PROJECT #16602 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This series of GPU projects to simulation the Nonstructural protein 12 (nsp12) and Nonstructural protein 14 (nsp14) complexes.

We will screen existing FDA-approved NTP analog drugs (e.g.

Ribirine).

We aim to repurpose drugs that can inhibit SARS-CoV-2 replication 16600: Nonstructural protein 14 and 10 (nsp14-ExoN & nsp 10) of the SARS-CoV-2 in complex with a short nascent RNA containing Cladribine at 3'-terminal. 16602: Nonstructural protein 12, 7 and 8of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP in active site.

PROJECT INFO

Manager(s): Prof. Xuhui Huang

Institution: Hong Kong University of Science and Technology

PROJECT WORK UNIT SUMMARY

Atoms: 208,201

Core: OPENMM_22

Status: Beta

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 03 October 2022 12:16:41

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	5,978,360	89,952	66.46	0 ^hrs 22 ^mins
2	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	2,713,127	69,370	39.11	1 ^hrs 37 ^mins
3	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	2,641,624	95,571	27.64	1 ^hrs 52 ^mins
4	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	2,510,326	67,806	37.02	1 ^hrs 39 ^mins
5	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,265,547	65,385	34.65	1 ^hrs 42 ^mins
6	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,987,624	62,113	32.00	1 ^hrs 45 ^mins
7	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	859,495	47,562	18.07	1 ^hrs 20 ^mins
8	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	844,636	47,317	17.85	1 ^hrs 21 ^mins
9	Radeon R9 200/300 Series Hawaii [Radeon R9 200/300 Series]	AMD	Hawaii	524,359	39,424	13.30	2 ^hrs 48 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA