Official Project Description
Class F Receptors and Patched Membrane Protein Class F Receptors and Patched are human proteins that are involved in the control of cell differentiation.
Over-activation/inactivation of these proteins has links to Basal Cell Carcinoma and Medulloblastoma.
Through simulations we aim to understand the activation mechanisms of these proteins, giving us a way to probe into the pathogenesis of the disease.