PROJECT #16606 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This series of GPU projects to simulation the Nonstructural protein 12 (nsp12) and Nonstructural protein 14 (nsp14) complexes.

We will screen existing FDA-approved NTP analog drugs (e.g.

Ribirine).

We aim to repurpose drugs that can inhibit SARS-CoV-2 replication 16600: Nonstructural protein 14 and 10 (nsp14-ExoN & nsp 10) of the SARS-CoV-2 in complex with a short nascent RNA containing Cladribine at 3'-terminal. 16602: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP in active site 16603: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP. 16604: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and GTP. 16605: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP. 16606: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP. 16607: Nonstructural protein 12, 7 and 8 of the SARS-CoV-2 in complex with a short nascent RNA , template RNA and ATP..

PROJECT INFO

Manager(s): Prof. Xuhui Huang

Institution: Hong Kong University of Science and Technology

PROJECT WORK UNIT SUMMARY

Atoms: 208,201

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 04 December 2022 18:13:27

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	6,611,098	472,977	13.98	2 ^hrs 43 ^mins
2	GeForce RTX 3080 10GB / 20GB GA102 [GeForce RTX 3080 10GB / 20GB]	Nvidia	GA102	5,438,066	448,952	12.11	2 ^hrs 59 ^mins
3	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	5,128,796	440,459	11.64	2 ^hrs 4 ^mins
4	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	4,350,462	415,453	10.47	2 ^hrs 18 ^mins
5	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	3,981,359	404,692	9.84	2 ^hrs 26 ^mins
6	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,165,131	374,368	8.45	3 ^hrs 50 ^mins
7	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	2,801,117	360,336	7.77	3 ^hrs 5 ^mins
8	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	2,788,563	359,566	7.76	3 ^hrs 6 ^mins
9	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,748,420	357,503	7.69	3 ^hrs 7 ^mins
10	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	2,704,644	355,815	7.60	3 ^hrs 9 ^mins
11	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,602,114	350,588	7.42	3 ^hrs 14 ^mins
12	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465	Nvidia	TU106	2,319,812	338,678	6.85	4 ^hrs 30 ^mins
13	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,232,390	333,626	6.69	4 ^hrs 35 ^mins
14	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,190,376	332,429	6.59	4 ^hrs 39 ^mins
15	Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT]	AMD	Navi 21	2,086,517	324,286	6.43	4 ^hrs 44 ^mins
16	TITAN Xp GP102 [TITAN Xp] 12150	Nvidia	GP102	2,037,845	324,467	6.28	4 ^hrs 49 ^mins
17	GeForce RTX 3060 GA106 [GeForce RTX 3060]	Nvidia	GA106	1,877,076	314,834	5.96	4 ^hrs 2 ^mins
18	GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q]	Nvidia	GA106M	1,822,035	314,450	5.79	4 ^hrs 9 ^mins
19	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,701,803	305,431	5.57	4 ^hrs 18 ^mins
20	Radeon RX 6700/6700 XT / 6800M Navi 22 [Radeon RX 6700/6700 XT / 6800M]	AMD	Navi 22	1,611,412	298,132	5.41	4 ^hrs 26 ^mins
21	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,550,420	289,992	5.35	4 ^hrs 29 ^mins
22	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,273,584	277,428	4.59	5 ^hrs 14 ^mins
23	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,248,340	275,067	4.54	5 ^hrs 17 ^mins
24	GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile]	Nvidia	TU106M	1,207,866	273,869	4.41	5 ^hrs 27 ^mins
25	Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]	AMD	Navi 10	1,131,679	265,863	4.26	6 ^hrs 38 ^mins
26	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,103,068	259,611	4.25	6 ^hrs 39 ^mins
27	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	991,309	255,340	3.88	6 ^hrs 11 ^mins
28	GeForce RTX 3070 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3070 Mobile / Max-Q 8GB/16GB]	Nvidia	GA104M	985,800	253,857	3.88	6 ^hrs 11 ^mins
29	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	956,285	249,967	3.83	6 ^hrs 16 ^mins
30	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	947,810	250,367	3.79	6 ^hrs 20 ^mins
31	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	927,790	248,682	3.73	6 ^hrs 26 ^mins
32	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	858,923	241,221	3.56	7 ^hrs 44 ^mins
33	P104-100 GP104 [P104-100]	Nvidia	GP104	847,880	241,937	3.50	7 ^hrs 51 ^mins
34	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	801,876	237,885	3.37	7 ^hrs 7 ^mins
35	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	678,562	224,555	3.02	8 ^hrs 57 ^mins
36	Radeon R9 Fury X Fiji XT [Radeon R9 Fury X]	AMD	Fiji XT	571,801	192,188	2.98	8 ^hrs 4 ^mins
37	P106-100 GP106 [P106-100]	Nvidia	GP106	547,406	209,420	2.61	9 ^hrs 11 ^mins
38	GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER]	Nvidia	TU116	526,140	206,510	2.55	9 ^hrs 25 ^mins
39	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	520,625	198,677	2.62	9 ^hrs 10 ^mins
40	Radeon R9 200/300 Series Hawaii [Radeon R9 200/300 Series]	AMD	Hawaii	520,413	200,441	2.60	9 ^hrs 15 ^mins
41	Quadro T2000 Mobile / Max-Q TU117GLM [Quadro T2000 Mobile / Max-Q]	Nvidia	TU117GLM	428,008	192,158	2.23	11 ^hrs 47 ^mins
42	GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984	Nvidia	TU116	409,815	190,064	2.16	11 ^hrs 8 ^mins
43	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	409,454	189,520	2.16	11 ^hrs 7 ^mins
44	Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590]	AMD	Ellesmere XT	397,303	178,246	2.23	11 ^hrs 46 ^mins
45	Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series]	AMD	Hawaii	393,217	187,537	2.10	11 ^hrs 27 ^mins
46	GeForce GTX 1050 LP GP107 [GeForce GTX 1050 LP] 1862	Nvidia	GP107	288,484	169,103	1.71	14 ^hrs 4 ^mins
47	GeForce GTX 960 GM206 [GeForce GTX 960] 2308	Nvidia	GM206	287,603	168,944	1.70	14 ^hrs 6 ^mins
48	Radeon R9 280/HD 7900/8950 Tahiti PRO [Radeon R9 280/HD 7900/8950]	AMD	Tahiti PRO	255,058	151,507	1.68	14 ^hrs 15 ^mins
49	GeForce GTX 660 Ti GK104 [GeForce GTX 660 Ti] 2634	Nvidia	GK104	209,897	151,755	1.38	17 ^hrs 21 ^mins
50	GeForce GTX 1050 Ti Mobile GP107M [GeForce GTX 1050 Ti Mobile]	Nvidia	GP107M	178,492	144,405	1.24	19 ^hrs 25 ^mins
51	Radeon RX Vega M XL [Radeon RX Vega M XL]	AMD	Vega	176,840	143,806	1.23	20 ^hrs 31 ^mins
52	GeForce GTX 660 GK106 [GeForce GTX 660]	Nvidia	GK106	134,028	129,134	1.04	23 ^hrs 7 ^mins
53	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	131,427	129,737	1.01	24 ^hrs 41 ^mins
54	Quadro K2200 GM107GL [Quadro K2200]	Nvidia	GM107GL	129,847	129,516	1.00	24 ^hrs 56 ^mins
55	Quadro K1200 GM107GL [Quadro K1200]	Nvidia	GM107GL	88,527	114,240	0.77	31 ^hrs 58 ^mins
56	GeForce GT 1030 GP108 [GeForce GT 1030] 1127	Nvidia	GP108	62,130	87,469	0.71	34 ^hrs 47 ^mins
57	Radeon R7 250/HD 7700 R575A [Radeon R7 250/HD 7700]	AMD	R575A	23,756	56,730	0.42	57 ^hrs 19 ^mins
58	Radeon RX Vega gfx902 raven [Radeon RX Vega gfx902]	AMD	raven	13,881	56,730	0.24	98 ^hrs 5 ^mins
59	GeForce GTX 670M GF114 [GeForce GTX 670M]	Nvidia	GF114	13,453	56,730	0.24	101 ^hrs 12 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA