PROJECT #18907 RESEARCH FOR SIGNALING PROTEIN
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Impact of mutations on signaling proteins Mutations in proteins are often found to have dramatic functional consequences through changes in conformational dynamics, ligand binding, and association with signaling partners.

These changes sometimes lead to pathological outcomes.

Additionally, proteins involved in cell signaling are the target of over half of approved drugs.

This project aims to understand how a small number of mutations in signaling proteins can cause a dramatic change in how they modulate cell signaling pathways..

PROJECT INFO

Manager(s): Jiming Chen

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 36,143

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 02 October 2022 12:16:25

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	4,837,423	78,954	61.27	0 ^hrs 24 ^mins
2	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,111,697	77,259	53.22	0 ^hrs 27 ^mins
3	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	3,959,224	73,225	54.07	0 ^hrs 27 ^mins
4	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	3,509,670	70,622	49.70	0 ^hrs 29 ^mins
5	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	3,428,521	71,528	47.93	1 ^hrs 30 ^mins
6	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	3,261,216	70,523	46.24	1 ^hrs 31 ^mins
7	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,233,376	70,385	45.94	1 ^hrs 31 ^mins
8	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	3,139,795	70,397	44.60	1 ^hrs 32 ^mins
9	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	3,066,239	67,976	45.11	1 ^hrs 32 ^mins
10	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	2,744,984	59,293	46.30	1 ^hrs 31 ^mins
11	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	2,645,646	65,237	40.55	1 ^hrs 36 ^mins
12	RTX A5000 GA102GL [RTX A5000]	Nvidia	GA102GL	2,594,756	65,356	39.70	1 ^hrs 36 ^mins
13	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,261,279	62,223	36.34	1 ^hrs 40 ^mins
14	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,257,013	62,582	36.06	1 ^hrs 40 ^mins
15	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,204,730	61,588	35.80	1 ^hrs 40 ^mins
16	GeForce RTX 3080 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3080 Mobile / Max-Q 8GB/16GB]	Nvidia	GA104M	2,114,371	60,235	35.10	1 ^hrs 41 ^mins
17	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	1,704,861	56,770	30.03	1 ^hrs 48 ^mins
18	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	1,688,304	56,401	29.93	1 ^hrs 48 ^mins
19	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,682,120	56,400	29.82	1 ^hrs 48 ^mins
20	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	1,668,359	57,001	29.27	1 ^hrs 49 ^mins
21	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	1,483,807	54,134	27.41	1 ^hrs 53 ^mins
22	Quadro RTX 4000 TU104GL [Quadro RTX 4000]	Nvidia	TU104GL	1,331,378	52,550	25.34	1 ^hrs 57 ^mins
23	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,283,404	51,541	24.90	1 ^hrs 58 ^mins
24	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,261,002	51,179	24.64	1 ^hrs 58 ^mins
25	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,201,369	50,205	23.93	1 ^hrs 0 ^mins
26	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,101,939	49,054	22.46	1 ^hrs 4 ^mins
27	Geforce RTX 3050 GA106 [Geforce RTX 3050]	Nvidia	GA106	1,087,144	48,857	22.25	1 ^hrs 5 ^mins
28	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	905,644	46,120	19.64	1 ^hrs 13 ^mins
29	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	881,131	45,373	19.42	1 ^hrs 14 ^mins
30	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	852,463	44,086	19.34	1 ^hrs 14 ^mins
31	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	722,426	43,107	16.76	1 ^hrs 26 ^mins
32	P104-100 GP104 [P104-100]	Nvidia	GP104	578,149	40,133	14.41	2 ^hrs 40 ^mins
33	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	398,326	34,882	11.42	2 ^hrs 6 ^mins
34	GeForce GTX 980M GM204 [GeForce GTX 980M] 3189	Nvidia	GM204	375,232	35,540	10.56	2 ^hrs 16 ^mins
35	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	357,596	33,561	10.66	2 ^hrs 15 ^mins
36	P106-090 GP106 [P106-090]	Nvidia	GP106	345,565	33,483	10.32	2 ^hrs 20 ^mins
37	Quadro M2000 GM206GL [Quadro M2000]	Nvidia	GM206GL	128,637	23,899	5.38	4 ^hrs 28 ^mins
38	Quadro P620 GP107GL [Quadro P620]	Nvidia	GP107GL	81,518	20,813	3.92	6 ^hrs 8 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA