PROJECT #13444 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

https://www.youtube.com/watch?v=VnyaAmM1nhEThese projects are rapid sprints of relative alchemical free energy calculations for prioritizing compound designs from chemists from the COVID Moonshot for synthesis. Top-scoring molecules will be made and tested in a laboratory by the COVID Moonshot as it works to develop an open science patent-free inexpensive therapy for COVID-19 that shuts down the essential SARS-CoV-2 main viral protease

The COVID Moonshot has already made and tested hundreds of compounds, and is pursuing several good lead series. You can see their progress in real time here:
https://covid.postera.ai/covid/submissions/compounds

To learn more about what the Moonshot is and how it came about, you can read our blog post or watch this video.

In addition to helping us prioritize compounds, you can help us purchase more compounds for synthesis at cost from Enamine by sponsoring our GoFundMe page for patent-free open science COVID-19 drug discovery! This is a radical new approach to drug discovery that aims to rapidly produce inexpensive new therapies.

 

SARS-CoV-2 main viral protease

SARS-CoV-2 main viral potease (Mpro) with ligand bound, from the RCSB

PROJECT INFO

Manager(s): Dr. John Chodera

Institution: Memorial Sloan Kettering Cancer Center

Project URL: http://choderalab.org

PROJECT WORK UNIT SUMMARY

Atoms: 89,709

Core: OPENMM_22

Status: Beta

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 25 February 2021 23:25:28

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 3090
GA102 [GeForce RTX 3090]
Nvidia GA102 5,449,476 284,408 19.16 1 hrs 15 mins
2 GeForce RTX 3080 10GB / 20GB
GA102 [GeForce RTX 3080 10GB / 20GB]
Nvidia GA102 5,048,664 279,208 18.08 1 hrs 20 mins
3 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448
Nvidia TU102 4,374,392 266,746 16.40 1 hrs 28 mins
4 GeForce RTX 2080 Ti
TU102 [GeForce RTX 2080 Ti] M 13448
Nvidia TU102 3,609,435 250,710 14.40 2 hrs 40 mins
5 GeForce RTX 3070
GA104 [GeForce RTX 3070]
Nvidia GA104 3,215,297 239,326 13.43 2 hrs 47 mins
6 GeForce RTX 2080 Rev. A
TU104 [GeForce RTX 2080 Rev. A] 10068
Nvidia TU104 3,004,082 237,175 12.67 2 hrs 54 mins
7 Radeon RX 6800/6800 XT / 6900 XT
Navi 21 [Radeon RX 6800/6800 XT / 6900 XT]
AMD Navi 21 2,990,094 233,820 12.79 2 hrs 53 mins
8 GeForce RTX 2080 Super
TU104 [GeForce RTX 2080 SUPER]
Nvidia TU104 2,775,310 228,906 12.12 2 hrs 59 mins
9 GeForce GTX 1080 Ti
GP102 [GeForce GTX 1080 Ti] 11380
Nvidia GP102 2,661,158 226,992 11.72 2 hrs 3 mins
10 GeForce RTX 2070 SUPER
TU104 [GeForce RTX 2070 SUPER] 8218
Nvidia TU104 2,652,926 226,485 11.71 2 hrs 3 mins
11 GeForce RTX 3060 Ti
GA104 [GeForce RTX 3060 Ti]
Nvidia GA104 2,580,971 221,453 11.65 2 hrs 4 mins
12 GeForce RTX 2070 Rev. A
TU106 [GeForce RTX 2070 Rev. A] M 7465
Nvidia TU106 2,306,931 216,126 10.67 2 hrs 15 mins
13 Quadro RTX 6000/8000
TU102GL [Quadro RTX 6000/8000]
Nvidia TU102GL 2,294,877 214,837 10.68 2 hrs 15 mins
14 GeForce RTX 2080
TU104 [GeForce RTX 2080]
Nvidia TU104 2,247,427 211,693 10.62 2 hrs 16 mins
15 GeForce RTX 2060 Super
TU106 [GeForce RTX 2060 SUPER]
Nvidia TU106 2,019,381 204,809 9.86 2 hrs 26 mins
16 GeForce RTX 2070
TU106 [GeForce RTX 2070] M 6497
Nvidia TU106 1,949,934 200,952 9.70 2 hrs 28 mins
17 Radeon VII
Vega 20 [Radeon VII] 13,284
AMD Vega 20 1,936,300 202,623 9.56 3 hrs 31 mins
18 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 1,805,640 199,080 9.07 3 hrs 39 mins
19 GeForce RTX 2060
TU106 [Geforce RTX 2060]
Nvidia TU106 1,690,090 194,693 8.68 3 hrs 46 mins
20 Quadro RTX 4000
TU104GL [Quadro RTX 4000]
Nvidia TU104GL 1,625,822 192,635 8.44 3 hrs 51 mins
21 GeForce GTX 1080
GP104 [GeForce GTX 1080] 8873
Nvidia GP104 1,507,011 186,070 8.10 3 hrs 58 mins
22 GeForce GTX 1070 Ti
GP104 [GeForce GTX 1070 Ti] 8186
Nvidia GP104 1,422,873 184,581 7.71 3 hrs 7 mins
23 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 1,360,951 180,502 7.54 3 hrs 11 mins
24 GeForce GTX 1660 Ti
TU116 [GeForce GTX 1660 Ti]
Nvidia TU116 1,308,641 177,925 7.36 3 hrs 16 mins
25 GeForce RTX 2060 Mobile
TU106M [GeForce RTX 2060 Mobile]
Nvidia TU106M 1,157,932 152,141 7.61 3 hrs 9 mins
26 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 1,138,440 168,961 6.74 4 hrs 34 mins
27 GeForce GTX 980 Ti
GM200 [GeForce GTX 980 Ti] 5632
Nvidia GM200 1,079,568 167,204 6.46 4 hrs 43 mins
28 Radeon RX Vega 56/64
Vega 10 XL/XT [Radeon RX Vega 56/64]
AMD Vega 10 XL/XT 984,842 162,604 6.06 4 hrs 58 mins
29 GeForce GTX 1660
TU116 [GeForce GTX 1660]
Nvidia TU116 933,733 156,268 5.98 4 hrs 1 mins
30 Radeon RX 5600 OEM/5600 XT/5700/5700 XT
Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]
AMD Navi 10 862,991 154,057 5.60 4 hrs 17 mins
31 P104-100
GP104 [P104-100]
Nvidia GP104 774,913 150,328 5.15 5 hrs 39 mins
32 GeForce GTX 1070
GP104 [GeForce GTX 1070]
Nvidia GP104 740,057 147,831 5.01 5 hrs 48 mins
33 GeForce GTX 1650 SUPER
TU116 [GeForce GTX 1650 SUPER]
Nvidia TU116 721,024 143,275 5.03 5 hrs 46 mins
34 GeForce GTX 1060 6GB
GP106 [GeForce GTX 1060 6GB] 4372
Nvidia GP106 650,930 138,804 4.69 5 hrs 7 mins
35 GeForce GTX 1060 3GB
GP106 [GeForce GTX 1060 3GB] 3935
Nvidia GP106 641,899 140,912 4.56 5 hrs 16 mins
36 GeForce GTX 1650 Ti Mobile
TU116M [GeForce GTX 1650 Ti Mobile]
Nvidia TU116M 623,143 136,027 4.58 5 hrs 14 mins
37 Radeon RX 5500/5500M / Pro 5500M
Navi 14 [Radeon RX 5500/5500M / Pro 5500M]
AMD Navi 14 555,975 134,479 4.13 6 hrs 48 mins
38 GeForce GTX 1650
TU116 [GeForce GTX 1650] 2984
Nvidia TU116 551,699 134,229 4.11 6 hrs 50 mins
39 P106-100
GP106 [P106-100]
Nvidia GP106 536,873 133,113 4.03 6 hrs 57 mins
40 Quadro T2000 Mobile / Max-Q
TU117GLM [Quadro T2000 Mobile / Max-Q]
Nvidia TU117GLM 504,036 129,051 3.91 6 hrs 9 mins
41 GeForce GTX 1650 Mobile / Max-Q
TU117M [GeForce GTX 1650 Mobile / Max-Q]
Nvidia TU117M 493,557 129,097 3.82 6 hrs 17 mins
42 Radeon RX 470/480/570/580/590
Ellesmere XT [Radeon RX 470/480/570/580/590]
AMD Ellesmere XT 480,529 125,403 3.83 6 hrs 16 mins
43 Radeon R9 200/300X Series
Hawaii [Radeon R9 200/300X Series]
AMD Hawaii 444,900 124,957 3.56 7 hrs 44 mins
44 Radeon R9 200/300 Series
Hawaii [Radeon R9 200/300 Series]
AMD Hawaii 441,401 119,788 3.68 7 hrs 31 mins
45 Radeon R9 Fury X
Fiji XT [Radeon R9 Fury X]
AMD Fiji XT 419,626 120,047 3.50 7 hrs 52 mins
46 P106-090
GP106 [P106-090]
Nvidia GP106 334,759 113,704 2.94 8 hrs 9 mins
47 GeForce GTX 1050 LP
GP107 [GeForce GTX 1050 LP] 1862
Nvidia GP107 329,352 113,069 2.91 8 hrs 14 mins
48 Radeon R9 200/300 Series
Tonga [Radeon R9 200/300 Series]
AMD Tonga 185,424 93,324 1.99 12 hrs 5 mins
49 Quadro P1000
GP107GL [Quadro P1000]
Nvidia GP107GL 147,074 84,337 1.74 14 hrs 46 mins
50 Radeon R9 280/HD 7900/8950
Tahiti PRO [Radeon R9 280/HD 7900/8950]
AMD Tahiti PRO 145,230 86,448 1.68 14 hrs 17 mins
51 Radeon RX Vega M XL
[Radeon RX Vega M XL]
AMD Vega 127,444 67,370 1.89 13 hrs 41 mins
52 Ryzen 4900HS mobile
Renoir [Ryzen 4900HS mobile]
AMD Renoir 65,241 61,502 1.06 23 hrs 37 mins
53 Radeon R7/R6 360 Series
Bonaire [Radeon R7/R6 360 Series]
AMD Bonaire 59,798 54,400 1.10 22 hrs 50 mins
54 Ryzen vega 8 mobile
Raven [Ryzen vega 8 mobile]
AMD Raven 46,476 54,400 0.85 28 hrs 6 mins
55 Radeon RX Vega gfx902
raven [Radeon RX Vega gfx902]
AMD raven 41,133 54,400 0.76 32 hrs 44 mins
56 Radeon APU A4-6000 R2
Mullins [Radeon APU A4-6000 R2]
AMD Mullins 6,923 54,400 0.13 189 hrs 35 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 25 February 2021 23:25:29

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
 

Legal Information: This sites use is for entertainment purposes only and comes with no guarantees or warranties in its use or related to any data displayed, collected or calcuated. This site is not affilated with folding@home or any folding team or GPU / CPU company in any official capacity and is an enthusiast creation in support of folding@home and the users / teams folding data for the greater good.

Please Note: By using this site, and / or our chrome extension you understand that you may be periodically providing information such as your IP, stats regarding use of our site, and folding@home GPU / CPU model, Work Unit ID and PPD estimate data when using our Chrome extention to the site developer for site optimization and PPD related data displayed on the site.

IF YOU DO NOT WISH TO CONTRIBUTE DATA TO THE PPD DATABASE PLEASE UNINSTALL OUR PLUGIN/TOOLS AND DISCONTINUE USE OF THIS SITE IMMEDIATELY.