PROJECT #18906 RESEARCH FOR SIGNALING PROTEIN
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Impact of mutations on signaling proteins Mutations in proteins are often found to have dramatic functional consequences through changes in conformational dynamics, ligand binding, and association with signaling partners.

These changes sometimes lead to pathological outcomes.

Additionally, proteins involved in cell signaling are the target of over half of approved drugs.

This project aims to understand how a small number of mutations in signaling proteins can cause a dramatic change in how they modulate cell signaling pathways..

PROJECT INFO

Manager(s): Jiming Chen

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 38,594

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 03 October 2022 12:16:27

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	5,375,615	68,560	78.41	0 ^hrs 18 ^mins
2	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	5,304,504	65,623	80.83	0 ^hrs 18 ^mins
3	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	4,573,712	62,198	73.53	0 ^hrs 20 ^mins
4	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,014,038	61,181	65.61	0 ^hrs 22 ^mins
5	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	3,490,144	57,647	60.54	0 ^hrs 24 ^mins
6	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	3,189,059	58,508	54.51	0 ^hrs 26 ^mins
7	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	3,117,127	55,838	55.82	0 ^hrs 26 ^mins
8	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	2,706,287	48,546	55.75	0 ^hrs 26 ^mins
9	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	2,585,753	52,362	49.38	0 ^hrs 29 ^mins
10	RTX A5000 GA102GL [RTX A5000]	Nvidia	GA102GL	2,567,187	52,950	48.48	0 ^hrs 30 ^mins
11	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	2,468,503	52,805	46.75	1 ^hrs 31 ^mins
12	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,346,965	50,826	46.18	1 ^hrs 31 ^mins
13	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,144,306	49,161	43.62	1 ^hrs 33 ^mins
14	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,051,415	49,510	41.43	1 ^hrs 35 ^mins
15	GeForce RTX 3070 Mobile / Max-Q GA104M [GeForce RTX 3070 Mobile / Max-Q]	Nvidia	GA104M	1,982,193	48,432	40.93	1 ^hrs 35 ^mins
16	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,736,311	46,485	37.35	1 ^hrs 39 ^mins
17	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	1,653,413	46,009	35.94	1 ^hrs 40 ^mins
18	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,282,733	41,648	30.80	1 ^hrs 47 ^mins
19	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,270,473	41,480	30.63	1 ^hrs 47 ^mins
20	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	1,147,437	40,786	28.13	1 ^hrs 51 ^mins
21	Quadro RTX 4000 TU104GL [Quadro RTX 4000]	Nvidia	TU104GL	1,133,804	40,010	28.34	1 ^hrs 51 ^mins
22	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,115,872	39,515	28.24	1 ^hrs 51 ^mins
23	Geforce RTX 3050 GA106 [Geforce RTX 3050]	Nvidia	GA106	1,067,268	39,057	27.33	1 ^hrs 53 ^mins
24	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	923,068	36,020	25.63	1 ^hrs 56 ^mins
25	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	914,005	37,025	24.69	1 ^hrs 58 ^mins
26	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	809,867	35,778	22.64	1 ^hrs 4 ^mins
27	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	706,174	33,914	20.82	1 ^hrs 9 ^mins
28	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	634,555	33,553	18.91	1 ^hrs 16 ^mins
29	P104-100 GP104 [P104-100]	Nvidia	GP104	627,932	33,393	18.80	1 ^hrs 17 ^mins
30	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	599,529	32,286	18.57	1 ^hrs 18 ^mins
31	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	398,415	23,568	16.90	1 ^hrs 25 ^mins
32	P106-090 GP106 [P106-090]	Nvidia	GP106	330,438	26,727	12.36	2 ^hrs 56 ^mins
33	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	217,003	23,090	9.40	3 ^hrs 33 ^mins
34	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	208,646	23,083	9.04	3 ^hrs 39 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA