PROJECT #13456 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
https://www.youtube.com/watch?v=VnyaAmM1nhEThese projects are rapid sprints of relative alchemical free energy calculations for prioritizing compound designs from chemists from the COVID Moonshot for synthesis.
Top-scoring molecules will be made and tested in a laboratory by the COVID Moonshot as it works to develop an open science patent-free inexpensive therapy for COVID-19 that shuts down the essential SARS-CoV-2 main viral protease.
The COVID Moonshot has already made and tested hundreds of compounds, and is pursuing several good lead series.
You can see their progress in real time here:
https://covid.postera.ai/covid/submissions/compounds
To learn more about what the Moonshot is and how it came about, you can read our blog post or watch this video.
In addition to helping us prioritize compounds, you can help us purchase more compounds for synthesis at cost from Enamine by sponsoring our GoFundMe page for patent-free open science COVID-19 drug discovery! This is a radical new approach to drug discovery that aims to rapidly produce inexpensive new therapies.
SARS-CoV-2 main viral potease (Mpro) with ligand bound, from the RCSB.
PROJECT INFO
Manager(s): Dr. John Chodera
Institution: Memorial Sloan Kettering Cancer Center
Project URL: http://choderalab.org
PROJECT WORK UNIT SUMMARY
Atoms: 89,709
Core: OPENMM_22
Status: Beta
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Saturday, 01 April 2023 12:14:52
|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 5,423,202 | 283,683 | 19.12 | 1 hrs 15 mins |
| 2 | GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti] |
Nvidia | GA102 | 4,242,809 | 269,952 | 15.72 | 2 hrs 32 mins |
| 3 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 3,826,207 | 254,611 | 15.03 | 2 hrs 36 mins |
| 4 | GeForce RTX 3080 GA102 [GeForce RTX 3080] |
Nvidia | GA102 | 3,386,817 | 244,879 | 13.83 | 2 hrs 44 mins |
| 5 | GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate] |
Nvidia | GA102 | 3,118,665 | 239,981 | 13.00 | 2 hrs 51 mins |
| 6 | Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT] |
AMD | Navi 21 | 3,071,435 | 237,216 | 12.95 | 2 hrs 51 mins |
| 7 | GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448 |
Nvidia | TU102 | 2,940,940 | 227,501 | 12.93 | 2 hrs 51 mins |
| 8 | GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti] |
Nvidia | GA104 | 2,899,598 | 240,539 | 12.05 | 2 hrs 59 mins |
| 9 | TITAN Xp GP102 [TITAN Xp] 12150 |
Nvidia | GP102 | 2,885,773 | 239,882 | 12.03 | 2 hrs 60 mins |
| 10 | GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER] |
Nvidia | TU104 | 2,812,723 | 236,354 | 11.90 | 2 hrs 1 mins |
| 11 | GeForce RTX 3070 GA104 [GeForce RTX 3070] |
Nvidia | GA104 | 2,722,638 | 226,011 | 12.05 | 2 hrs 60 mins |
| 12 | Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT] |
AMD | Navi 21 | 2,707,629 | 251,649 | 10.76 | 2 hrs 14 mins |
| 13 | GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068 |
Nvidia | TU104 | 2,484,546 | 220,075 | 11.29 | 2 hrs 8 mins |
| 14 | GeForce RTX 2080 TU104 [GeForce RTX 2080] |
Nvidia | TU104 | 2,324,804 | 220,142 | 10.56 | 2 hrs 16 mins |
| 15 | GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER] |
Nvidia | TU106 | 2,244,283 | 212,620 | 10.56 | 2 hrs 16 mins |
| 16 | Tesla P40 GP102GL [Tesla P40] 11760 |
Nvidia | GP102GL | 2,223,540 | 214,254 | 10.38 | 2 hrs 19 mins |
| 17 | GeForce RTX 3070 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3070 Mobile / Max-Q 8GB/16GB] |
Nvidia | GA104M | 1,982,806 | 246,654 | 8.04 | 3 hrs 59 mins |
| 18 | GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465 |
Nvidia | TU106 | 1,972,324 | 201,557 | 9.79 | 2 hrs 27 mins |
| 19 | GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti] |
Nvidia | GA104 | 1,785,000 | 198,182 | 9.01 | 3 hrs 40 mins |
| 20 | GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q] |
Nvidia | GA106M | 1,767,074 | 194,627 | 9.08 | 3 hrs 39 mins |
| 21 | GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873 |
Nvidia | GP104 | 1,738,538 | 194,645 | 8.93 | 3 hrs 41 mins |
| 22 | GeForce RTX 2060 TU106 [Geforce RTX 2060] |
Nvidia | TU106 | 1,727,161 | 198,821 | 8.69 | 3 hrs 46 mins |
| 23 | GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate] |
Nvidia | GA104 | 1,716,069 | 195,558 | 8.78 | 3 hrs 44 mins |
| 24 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 1,678,205 | 165,547 | 10.14 | 2 hrs 22 mins |
| 25 | GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463 |
Nvidia | GP104 | 1,345,247 | 180,881 | 7.44 | 3 hrs 14 mins |
| 26 | Radeon RX 6600/6600 XT/6600M Navi 23 [Radeon RX 6600/6600 XT/6600M] |
AMD | Navi 23 | 1,325,529 | 179,488 | 7.39 | 3 hrs 15 mins |
| 27 | GeForce RTX 3060 GA106 [GeForce RTX 3060] |
Nvidia | GA106 | 1,270,829 | 177,581 | 7.16 | 3 hrs 21 mins |
| 28 | GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER] |
Nvidia | TU116 | 1,145,569 | 168,577 | 6.80 | 4 hrs 32 mins |
| 29 | GeForce GTX 1660 TU116 [GeForce GTX 1660] |
Nvidia | TU116 | 1,113,887 | 174,686 | 6.38 | 4 hrs 46 mins |
| 30 | GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti] |
Nvidia | TU116 | 1,092,469 | 168,912 | 6.47 | 4 hrs 43 mins |
| 31 | Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64] |
AMD | Vega 10 XL/XT | 1,077,727 | 166,448 | 6.47 | 4 hrs 42 mins |
| 32 | Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT] |
AMD | Navi 10 | 1,057,641 | 164,500 | 6.43 | 4 hrs 44 mins |
| 33 | GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile] |
Nvidia | TU106M | 1,047,482 | 131,257 | 7.98 | 3 hrs 0 mins |
| 34 | Radeon RX 6700/6700 XT / 6800M Navi 22 [Radeon RX 6700/6700 XT / 6800M] |
AMD | Navi 22 | 991,030 | 122,818 | 8.07 | 3 hrs 58 mins |
| 35 | GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372 |
Nvidia | GP106 | 699,742 | 146,445 | 4.78 | 5 hrs 1 mins |
| 36 | GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER] |
Nvidia | TU116 | 682,762 | 138,319 | 4.94 | 5 hrs 52 mins |
| 37 | GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984 |
Nvidia | TU116 | 548,681 | 161,302 | 3.40 | 7 hrs 3 mins |
| 38 | Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590] |
AMD | Ellesmere XT | 492,679 | 129,459 | 3.81 | 6 hrs 18 mins |
| 39 | Radeon R9 200/300 Series Hawaii [Radeon R9 200/300 Series] |
AMD | Hawaii | 462,544 | 128,375 | 3.60 | 7 hrs 40 mins |
| 40 | GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q] |
Nvidia | TU117M | 453,493 | 135,625 | 3.34 | 7 hrs 11 mins |
| 41 | Quadro T2000 Mobile / Max-Q TU117GLM [Quadro T2000 Mobile / Max-Q] |
Nvidia | TU117GLM | 433,990 | 122,728 | 3.54 | 7 hrs 47 mins |
| 42 | Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series] |
AMD | Hawaii | 264,077 | 109,180 | 2.42 | 10 hrs 55 mins |
| 43 | Radeon R9 200/300 Series Tonga [Radeon R9 200/300 Series] |
AMD | Tonga | 208,719 | 97,238 | 2.15 | 11 hrs 11 mins |
| 44 | Radeon R7/R6 360 Series Bonaire [Radeon R7/R6 360 Series] |
AMD | Bonaire | 66,339 | 56,886 | 1.17 | 21 hrs 35 mins |
| 45 | Ryzen vega 8 mobile Raven [Ryzen vega 8 mobile] |
AMD | Raven | 52,692 | 54,400 | 0.97 | 25 hrs 47 mins |
| 46 | Radeon APU A4-6000 R2 Mullins [Radeon APU A4-6000 R2] |
AMD | Mullins | 6,212 | 58,422 | 0.11 | 226 hrs 43 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Saturday, 01 April 2023 12:14:52
|
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|