PROJECT #18908 RESEARCH FOR SIGNALING PROTEIN
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Impact of mutations on signaling proteins Mutations in proteins are often found to have dramatic functional consequences through changes in conformational dynamics, ligand binding, and association with signaling partners.

These changes sometimes lead to pathological outcomes.

Additionally, proteins involved in cell signaling are the target of over half of approved drugs.

This project aims to understand how a small number of mutations in signaling proteins can cause a dramatic change in how they modulate cell signaling pathways..

PROJECT INFO

Manager(s): Jiming Chen

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 37,892

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 03 October 2022 12:16:27

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	4,428,190	77,289	57.29	0 ^hrs 25 ^mins
2	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	4,374,288	76,208	57.40	0 ^hrs 25 ^mins
3	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	4,220,103	74,280	56.81	0 ^hrs 25 ^mins
4	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	4,114,410	73,955	55.63	0 ^hrs 26 ^mins
5	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	3,963,476	75,078	52.79	0 ^hrs 27 ^mins
6	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	3,593,969	72,306	49.70	0 ^hrs 29 ^mins
7	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	3,399,153	70,613	48.14	0 ^hrs 30 ^mins
8	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	3,257,404	70,048	46.50	1 ^hrs 31 ^mins
9	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	3,249,355	70,009	46.41	1 ^hrs 31 ^mins
10	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	2,727,154	65,718	41.50	1 ^hrs 35 ^mins
11	RTX A5000 GA102GL [RTX A5000]	Nvidia	GA102GL	2,556,511	64,386	39.71	1 ^hrs 36 ^mins
12	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	2,359,853	62,283	37.89	1 ^hrs 38 ^mins
13	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,146,739	61,247	35.05	1 ^hrs 41 ^mins
14	GeForce RTX 3070 Mobile / Max-Q GA104M [GeForce RTX 3070 Mobile / Max-Q]	Nvidia	GA104M	2,128,855	61,629	34.54	1 ^hrs 42 ^mins
15	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,119,149	60,587	34.98	1 ^hrs 41 ^mins
16	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	1,983,150	60,507	32.78	1 ^hrs 44 ^mins
17	GeForce RTX 3080 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3080 Mobile / Max-Q 8GB/16GB]	Nvidia	GA104M	1,811,423	57,487	31.51	1 ^hrs 46 ^mins
18	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,781,569	53,366	33.38	1 ^hrs 43 ^mins
19	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	1,722,352	56,673	30.39	1 ^hrs 47 ^mins
20	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,680,834	56,395	29.80	1 ^hrs 48 ^mins
21	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	1,537,344	54,063	28.44	1 ^hrs 51 ^mins
22	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	1,508,580	54,473	27.69	1 ^hrs 52 ^mins
23	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	1,377,568	52,905	26.04	1 ^hrs 55 ^mins
24	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,271,345	51,074	24.89	1 ^hrs 58 ^mins
25	Quadro RTX 4000 TU104GL [Quadro RTX 4000]	Nvidia	TU104GL	1,225,312	50,669	24.18	1 ^hrs 60 ^mins
26	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,136,420	49,615	22.90	1 ^hrs 3 ^mins
27	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,112,751	48,990	22.71	1 ^hrs 3 ^mins
28	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	987,611	46,197	21.38	1 ^hrs 7 ^mins
29	Geforce RTX 3050 GA106 [Geforce RTX 3050]	Nvidia	GA106	985,561	47,588	20.71	1 ^hrs 10 ^mins
30	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	964,040	46,452	20.75	1 ^hrs 9 ^mins
31	GeForce GTX 1660 Mobile TU116M [GeForce GTX 1660 Mobile]	Nvidia	TU116M	939,351	46,904	20.03	1 ^hrs 12 ^mins
32	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	788,315	43,748	18.02	1 ^hrs 20 ^mins
33	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	767,467	43,718	17.55	1 ^hrs 22 ^mins
34	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	709,319	43,185	16.43	1 ^hrs 28 ^mins
35	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	604,825	39,952	15.14	2 ^hrs 35 ^mins
36	P104-100 GP104 [P104-100]	Nvidia	GP104	599,378	40,533	14.79	2 ^hrs 37 ^mins
37	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	591,209	39,782	14.86	2 ^hrs 37 ^mins
38	P106-090 GP106 [P106-090]	Nvidia	GP106	332,165	32,555	10.20	2 ^hrs 21 ^mins
39	GeForce GTX 1050 LP GP107 [GeForce GTX 1050 LP] 1862	Nvidia	GP107	286,583	31,689	9.04	3 ^hrs 39 ^mins
40	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	224,328	29,259	7.67	3 ^hrs 8 ^mins
41	Quadro P1000 GP107GL [Quadro P1000]	Nvidia	GP107GL	203,369	27,811	7.31	3 ^hrs 17 ^mins
42	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	148,000	20,391	7.26	3 ^hrs 18 ^mins
43	Quadro M2000 GM206GL [Quadro M2000]	Nvidia	GM206GL	142,355	24,824	5.73	4 ^hrs 11 ^mins
44	GeForce GT 1030 GP108 [GeForce GT 1030] 1127	Nvidia	GP108	97,950	21,801	4.49	5 ^hrs 21 ^mins
45	Quadro K620 GM107GL [Quadro K620]	Nvidia	GM107GL	50,114	17,348	2.89	8 ^hrs 18 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA