PROJECT #13447 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
https://www.youtube.com/watch?v=VnyaAmM1nhEThese projects are rapid sprints of relative alchemical free energy calculations for prioritizing compound designs from chemists from the COVID Moonshot for synthesis. Top-scoring molecules will be made and tested in a laboratory by the COVID Moonshot as it works to develop an open science patent-free inexpensive therapy for COVID-19 that shuts down the essential SARS-CoV-2 main viral protease.
The COVID Moonshot has already made and tested hundreds of compounds, and is pursuing several good lead series. You can see their progress in real time here:
https://covid.postera.ai/covid/submissions/compounds
To learn more about what the Moonshot is and how it came about, you can read our blog post or watch this video.
In addition to helping us prioritize compounds, you can help us purchase more compounds for synthesis at cost from Enamine by sponsoring our GoFundMe page for patent-free open science COVID-19 drug discovery! This is a radical new approach to drug discovery that aims to rapidly produce inexpensive new therapies.
SARS-CoV-2 main viral potease (Mpro) with ligand bound, from the RCSB
PROJECT INFO
Manager(s): Dr. John Chodera
Institution: Memorial Sloan Kettering Cancer Center
Project URL: http://choderalab.org
PROJECT WORK UNIT SUMMARY
Atoms: 4,082
Core: OPENMM_22
Status: Beta
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Thursday, 15 April 2021 19:59:50
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
---|---|---|---|---|---|---|---|
1 | GeForce GTX 1070 Mobile GP104M [GeForce GTX 1070 Mobile] |
Nvidia | GP104M | 759,268 | 16,969 | 44.74 | 1 hrs 32 mins |
2 | GeForce GTX 960 GM206 [GeForce GTX 960] 2308 |
Nvidia | GM206 | 545,023 | 15,073 | 36.16 | 1 hrs 40 mins |
3 | GeForce GTX 970 GM204 [GeForce GTX 970] 3494 |
Nvidia | GM204 | 468,627 | 14,460 | 32.41 | 1 hrs 44 mins |
4 | Quadro M2200 GM206 [Quadro M2200] |
Nvidia | GM206 | 464,887 | 14,528 | 32.00 | 1 hrs 45 mins |
5 | GeForce GTX 660 Ti GK104 [GeForce GTX 660 Ti] 2634 |
Nvidia | GK104 | 349,931 | 12,811 | 27.31 | 1 hrs 53 mins |
6 | GeForce GTX 1050 Ti Mobile GP107M [GeForce GTX 1050 Ti Mobile] |
Nvidia | GP107M | 327,786 | 12,378 | 26.48 | 1 hrs 54 mins |
7 | GeForce GTX 1050 Mobile GP107M [GeForce GTX 1050 Mobile] |
Nvidia | GP107M | 271,301 | 12,246 | 22.15 | 1 hrs 5 mins |
8 | Quadro K2200 GM107GL [Quadro K2200] |
Nvidia | GM107GL | 227,299 | 11,288 | 20.14 | 1 hrs 12 mins |
9 | GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389 |
Nvidia | GM107 | 195,776 | 10,326 | 18.96 | 1 hrs 16 mins |
10 | GeForce GT 1030 GP108 [GeForce GT 1030] 1127 |
Nvidia | GP108 | 190,643 | 10,507 | 18.14 | 1 hrs 19 mins |
11 | GTX 650 Ti Boost GK106 [GTX 650 Ti Boost] |
GK106 | 190,290 | 10,603 | 17.95 | 1 hrs 20 mins | |
12 | Quadro K1200 GM107GL [Quadro K1200] |
Nvidia | GM107GL | 153,050 | 9,857 | 15.53 | 2 hrs 33 mins |
13 | GeForce GTX 770 GK104 [GeForce GTX 770] 3213 |
Nvidia | GK104 | 118,969 | 7,825 | 15.20 | 2 hrs 35 mins |
14 | Quadro P620 GP107GL [Quadro P620] |
Nvidia | GP107GL | 110,174 | 8,985 | 12.26 | 2 hrs 57 mins |
15 | GeForce GTX 760 GK104 [GeForce GTX 760] 2258 |
Nvidia | GK104 | 104,741 | 8,163 | 12.83 | 2 hrs 52 mins |
16 | GeForce 920M GK208 [GeForce 920M] |
Nvidia | GK208 | 81,543 | 8,085 | 10.09 | 2 hrs 23 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Thursday, 15 April 2021 19:59:50
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
---|
Legal Information: This sites use is for entertainment purposes only and comes with no guarantees or warranties in its use or related to any data displayed, collected or calcuated. This site is not affilated with folding@home or any folding team or GPU / CPU company in any official capacity and is an enthusiast creation in support of folding@home and the users / teams folding data for the greater good.
Please Note: By using this site, and / or our chrome extension you understand that you may be periodically providing information such as your IP, stats regarding use of our site, and folding@home GPU / CPU model, Work Unit ID and PPD estimate data when using our Chrome extention to the site developer for site optimization and PPD related data displayed on the site.
IF YOU DO NOT WISH TO CONTRIBUTE DATA TO THE PPD DATABASE PLEASE UNINSTALL OUR PLUGIN/TOOLS AND DISCONTINUE USE OF THIS SITE IMMEDIATELY.