ^hrs 25 ^mins
33	RTX A2000 GA106 [RTX A2000]	Nvidia	GA106	1,364,779	83,055	16.43	1 ^hrs 28 ^mins
34	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,257,543	79,718	15.77	1 ^hrs 31 ^mins
35	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,196,422	78,267	15.29	1 ^hrs 34 ^mins
36	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,170,391	79,531	14.72	1 ^hrs 38 ^mins
37	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	1,089,434	77,455	14.07	1 ^hrs 42 ^mins
38	Radeon RX 6650XT Navi 23 [Radeon RX 6650XT]	AMD	Navi 23	1,054,750	74,924	14.08	1 ^hrs 42 ^mins
39	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,013,055	75,312	13.45	1 ^hrs 47 ^mins

40	Radeon RX 6700/6700XT/6800M Navi 22 XT-XL [Radeon RX 6700/6700XT/6800M]	AMD	Navi 22 XT-XL	970,264	72,162	13.45	1 ^hrs 47 ^mins
41	P104-100 GP104 [P104-100]	Nvidia	GP104	955,015	73,479	13.00	1 ^hrs 51 ^mins
42	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	845,239	67,607	12.50	1 ^hrs 55 ^mins
43	GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER]	Nvidia	TU116	823,411	70,282	11.72	2 ^hrs 3 ^mins
44	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	678,890	65,931	10.30	2 ^hrs 20 ^mins
45	Quadro P2200 GP106GL [Quadro P2200]	Nvidia	GP106GL	411,390	56,215	7.32	3 ^hrs 17 ^mins
46	GeForce GTX 1050 Ti GP107 [GeForce GTX 1050 Ti] 2138	Nvidia	GP107	332,562	52,016	6.39	3 ^hrs 45 ^mins
47	RX 470/480/570/580/590 Ellesmere XT [RX 470/480/570/580/590]	AMD	Ellesmere XT	322,499	51,558	6.26	3 ^hrs 50 ^mins
48	GeForce MX450 TU117M [GeForce MX450]	Nvidia	TU117M	246,169	47,525	5.18	4 ^hrs 38 ^mins
49	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	233,983	45,985	5.09	4 ^hrs 43 ^mins
50	Tesla K40m GK110 [Tesla K40m] 5046	Nvidia	GK110	232,165	47,401	4.90	4 ^hrs 54 ^mins
51	R7 370/R9 270X/370X Curacao XT/Trinidad XT [R7 370/R9 270X/370X]	AMD	Curacao XT/Trinidad XT	76,747	33,167	2.31	10 ^hrs 22 ^mins
52	Radeon 540/540X/550/550X/RX 540X/550/550X Lexa PRO [Radeon 540/540X/550/550X/RX 540X/550/550X]	AMD	Lexa PRO	40,844	25,142	1.62	14 ^hrs 46 ^mins

Research: CANCER Folding Project #14949

Project Summary AI Beta

Project team

Work unit

Official Project Description

Hardware Performance for Project 14949

GPU PPD Averages

Research: CANCER Folding Project #14949

Project Summary AI Beta

Project team

Work unit

Related projects

GPU PPD Averages