PROJECT #18905 RESEARCH FOR SIGNALING PROTEIN
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Impact of mutations on signaling proteins Mutations in proteins are often found to have dramatic functional consequences through changes in conformational dynamics, ligand binding, and association with signaling partners.

These changes sometimes lead to pathological outcomes.

Additionally, proteins involved in cell signaling are the target of over half of approved drugs.

This project aims to understand how a small number of mutations in signaling proteins can cause a dramatic change in how they modulate cell signaling pathways..

PROJECT INFO

Manager(s): Jiming Chen

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 43,328

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 03 February 2023 06:15:10

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	5,979,078	80,180	74.57	0 ^hrs 19 ^mins
2	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	5,422,871	78,171	69.37	0 ^hrs 21 ^mins
3	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	5,395,935	78,084	69.10	0 ^hrs 21 ^mins
4	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	5,167,570	77,921	66.32	0 ^hrs 22 ^mins
5	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,346,861	72,934	59.60	0 ^hrs 24 ^mins
6	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	4,190,953	70,495	59.45	0 ^hrs 24 ^mins
7	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	3,513,750	68,300	51.45	0 ^hrs 28 ^mins
8	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	3,370,846	67,441	49.98	0 ^hrs 29 ^mins
9	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	2,986,470	64,793	46.09	0 ^hrs 31 ^mins
10	RTX A5000 GA102GL [RTX A5000]	Nvidia	GA102GL	2,751,663	62,825	43.80	0 ^hrs 33 ^mins
11	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	2,496,378	59,527	41.94	0 ^hrs 34 ^mins
12	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,429,129	61,157	39.72	0 ^hrs 36 ^mins
13	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,323,766	59,613	38.98	0 ^hrs 37 ^mins
14	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,320,747	59,150	39.23	0 ^hrs 37 ^mins
15	GeForce RTX 3080 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3080 Mobile / Max-Q 8GB/16GB]	Nvidia	GA104M	2,315,522	58,214	39.78	0 ^hrs 36 ^mins
16	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,848,330	54,857	33.69	0 ^hrs 43 ^mins
17	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	1,700,559	53,473	31.80	0 ^hrs 45 ^mins
18	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	1,700,175	53,395	31.84	0 ^hrs 45 ^mins
19	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,288,496	48,720	26.45	0 ^hrs 54 ^mins
20	Quadro RTX 4000 TU104GL [Quadro RTX 4000]	Nvidia	TU104GL	1,269,602	48,660	26.09	0 ^hrs 55 ^mins
21	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,243,481	47,898	25.96	0 ^hrs 55 ^mins
22	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,089,325	45,997	23.68	1 ^hrs 1 ^mins
23	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,055,509	45,158	23.37	1 ^hrs 2 ^mins
24	Geforce RTX 3050 GA106 [Geforce RTX 3050]	Nvidia	GA106	1,051,903	45,536	23.10	1 ^hrs 2 ^mins
25	GeForce GTX 1660 Mobile TU116M [GeForce GTX 1660 Mobile]	Nvidia	TU116M	981,185	44,648	21.98	1 ^hrs 6 ^mins
26	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	923,004	43,151	21.39	1 ^hrs 7 ^mins
27	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	885,966	42,882	20.66	1 ^hrs 10 ^mins
28	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	533,870	36,023	14.82	2 ^hrs 37 ^mins
29	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	419,459	33,179	12.64	2 ^hrs 54 ^mins
30	P106-090 GP106 [P106-090]	Nvidia	GP106	351,035	31,432	11.17	2 ^hrs 9 ^mins
31	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	212,609	27,210	7.81	3 ^hrs 4 ^mins
32	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	128,546	22,540	5.70	4 ^hrs 12 ^mins
33	Quadro K2200 GM107GL [Quadro K2200]	Nvidia	GM107GL	126,280	22,884	5.52	4 ^hrs 21 ^mins
34	GeForce GT 1030 GP108 [GeForce GT 1030] 1127	Nvidia	GP108	100,953	20,875	4.84	5 ^hrs 58 ^mins
35	Quadro K620 GM107GL [Quadro K620]	Nvidia	GM107GL	54,447	17,102	3.18	8 ^hrs 32 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA