PROJECT #16604 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This series of GPU projects to simulation the Nonstructural protein 12 (nsp12) and Nonstructural protein 14 (nsp14) complexes.

We will screen existing FDA-approved NTP analog drugs (e.g.

Ribirine).

We aim to repurpose drugs that can inhibit SARS-CoV-2 replication 16600: Nonstructural protein 14 and 10 (nsp14-ExoN & nsp 10) of the SARS-CoV-2 in complex with a short nascent RNA containing Cladribine at 3'-terminal. 16602: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP in active site 16603: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP. 16604: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and GTP..

PROJECT INFO

Manager(s): Prof. Xuhui Huang

Institution: Hong Kong University of Science and Technology

PROJECT WORK UNIT SUMMARY

Atoms: 208,512

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 07 February 2023 12:14:59

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	7,150,641	496,905	14.39	2 ^hrs 40 ^mins
2	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	6,403,158	484,001	13.23	2 ^hrs 49 ^mins
3	GeForce RTX 3080 10GB / 20GB GA102 [GeForce RTX 3080 10GB / 20GB]	Nvidia	GA102	6,107,050	474,464	12.87	2 ^hrs 52 ^mins
4	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	5,358,495	456,198	11.75	2 ^hrs 3 ^mins
5	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	4,803,774	438,456	10.96	2 ^hrs 11 ^mins
6	Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT]	AMD	Navi 21	4,274,329	422,963	10.11	2 ^hrs 22 ^mins
7	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	4,181,885	420,023	9.96	2 ^hrs 25 ^mins
8	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,093,161	415,911	9.84	2 ^hrs 26 ^mins
9	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,347,943	388,561	8.62	3 ^hrs 47 ^mins
10	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,923,069	370,800	7.88	3 ^hrs 3 ^mins
11	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	2,898,948	369,300	7.85	3 ^hrs 3 ^mins
12	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	2,865,850	366,921	7.81	3 ^hrs 4 ^mins
13	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	2,777,919	348,600	7.97	3 ^hrs 1 ^mins
14	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,457,635	351,138	7.00	3 ^hrs 26 ^mins
15	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465	Nvidia	TU106	2,420,669	349,725	6.92	3 ^hrs 28 ^mins
16	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,354,057	346,443	6.79	4 ^hrs 32 ^mins
17	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,271,424	342,542	6.63	4 ^hrs 37 ^mins
18	Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT]	AMD	Navi 21	2,193,369	335,659	6.53	4 ^hrs 40 ^mins
19	GeForce RTX 3060 GA106 [GeForce RTX 3060]	Nvidia	GA106	2,069,492	329,878	6.27	4 ^hrs 50 ^mins
20	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,765,535	315,452	5.60	4 ^hrs 17 ^mins
21	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,748,585	314,561	5.56	4 ^hrs 19 ^mins
22	GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q]	Nvidia	GA106M	1,573,053	302,983	5.19	5 ^hrs 37 ^mins
23	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,282,690	282,626	4.54	5 ^hrs 17 ^mins
24	GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile]	Nvidia	TU106M	1,274,536	283,230	4.50	5 ^hrs 20 ^mins
25	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,248,396	280,637	4.45	5 ^hrs 24 ^mins
26	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,153,858	273,163	4.22	6 ^hrs 41 ^mins
27	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,084,870	239,827	4.52	5 ^hrs 18 ^mins
28	Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]	AMD	Navi 10	1,066,640	264,563	4.03	6 ^hrs 57 ^mins
29	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	1,026,510	263,538	3.90	6 ^hrs 10 ^mins
30	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	904,923	252,043	3.59	7 ^hrs 41 ^mins
31	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	886,775	250,176	3.54	7 ^hrs 46 ^mins
32	P104-100 GP104 [P104-100]	Nvidia	GP104	865,884	248,513	3.48	7 ^hrs 53 ^mins
33	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	790,904	238,465	3.32	7 ^hrs 14 ^mins
34	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	744,709	235,239	3.17	8 ^hrs 35 ^mins
35	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	695,061	230,985	3.01	8 ^hrs 59 ^mins
36	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	615,253	221,128	2.78	9 ^hrs 38 ^mins
37	GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER]	Nvidia	TU116	596,353	219,329	2.72	9 ^hrs 50 ^mins
38	P106-100 GP106 [P106-100]	Nvidia	GP106	563,455	215,348	2.62	9 ^hrs 10 ^mins
39	Radeon R9 Fury X Fiji XT [Radeon R9 Fury X]	AMD	Fiji XT	553,593	183,058	3.02	8 ^hrs 56 ^mins
40	Radeon R9 200/300 Series Hawaii [Radeon R9 200/300 Series]	AMD	Hawaii	522,804	205,698	2.54	9 ^hrs 27 ^mins
41	GeForce GTX 1650 Ti Mobile TU116M [GeForce GTX 1650 Ti Mobile]	Nvidia	TU116M	488,052	205,409	2.38	10 ^hrs 6 ^mins
42	Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590]	AMD	Ellesmere XT	434,577	192,014	2.26	11 ^hrs 36 ^mins
43	GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984	Nvidia	TU116	426,482	193,388	2.21	11 ^hrs 53 ^mins
44	Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series]	AMD	Hawaii	381,093	188,606	2.02	12 ^hrs 53 ^mins
45	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	310,845	171,783	1.81	13 ^hrs 16 ^mins
46	Radeon R9 280/HD 7900/8950 Tahiti PRO [Radeon R9 280/HD 7900/8950]	AMD	Tahiti PRO	285,058	171,293	1.66	14 ^hrs 25 ^mins
47	GeForce GTX 1050 Mobile GP107M [GeForce GTX 1050 Mobile]	Nvidia	GP107M	273,890	169,401	1.62	15 ^hrs 51 ^mins
48	GeForce GTX 1050 Ti Mobile GP107M [GeForce GTX 1050 Ti Mobile]	Nvidia	GP107M	255,474	165,455	1.54	16 ^hrs 33 ^mins
49	GeForce GTX 690 GK104 [GeForce GTX 690] 3130	Nvidia	GK104	229,724	159,830	1.44	17 ^hrs 42 ^mins
50	Radeon RX Vega M XL [Radeon RX Vega M XL]	AMD	Vega	176,523	146,495	1.20	20 ^hrs 55 ^mins
51	GeForce GTX 660 Ti GK104 [GeForce GTX 660 Ti] 2634	Nvidia	GK104	167,922	143,607	1.17	21 ^hrs 31 ^mins
52	Quadro P620 GP107GL [Quadro P620]	Nvidia	GP107GL	144,065	136,840	1.05	23 ^hrs 48 ^mins
53	GeForce GTX 660 GK106 [GeForce GTX 660]	Nvidia	GK106	141,119	136,039	1.04	23 ^hrs 8 ^mins
54	Radeon HD 7800 Pitcairn [Radeon HD 7800]	AMD	Pitcairn	140,114	135,581	1.03	23 ^hrs 13 ^mins
55	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	118,106	127,541	0.93	26 ^hrs 55 ^mins
56	GeForce GT 1030 GP108 [GeForce GT 1030] 1127	Nvidia	GP108	109,324	124,604	0.88	27 ^hrs 21 ^mins
57	Quadro K1200 GM107GL [Quadro K1200]	Nvidia	GM107GL	92,312	117,775	0.78	31 ^hrs 37 ^mins
58	Radeon RX Vega gfx902 raven [Radeon RX Vega gfx902]	AMD	raven	31,324	58,300	0.54	45 ^hrs 40 ^mins
59	Radeon R7 250/HD 7700 R575A [Radeon R7 250/HD 7700]	AMD	R575A	24,218	58,300	0.42	58 ^hrs 47 ^mins
60	Radeon RX 5500/5500M / Pro 5500M Navi 14 [Radeon RX 5500/5500M / Pro 5500M]	AMD	Navi 14	23,418	58,300	0.40	60 ^hrs 45 ^mins
61	GeForce 920M GK208 [GeForce 920M]	Nvidia	GK208	21,371	58,300	0.37	65 ^hrs 28 ^mins
62	GeForce GT 710 GK208B [GeForce GT 710] 366	Nvidia	GK208B	19,982	60,015	0.33	72 ^hrs 5 ^mins
63	Ryzen vega 8 mobile Raven [Ryzen vega 8 mobile]	AMD	Raven	17,225	58,300	0.30	81 ^hrs 14 ^mins
64	GeForce GTX 560 Ti GF114 [GeForce GTX 560 Ti]	Nvidia	GF114	11,181	58,300	0.19	125 ^hrs 8 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA