PROJECT #13454 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
https://www.youtube.com/watch?v=VnyaAmM1nhEThese projects are rapid sprints of relative alchemical free energy calculations for prioritizing compound designs from chemists from the COVID Moonshot for synthesis.
Top-scoring molecules will be made and tested in a laboratory by the COVID Moonshot as it works to develop an open science patent-free inexpensive therapy for COVID-19 that shuts down the essential SARS-CoV-2 main viral protease.
The COVID Moonshot has already made and tested hundreds of compounds, and is pursuing several good lead series.
You can see their progress in real time here:
https://covid.postera.ai/covid/submissions/compounds
To learn more about what the Moonshot is and how it came about, you can read our blog post or watch this video.
In addition to helping us prioritize compounds, you can help us purchase more compounds for synthesis at cost from Enamine by sponsoring our GoFundMe page for patent-free open science COVID-19 drug discovery! This is a radical new approach to drug discovery that aims to rapidly produce inexpensive new therapies.
SARS-CoV-2 main viral potease (Mpro) with ligand bound, from the RCSB.
PROJECT INFO
Manager(s): Dr. John Chodera
Institution: Memorial Sloan Kettering Cancer Center
Project URL: http://choderalab.org
PROJECT WORK UNIT SUMMARY
Atoms: 89,709
Core: OPENMM_22
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Saturday, 01 April 2023 12:14:52
|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 6,247,864 | 298,052 | 20.96 | 1 hrs 9 mins |
| 2 | GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti] |
Nvidia | GA102 | 5,571,189 | 280,765 | 19.84 | 1 hrs 13 mins |
| 3 | GeForce RTX 3080 10GB / 20GB GA102 [GeForce RTX 3080 10GB / 20GB] |
Nvidia | GA102 | 4,616,300 | 272,180 | 16.96 | 1 hrs 25 mins |
| 4 | GeForce RTX 3080 GA102 [GeForce RTX 3080] |
Nvidia | GA102 | 4,613,959 | 271,856 | 16.97 | 1 hrs 25 mins |
| 5 | GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448 |
Nvidia | TU102 | 4,240,629 | 263,537 | 16.09 | 1 hrs 29 mins |
| 6 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 3,855,707 | 254,242 | 15.17 | 2 hrs 35 mins |
| 7 | GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti] |
Nvidia | GA104 | 3,795,601 | 255,109 | 14.88 | 2 hrs 37 mins |
| 8 | Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT] |
AMD | Navi 21 | 3,709,323 | 251,372 | 14.76 | 2 hrs 38 mins |
| 9 | TITAN Xp GP102 [TITAN Xp] 12150 |
Nvidia | GP102 | 3,147,483 | 239,692 | 13.13 | 2 hrs 50 mins |
| 10 | GeForce RTX 3070 GA104 [GeForce RTX 3070] |
Nvidia | GA104 | 3,145,491 | 239,178 | 13.15 | 2 hrs 49 mins |
| 11 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 3,114,212 | 238,160 | 13.08 | 2 hrs 50 mins |
| 12 | GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218 |
Nvidia | TU104 | 2,886,134 | 230,663 | 12.51 | 2 hrs 55 mins |
| 13 | GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER] |
Nvidia | TU104 | 2,771,867 | 229,806 | 12.06 | 2 hrs 59 mins |
| 14 | Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT] |
AMD | Navi 21 | 2,622,125 | 222,375 | 11.79 | 2 hrs 2 mins |
| 15 | GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068 |
Nvidia | TU104 | 2,605,827 | 224,766 | 11.59 | 2 hrs 4 mins |
| 16 | GeForce RTX 2080 TU104 [GeForce RTX 2080] |
Nvidia | TU104 | 2,565,279 | 223,623 | 11.47 | 2 hrs 6 mins |
| 17 | GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465 |
Nvidia | TU106 | 2,562,946 | 224,095 | 11.44 | 2 hrs 6 mins |
| 18 | GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti] |
Nvidia | GA104 | 2,405,745 | 219,146 | 10.98 | 2 hrs 11 mins |
| 19 | GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER] |
Nvidia | TU106 | 2,123,999 | 208,611 | 10.18 | 2 hrs 21 mins |
| 20 | GeForce RTX 2060 TU104 [GeForce RTX 2060] |
Nvidia | TU104 | 1,859,684 | 201,004 | 9.25 | 3 hrs 36 mins |
| 21 | GeForce RTX 2070 TU106 [GeForce RTX 2070] M 6497 |
Nvidia | TU106 | 1,843,353 | 197,349 | 9.34 | 3 hrs 34 mins |
| 22 | Radeon VII Vega 20 [Radeon VII] 13,284 |
AMD | Vega 20 | 1,725,170 | 196,389 | 8.78 | 3 hrs 44 mins |
| 23 | GeForce RTX 2060 TU106 [Geforce RTX 2060] |
Nvidia | TU106 | 1,690,257 | 190,641 | 8.87 | 3 hrs 42 mins |
| 24 | GeForce RTX 3060 GA106 [GeForce RTX 3060] |
Nvidia | GA106 | 1,666,819 | 192,907 | 8.64 | 3 hrs 47 mins |
| 25 | GeForce RTX 3070 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3070 Mobile / Max-Q 8GB/16GB] |
Nvidia | GA104M | 1,646,382 | 192,861 | 8.54 | 3 hrs 49 mins |
| 26 | GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873 |
Nvidia | GP104 | 1,638,067 | 189,476 | 8.65 | 3 hrs 47 mins |
| 27 | Radeon RX 6700/6700 XT / 6800M Navi 22 [Radeon RX 6700/6700 XT / 6800M] |
AMD | Navi 22 | 1,613,384 | 182,931 | 8.82 | 3 hrs 43 mins |
| 28 | GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463 |
Nvidia | GP104 | 1,558,369 | 189,093 | 8.24 | 3 hrs 55 mins |
| 29 | GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186 |
Nvidia | GP104 | 1,499,167 | 187,054 | 8.01 | 3 hrs 60 mins |
| 30 | GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile] |
Nvidia | TU106M | 1,368,360 | 176,364 | 7.76 | 3 hrs 6 mins |
| 31 | GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q] |
Nvidia | GA106M | 1,353,433 | 171,479 | 7.89 | 3 hrs 2 mins |
| 32 | Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT] |
AMD | Navi 10 | 1,275,009 | 176,034 | 7.24 | 3 hrs 19 mins |
| 33 | GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER] |
Nvidia | TU116 | 1,229,280 | 172,001 | 7.15 | 3 hrs 21 mins |
| 34 | Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64] |
AMD | Vega 10 XL/XT | 1,132,404 | 170,635 | 6.64 | 4 hrs 37 mins |
| 35 | GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti] |
Nvidia | TU116 | 1,047,955 | 166,353 | 6.30 | 4 hrs 49 mins |
| 36 | GeForce GTX 1660 TU116 [GeForce GTX 1660] |
Nvidia | TU116 | 926,946 | 159,322 | 5.82 | 4 hrs 8 mins |
| 37 | GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632 |
Nvidia | GM200 | 879,138 | 131,596 | 6.68 | 4 hrs 36 mins |
| 38 | GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372 |
Nvidia | GP106 | 820,105 | 152,526 | 5.38 | 4 hrs 28 mins |
| 39 | P104-100 GP104 [P104-100] |
Nvidia | GP104 | 789,323 | 151,190 | 5.22 | 5 hrs 36 mins |
| 40 | GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER] |
Nvidia | TU116 | 674,511 | 143,311 | 4.71 | 5 hrs 6 mins |
| 41 | GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935 |
Nvidia | GP106 | 606,308 | 138,672 | 4.37 | 5 hrs 29 mins |
| 42 | Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590] |
AMD | Ellesmere XT | 597,577 | 136,796 | 4.37 | 5 hrs 30 mins |
| 43 | P106-100 GP106 [P106-100] |
Nvidia | GP106 | 581,561 | 136,380 | 4.26 | 6 hrs 38 mins |
| 44 | Quadro T2000 Mobile / Max-Q TU117GLM [Quadro T2000 Mobile / Max-Q] |
Nvidia | TU117GLM | 485,723 | 128,785 | 3.77 | 6 hrs 22 mins |
| 45 | GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984 |
Nvidia | TU116 | 434,679 | 119,740 | 3.63 | 7 hrs 37 mins |
| 46 | Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series] |
AMD | Hawaii | 428,927 | 123,380 | 3.48 | 7 hrs 54 mins |
| 47 | GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q] |
Nvidia | TU117M | 382,104 | 117,549 | 3.25 | 7 hrs 23 mins |
| 48 | Radeon RX Vega gfx902 raven [Radeon RX Vega gfx902] |
AMD | raven | 341,571 | 74,748 | 4.57 | 5 hrs 15 mins |
| 49 | Radeon R9 Fury X Fiji XT [Radeon R9 Fury X] |
AMD | Fiji XT | 274,743 | 69,134 | 3.97 | 6 hrs 2 mins |
| 50 | Radeon R9 200/300 Series Tonga [Radeon R9 200/300 Series] |
AMD | Tonga | 227,670 | 100,151 | 2.27 | 11 hrs 33 mins |
| 51 | Radeon RX Vega M XL [Radeon RX Vega M XL] |
AMD | Vega | 201,537 | 95,870 | 2.10 | 11 hrs 25 mins |
| 52 | Radeon R9 200 Series Hawaii [Radeon R9 200 Series] |
AMD | Hawaii | 151,444 | 87,848 | 1.72 | 14 hrs 55 mins |
| 53 | Quadro P1000 GP107GL [Quadro P1000] |
Nvidia | GP107GL | 132,442 | 83,374 | 1.59 | 15 hrs 6 mins |
| 54 | Radeon R7/R6 360 Series Bonaire [Radeon R7/R6 360 Series] |
AMD | Bonaire | 64,740 | 54,400 | 1.19 | 20 hrs 10 mins |
| 55 | Radeon R9 200/HD 7900/8970 Tahiti XT [Radeon R9 200/HD 7900/8970] |
AMD | Tahiti XT | 34,458 | 58,597 | 0.59 | 41 hrs 49 mins |
| 56 | Radeon R7 250/HD 7700 R575A [Radeon R7 250/HD 7700] |
AMD | R575A | 22,838 | 54,400 | 0.42 | 57 hrs 10 mins |
| 57 | Radeon APU A4-6000 R2 Mullins [Radeon APU A4-6000 R2] |
AMD | Mullins | 10,955 | 54,400 | 0.20 | 119 hrs 11 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Saturday, 01 April 2023 12:14:52
|
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|