PROJECT #13458 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
https://www.youtube.com/watch?v=VnyaAmM1nhE These projects are rapid sprints of relative alchemical free energy calculations for prioritizing compound designs from chemists from the COVID Moonshot for synthesis.
Top-scoring molecules will be made and tested in a laboratory by the COVID Moonshot as it works to develop an open science patent-free inexpensive therapy for COVID-19 that shuts down the essential SARS-CoV-2 main viral protease.
The COVID Moonshot has already made and tested hundreds of compounds, and is pursuing several good lead series.
You can see their progress in real time here:
https://covid.postera.ai/covid/submissions/compounds
To learn more about what the Moonshot is and how it came about, you can read our blog post or watch this video.
In addition to helping us prioritize compounds, you can help us purchase more compounds for synthesis at cost from Enamine by sponsoring our GoFundMe page for patent-free open science COVID-19 drug discovery! This is a radical new approach to drug discovery that aims to rapidly produce inexpensive new therapies.
SARS-CoV-2 main viral potease (Mpro) with ligand bound, from the RCSB.
PROJECT INFO
Manager(s): Dr. John Chodera
Institution: Memorial Sloan Kettering Cancer Center
Project URL: http://choderalab.org
PROJECT WORK UNIT SUMMARY
Atoms: 89,709
Core: OPENMM_22
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Monday, 20 March 2023 06:14:58
|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 6,559,089 | 302,180 | 21.71 | 1 hrs 6 mins |
| 2 | GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti] |
Nvidia | GA102 | 6,082,793 | 295,597 | 20.58 | 1 hrs 10 mins |
| 3 | GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate] |
Nvidia | GA102 | 5,555,998 | 285,484 | 19.46 | 1 hrs 14 mins |
| 4 | GeForce RTX 3080 GA102 [GeForce RTX 3080] |
Nvidia | GA102 | 5,498,840 | 285,864 | 19.24 | 1 hrs 15 mins |
| 5 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 4,477,262 | 268,683 | 16.66 | 1 hrs 26 mins |
| 6 | GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti] |
Nvidia | GA104 | 4,287,397 | 264,441 | 16.21 | 1 hrs 29 mins |
| 7 | GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448 |
Nvidia | TU102 | 4,123,728 | 260,389 | 15.84 | 2 hrs 31 mins |
| 8 | GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate] |
Nvidia | GA104 | 4,048,616 | 260,537 | 15.54 | 2 hrs 33 mins |
| 9 | GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068 |
Nvidia | TU104 | 3,726,326 | 253,114 | 14.72 | 2 hrs 38 mins |
| 10 | GeForce RTX 3070 GA104 [GeForce RTX 3070] |
Nvidia | GA104 | 3,438,260 | 245,310 | 14.02 | 2 hrs 43 mins |
| 11 | GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER] |
Nvidia | TU104 | 3,277,862 | 242,979 | 13.49 | 2 hrs 47 mins |
| 12 | GeForce RTX 3070 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3070 Mobile / Max-Q 8GB/16GB] |
Nvidia | GA104M | 3,119,552 | 239,055 | 13.05 | 2 hrs 50 mins |
| 13 | GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218 |
Nvidia | TU104 | 3,034,675 | 237,808 | 12.76 | 2 hrs 53 mins |
| 14 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 2,983,933 | 235,494 | 12.67 | 2 hrs 54 mins |
| 15 | GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti] |
Nvidia | GA104 | 2,808,166 | 230,375 | 12.19 | 2 hrs 58 mins |
| 16 | GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate] |
Nvidia | GA104 | 2,666,479 | 213,029 | 12.52 | 2 hrs 55 mins |
| 17 | GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465 |
Nvidia | TU106 | 2,530,435 | 220,440 | 11.48 | 2 hrs 5 mins |
| 18 | GeForce RTX 3060 GA106 [GeForce RTX 3060] |
Nvidia | GA106 | 2,518,269 | 220,397 | 11.43 | 2 hrs 6 mins |
| 19 | Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT] |
AMD | Navi 21 | 2,309,597 | 216,039 | 10.69 | 2 hrs 15 mins |
| 20 | GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER] |
Nvidia | TU106 | 2,246,404 | 213,809 | 10.51 | 2 hrs 17 mins |
| 21 | GeForce RTX 2060 TU104 [GeForce RTX 2060] |
Nvidia | TU104 | 2,070,928 | 208,527 | 9.93 | 2 hrs 25 mins |
| 22 | Quadro RTX 4000 TU104GL [Quadro RTX 4000] |
Nvidia | TU104GL | 2,044,721 | 207,546 | 9.85 | 2 hrs 26 mins |
| 23 | GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q] |
Nvidia | GA106M | 1,911,524 | 196,447 | 9.73 | 2 hrs 28 mins |
| 24 | Quadro RTX 5000 TU104GL [Quadro RTX 5000] |
Nvidia | TU104GL | 1,862,106 | 164,328 | 11.33 | 2 hrs 7 mins |
| 25 | TITAN X GP102 [TITAN X] 6144 |
Nvidia | GP102 | 1,845,445 | 172,339 | 10.71 | 2 hrs 14 mins |
| 26 | GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate] |
Nvidia | GA106 | 1,824,879 | 193,644 | 9.42 | 3 hrs 33 mins |
| 27 | GeForce RTX 2070 TU106 [GeForce RTX 2070] M 6497 |
Nvidia | TU106 | 1,790,620 | 193,472 | 9.26 | 3 hrs 36 mins |
| 28 | Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT] |
AMD | Navi 21 | 1,720,154 | 194,806 | 8.83 | 3 hrs 43 mins |
| 29 | Quadro RTX 6000/8000 TU102GL [Quadro RTX 6000/8000] |
Nvidia | TU102GL | 1,537,863 | 191,092 | 8.05 | 3 hrs 59 mins |
| 30 | GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile] |
Nvidia | TU106M | 1,430,803 | 175,215 | 8.17 | 3 hrs 56 mins |
| 31 | GeForce RTX 2060 TU106 [Geforce RTX 2060] |
Nvidia | TU106 | 1,408,847 | 169,780 | 8.30 | 3 hrs 54 mins |
| 32 | Radeon VII Vega 20 [Radeon VII] 13,284 |
AMD | Vega 20 | 1,372,106 | 181,466 | 7.56 | 3 hrs 10 mins |
| 33 | GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873 |
Nvidia | GP104 | 1,366,425 | 180,517 | 7.57 | 3 hrs 10 mins |
| 34 | GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile] 4608 |
Nvidia | TU106M | 1,359,358 | 181,307 | 7.50 | 3 hrs 12 mins |
| 35 | GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER] |
Nvidia | TU116 | 1,297,234 | 177,267 | 7.32 | 3 hrs 17 mins |
| 36 | GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463 |
Nvidia | GP104 | 1,262,209 | 173,719 | 7.27 | 3 hrs 18 mins |
| 37 | GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186 |
Nvidia | GP104 | 1,219,290 | 171,111 | 7.13 | 3 hrs 22 mins |
| 38 | GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632 |
Nvidia | GM200 | 1,215,486 | 173,602 | 7.00 | 3 hrs 26 mins |
| 39 | Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT] |
AMD | Navi 10 | 1,038,850 | 159,699 | 6.51 | 4 hrs 41 mins |
| 40 | Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64] |
AMD | Vega 10 XL/XT | 1,019,591 | 164,240 | 6.21 | 4 hrs 52 mins |
| 41 | GeForce GTX 1660 TU116 [GeForce GTX 1660] |
Nvidia | TU116 | 1,017,086 | 164,484 | 6.18 | 4 hrs 53 mins |
| 42 | Radeon RX 6700/6700 XT / 6800M Navi 22 [Radeon RX 6700/6700 XT / 6800M] |
AMD | Navi 22 | 919,217 | 156,752 | 5.86 | 4 hrs 6 mins |
| 43 | P104-100 GP104 [P104-100] |
Nvidia | GP104 | 824,876 | 153,355 | 5.38 | 4 hrs 28 mins |
| 44 | GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372 |
Nvidia | GP106 | 778,195 | 150,934 | 5.16 | 5 hrs 39 mins |
| 45 | GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER] |
Nvidia | TU116 | 742,304 | 148,633 | 4.99 | 5 hrs 48 mins |
| 46 | Radeon RX 6600/6600 XT/6600M Navi 23 [Radeon RX 6600/6600 XT/6600M] |
AMD | Navi 23 | 708,298 | 145,736 | 4.86 | 5 hrs 56 mins |
| 47 | GeForce GTX 1650 TU117 [GeForce GTX 1650] 3091 |
Nvidia | TU117 | 668,963 | 143,686 | 4.66 | 5 hrs 9 mins |
| 48 | GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935 |
Nvidia | GP106 | 662,785 | 142,542 | 4.65 | 5 hrs 10 mins |
| 49 | GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q] |
Nvidia | TU117M | 508,201 | 131,423 | 3.87 | 6 hrs 12 mins |
| 50 | Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590] |
AMD | Ellesmere XT | 441,693 | 120,796 | 3.66 | 7 hrs 34 mins |
| 51 | GeForce GTX 1650 TU117 [GeForce GTX 1650] |
Nvidia | TU117 | 363,595 | 113,666 | 3.20 | 8 hrs 30 mins |
| 52 | T600 TU117GL [T600] |
Intel | TU117GL | 347,220 | 112,770 | 3.08 | 8 hrs 48 mins |
| 53 | Radeon RX Vega M XL [Radeon RX Vega M XL] |
AMD | Vega | 151,597 | 84,747 | 1.79 | 13 hrs 25 mins |
| 54 | Polaris11 Baffin [Polaris11] |
AMD | Baffin | 25,094 | 54,400 | 0.46 | 52 hrs 2 mins |
| 55 | Radeon APU A4-6000 R2 Mullins [Radeon APU A4-6000 R2] |
AMD | Mullins | 9,834 | 54,400 | 0.18 | 133 hrs 46 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Monday, 20 March 2023 06:14:58
|
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|