PROJECT #16608 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This series of GPU projects to simulation the Nonstructural protein 12 (nsp12) and Nonstructural protein 14 (nsp14) complexes.  We will screen existing FDA-approved NTP analog drugs (e.g. Ribirine). We aim to repurpose drugs that can inhibit SARS-CoV-2 replication

16600: Nonstructural protein 14 and 10 (nsp14-ExoN & nsp 10) of the SARS-CoV-2 in complex with a short nascent RNA containing Cladribine at 3'-terminal.

16602: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP in active site

16603: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP.

16604: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and GTP.

16605: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP.

16606: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP.

16607: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP.

16608: RdRp and helicase of SARS-CoV-2 in complex with dsRNA

16609: RdRp and helicase of SARS-CoV-2 in complex with dsRNA

PROJECT INFO

Manager(s): Prof. Xuhui Huang

Institution: Hong Kong University of Science and Technology

PROJECT WORK UNIT SUMMARY

Atoms: 473,039

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 27 September 2021 17:59:06

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 3090
GA102 [GeForce RTX 3090]
Nvidia GA102 7,824,590 681,609 11.48 2 hrs 5 mins
2 GeForce RTX 3080 Ti
GA102 [GeForce RTX 3080 Ti]
Nvidia GA102 7,651,377 680,112 11.25 2 hrs 8 mins
3 GeForce RTX 3080 Lite Hash Rate
GA102 [GeForce RTX 3080 Lite Hash Rate]
Nvidia GA102 6,393,579 640,748 9.98 2 hrs 24 mins
4 GeForce RTX 3080
GA102 [GeForce RTX 3080]
Nvidia GA102 6,385,212 642,115 9.94 2 hrs 25 mins
5 GeForce RTX 3070 Ti
GA104 [GeForce RTX 3070 Ti]
Nvidia GA104 5,307,232 597,962 8.88 3 hrs 42 mins
6 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448
Nvidia TU102 4,413,900 566,578 7.79 3 hrs 5 mins
7 GeForce RTX 3070
GA104 [GeForce RTX 3070]
Nvidia GA104 4,062,034 552,556 7.35 3 hrs 16 mins
8 Radeon RX 6900 XT
Navi 21 [Radeon RX 6900 XT]
AMD Navi 21 3,839,736 537,564 7.14 3 hrs 22 mins
9 GeForce RTX 2080 Ti
TU102 [GeForce RTX 2080 Ti] M 13448
Nvidia TU102 3,790,456 460,392 8.23 3 hrs 55 mins
10 GeForce RTX 2070 SUPER
TU104 [GeForce RTX 2070 SUPER] 8218
Nvidia TU104 3,053,014 503,520 6.06 4 hrs 57 mins
11 GeForce RTX 2080
TU104 [GeForce RTX 2080]
Nvidia TU104 2,964,442 495,842 5.98 4 hrs 1 mins
12 TITAN Xp
GP102 [TITAN Xp] 12150
Nvidia GP102 2,941,048 496,574 5.92 4 hrs 3 mins
13 GeForce RTX 3060 Ti Lite Hash Rate
GA104 [GeForce RTX 3060 Ti Lite Hash Rate]
Nvidia GA104 2,862,052 491,908 5.82 4 hrs 7 mins
14 GeForce RTX 2080 Rev. A
TU104 [GeForce RTX 2080 Rev. A] 10068
Nvidia TU104 2,842,808 490,795 5.79 4 hrs 9 mins
15 GeForce RTX 2080 Super
TU104 [GeForce RTX 2080 SUPER]
Nvidia TU104 2,823,311 490,943 5.75 4 hrs 10 mins
16 GeForce RTX 2070 Rev. A
TU106 [GeForce RTX 2070 Rev. A] M 7465
Nvidia TU106 2,757,021 485,701 5.68 4 hrs 14 mins
17 GeForce RTX 3070 Mobile / Max-Q 8GB/16GB
GA104M [GeForce RTX 3070 Mobile / Max-Q 8GB/16GB]
Nvidia GA104M 2,610,444 477,923 5.46 4 hrs 24 mins
18 GeForce GTX 1080 Ti
GP102 [GeForce GTX 1080 Ti] 11380
Nvidia GP102 2,455,608 466,447 5.26 5 hrs 34 mins
19 Radeon VII
Vega 20 [Radeon VII] 13,284
AMD Vega 20 2,365,412 460,365 5.14 5 hrs 40 mins
20 GeForce RTX 2060 Super
TU106 [GeForce RTX 2060 SUPER]
Nvidia TU106 2,326,474 443,911 5.24 5 hrs 35 mins
21 TITAN X
GP102 [TITAN X] 6144
Nvidia GP102 2,204,132 451,394 4.88 5 hrs 55 mins
22 Radeon RX 6700/6700 XT / 6800M
Navi 22 [Radeon RX 6700/6700 XT / 6800M]
AMD Navi 22 2,197,993 450,267 4.88 5 hrs 55 mins
23 GeForce RTX 3060 Mobile / Max-Q
GA106M [GeForce RTX 3060 Mobile / Max-Q]
Nvidia GA106M 1,942,201 432,021 4.50 5 hrs 20 mins
24 GeForce RTX 2060
TU106 [Geforce RTX 2060]
Nvidia TU106 1,922,076 429,949 4.47 5 hrs 22 mins
25 Tesla P40
GP102GL [Tesla P40] 11760
Nvidia GP102GL 1,826,916 422,749 4.32 6 hrs 33 mins
26 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 1,762,792 417,994 4.22 6 hrs 41 mins
27 GeForce GTX 1080
GP104 [GeForce GTX 1080] 8873
Nvidia GP104 1,722,929 414,677 4.15 6 hrs 47 mins
28 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 1,440,883 391,742 3.68 7 hrs 32 mins
29 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 1,322,733 379,270 3.49 7 hrs 53 mins
30 GeForce RTX 2060 Mobile
TU106M [GeForce RTX 2060 Mobile]
Nvidia TU106M 1,313,831 378,344 3.47 7 hrs 55 mins
31 Radeon RX 5600 OEM/5600 XT/5700/5700 XT
Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]
AMD Navi 10 1,298,041 377,566 3.44 7 hrs 59 mins
32 Radeon RX Vega 56/64
Vega 10 XL/XT [Radeon RX Vega 56/64]
AMD Vega 10 XL/XT 1,240,936 369,458 3.36 7 hrs 9 mins
33 GeForce GTX 1660 Ti
TU116 [GeForce GTX 1660 Ti]
Nvidia TU116 1,217,446 363,890 3.35 7 hrs 10 mins
34 GeForce GTX 1660
TU116 [GeForce GTX 1660]
Nvidia TU116 1,013,081 348,168 2.91 8 hrs 15 mins
35 GeForce GTX 1060 6GB
GP106 [GeForce GTX 1060 6GB] 4372
Nvidia GP106 784,667 319,647 2.45 10 hrs 47 mins
36 GeForce GTX 970
GM204 [GeForce GTX 970] 3494
Nvidia GM204 729,396 312,652 2.33 10 hrs 17 mins
37 Tesla P4
GP104GL [Tesla P4] 5704
Nvidia GP104GL 728,361 311,366 2.34 10 hrs 16 mins
38 GeForce GTX 1650
TU116 [GeForce GTX 1650] 2984
Nvidia TU116 522,447 279,626 1.87 13 hrs 51 mins
39 Quadro T2000 Mobile / Max-Q
TU117GLM [Quadro T2000 Mobile / Max-Q]
Nvidia TU117GLM 509,148 276,477 1.84 13 hrs 2 mins
40 Radeon RX 470/480/570/580/590
Ellesmere XT [Radeon RX 470/480/570/580/590]
AMD Ellesmere XT 446,267 264,993 1.68 14 hrs 15 mins
41 GeForce GTX 960
GM206 [GeForce GTX 960] 2308
Nvidia GM206 315,377 233,306 1.35 18 hrs 45 mins
42 GeForce GTX 950
GM206 [GeForce GTX 950] 1572
Nvidia GM206 303,725 231,594 1.31 18 hrs 18 mins
43 Radeon RX Vega M XL
[Radeon RX Vega M XL]
AMD Vega 198,685 185,062 1.07 22 hrs 21 mins
44 Quadro P620
GP107GL [Quadro P620]
Nvidia GP107GL 174,319 193,920 0.90 27 hrs 42 mins
45 GeForce GTX 750 Ti
GM107 [GeForce GTX 750 Ti] 1389
Nvidia GM107 170,117 187,358 0.91 26 hrs 26 mins
46 GeForce GT 1030
GP108 [GeForce GT 1030] 1127
Nvidia GP108 139,090 179,718 0.77 31 hrs 1 mins
47 Quadro K1200
GM107GL [Quadro K1200]
Nvidia GM107GL 111,253 166,842 0.67 36 hrs 60 mins
48 GeForce GTX 960M
GM107 [GeForce GTX 960M] 1439
Nvidia GM107 106,060 125,196 0.85 28 hrs 20 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 27 September 2021 17:59:06

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make