PROJECT #16603 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This series of GPU projects to simulation the Nonstructural protein 12 (nsp12) and Nonstructural protein 14 (nsp14) complexes.

We will screen existing FDA-approved NTP analog drugs (e.g.

Ribirine).

We aim to repurpose drugs that can inhibit SARS-CoV-2 replication 16600: Nonstructural protein 14 and 10 (nsp14-ExoN & nsp 10) of the SARS-CoV-2 in complex with a short nascent RNA containing Cladribine at 3'-terminal. 16602: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP in active site 16603: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP. 16604: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and GTP..

PROJECT INFO

Manager(s): Prof. Xuhui Huang

Institution: Hong Kong University of Science and Technology

PROJECT WORK UNIT SUMMARY

Atoms: 208,201

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 31 January 2023 00:15:03

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	7,277,748	493,774	14.74	2 ^hrs 38 ^mins
2	GeForce RTX 3080 10GB / 20GB GA102 [GeForce RTX 3080 10GB / 20GB]	Nvidia	GA102	5,309,115	446,887	11.88	2 ^hrs 1 ^mins
3	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	4,848,062	432,402	11.21	2 ^hrs 8 ^mins
4	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,456,796	420,385	10.60	2 ^hrs 16 ^mins
5	Quadro RTX 6000/8000 TU102GL [Quadro RTX 6000/8000]	Nvidia	TU102GL	4,242,330	413,382	10.26	2 ^hrs 20 ^mins
6	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	3,153,171	374,428	8.42	3 ^hrs 51 ^mins
7	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	2,871,625	362,338	7.93	3 ^hrs 2 ^mins
8	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465	Nvidia	TU106	2,656,327	355,014	7.48	3 ^hrs 12 ^mins
9	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,528,271	348,327	7.26	3 ^hrs 18 ^mins
10	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,423,697	341,940	7.09	3 ^hrs 23 ^mins
11	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,151,473	329,923	6.52	4 ^hrs 41 ^mins
12	GeForce RTX 3060 GA106 [GeForce RTX 3060]	Nvidia	GA106	2,050,965	324,858	6.31	4 ^hrs 48 ^mins
13	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,048,165	324,378	6.31	4 ^hrs 48 ^mins
14	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,703,479	305,810	5.57	4 ^hrs 19 ^mins
15	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,384,418	285,352	4.85	5 ^hrs 57 ^mins
16	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,245,644	275,622	4.52	5 ^hrs 19 ^mins
17	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,209,404	272,388	4.44	5 ^hrs 24 ^mins
18	Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]	AMD	Navi 10	1,162,578	268,730	4.33	6 ^hrs 33 ^mins
19	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,096,359	263,135	4.17	6 ^hrs 46 ^mins
20	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	1,024,971	257,969	3.97	6 ^hrs 2 ^mins
21	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	893,533	246,465	3.63	7 ^hrs 37 ^mins
22	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	875,961	245,066	3.57	7 ^hrs 43 ^mins
23	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	845,737	241,980	3.50	7 ^hrs 52 ^mins
24	P104-100 GP104 [P104-100]	Nvidia	GP104	839,665	241,383	3.48	7 ^hrs 54 ^mins
25	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	602,372	215,811	2.79	9 ^hrs 36 ^mins
26	P106-100 GP106 [P106-100]	Nvidia	GP106	553,501	210,052	2.64	9 ^hrs 6 ^mins
27	Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series]	AMD	Hawaii	426,958	192,824	2.21	11 ^hrs 50 ^mins
28	Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590]	AMD	Ellesmere XT	399,687	188,514	2.12	11 ^hrs 19 ^mins
29	GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984	Nvidia	TU116	362,191	182,171	1.99	12 ^hrs 4 ^mins
30	GeForce GTX 960 GM206 [GeForce GTX 960] 2308	Nvidia	GM206	295,232	170,611	1.73	14 ^hrs 52 ^mins
31	GeForce GTX 1050 Ti Mobile GP107M [GeForce GTX 1050 Ti Mobile]	Nvidia	GP107M	267,932	165,303	1.62	15 ^hrs 48 ^mins
32	Radeon R9 200/300 Series Hawaii [Radeon R9 200/300 Series]	AMD	Hawaii	240,201	118,879	2.02	12 ^hrs 53 ^mins
33	GeForce GTX 660 Ti GK104 [GeForce GTX 660 Ti] 2634	Nvidia	GK104	213,022	152,337	1.40	17 ^hrs 10 ^mins
34	Radeon HD 7800 Pitcairn [Radeon HD 7800]	AMD	Pitcairn	136,730	131,650	1.04	23 ^hrs 6 ^mins
35	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	135,832	131,630	1.03	23 ^hrs 15 ^mins
36	Quadro K2200 GM107GL [Quadro K2200]	Nvidia	GM107GL	131,123	130,084	1.01	24 ^hrs 49 ^mins
37	Radeon Rx 270/370 Curacao Pro [Radeon Rx 270/370]	AMD	Curacao Pro	121,175	117,528	1.03	23 ^hrs 17 ^mins
38	Radeon R7 250/HD 7700 R575A [Radeon R7 250/HD 7700]	AMD	R575A	24,750	56,630	0.44	55 ^hrs 55 ^mins
39	Radeon APU A4-6000 R2 Mullins [Radeon APU A4-6000 R2]	AMD	Mullins	5,315	56,630	0.09	256 ^hrs 43 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA