Folding project #16576, LIQUID-PHASE-SEPARATION research

Research section Research projects and references

Project #16576 overview

Project Summary AI Beta

This project simulates how tiny protein clumps called condensates change when different peptides (small proteins) are added. They look at how these changes affect the clump's size and shape, especially when RNA is also included. Different concentrations of peptides and RNA are tested to see how it impacts the clumps.

Automated summary; simplified and may not be fully accurate.

Project team

Manager(s): Prof. Xuhui Huang
Institution: Hong Kong University of Science and Technology

Work unit

Atoms: 441,704
Core: 0x22
Status: Public

Source material

Official Project Description

16550: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16551, 16560, 16568: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16552, 16561, 16567: Liquid-liquid Phase separation simulation for condensate and added peptide ARG 16553, 16562, 16569: Liquid-liquid Phase separation simulation for condensate and added peptide LYS 16554: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA 16555, 16577: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA 16556: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA 16557, 16563, 16575: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA, concentration 3.7 mM 16558, 16564, 16566, 16574: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA, concentration 3.7 mM 16559, 16565, 16576: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA, concentration 3.7 mM 16570: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM 16571: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide ADMA 16572: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide ARG 16573: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide LYS.

Reading reference

Related Terms Glossary AI Beta

Automated high-level definitions; simplified and may not be fully accurate.

Liquid-liquid Phase separation

Separation of components in a liquid based on their solubility

Scientific: BiotechnologyBiochemistry / Molecular Biology

Liquid-liquid phase separation is a process where different molecules within a liquid mixture separate into distinct phases due to variations in their solubility. This phenomenon plays a crucial role in various biological processes, including the formation of organelles, protein aggregation, and gene regulation.

Condensate

A dense, concentrated substance that forms when molecules aggregate together

Scientific: PharmaceuticalsBiochemistry / Cellular Biology

Condensates are dense, concentrated regions within a cell or solution formed by the aggregation of specific molecules. They can play crucial roles in regulating cellular processes and compartmentalizing various functions.

Peptide

A short chain of amino acids linked together

Scientific: MedicineBiochemistry / Protein Chemistry

Peptides are short chains of amino acids, the building blocks of proteins. They often play vital roles in biological processes, acting as hormones, neurotransmitters, and signaling molecules.

ADMA

Asparagine-Derived Methylarginine

Acronym: ResearchBiochemistry / Pharmacology

ADMA is a molecule derived from the amino acid asparagine and plays a role in regulating blood pressure.

ARG

Arginine

Acronym: ResearchBiochemistry / Protein Chemistry

ARG is an acronym for the amino acid arginine, which plays important roles in protein structure and function.

LYS

Lysine

Acronym: ResearchBiochemistry / Protein Chemistry

LYS is an acronym for the amino acid lysine, which is essential for various biological processes.

RNA

Ribonucleic Acid

Scientific: MedicineBiochemistry / Molecular Biology

RNA is a type of nucleic acid that plays a vital role in protein synthesis and other cellular processes.

mM

Millimolar

Scientific: ResearchChemistry / Analytical Chemistry

mM stands for millimolar, a unit of concentration used to express the amount of solute in a solution.

GPU PPD Averages

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 4090 AD102 [GeForce RTX 4090]	Nvidia	AD102	23,396,151	1,369,497	17.08	1 ^hrs 24 ^mins
2	GeForce RTX 4080 AD103 [GeForce RTX 4080]	Nvidia	AD103	14,752,012	1,182,854	12.47	1 ^hrs 55 ^mins
3	GeForce RTX 4070 Ti AD104 [GeForce RTX 4070 Ti]	Nvidia	AD104	12,338,963	1,083,469	11.39	2 ^hrs 6 ^mins
4	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	9,050,827	988,551	9.16	2 ^hrs 37 ^mins
5	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	8,236,773	973,295	8.46	2 ^hrs 50 ^mins
6	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	7,579,136	947,543	8.00	3 ^hrs 0 ^mins
7	GeForce RTX 4070 AD104 [GeForce RTX 4070]	Nvidia	AD104	7,479,256	947,974	7.89	3 ^hrs 3 ^mins
8	GeForce RTX 3080 12GB GA102 [GeForce RTX 3080 12GB]	Nvidia	GA102	7,409,275	934,727	7.93	3 ^hrs 2 ^mins
9	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	6,195,600	877,490	7.06	3 ^hrs 24 ^mins
10	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	5,768,932	861,792	6.69	3 ^hrs 35 ^mins
11	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	5,130,392	834,628	6.15	3 ^hrs 54 ^mins
12	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	4,791,648	822,743	5.82	4 ^hrs 7 ^mins
13	Radeon RX 7900XT/XTX Navi 31 [Radeon RX 7900XT/XTX]	AMD	Navi 31	4,501,614	792,500	5.68	4 ^hrs 14 ^mins
14	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,482,147	805,601	5.56	4 ^hrs 19 ^mins
15	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	3,979,487	770,476	5.16	4 ^hrs 39 ^mins
16	Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT]	AMD	Navi 21	3,567,688	739,532	4.82	4 ^hrs 58 ^mins
17	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	3,508,803	738,210	4.75	5 ^hrs 3 ^mins
18	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,504,808	737,940	4.75	5 ^hrs 3 ^mins
19	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	2,919,875	690,538	4.23	5 ^hrs 41 ^mins

20	GeForce RTX 3070 Mobile / Max-Q GA104M [GeForce RTX 3070 Mobile / Max-Q]	Nvidia	GA104M	2,732,717	678,028	4.03	5 ^hrs 57 ^mins
21	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,701,942	672,873	4.02	5 ^hrs 59 ^mins
22	RTX A4000 GA104GL [RTX A4000]	Nvidia	GA104GL	2,653,283	652,573	4.07	5 ^hrs 54 ^mins
23	Radeon RX 6800/6800XT/6900XT Navi 21 [Radeon RX 6800/6800XT/6900XT]	AMD	Navi 21	2,546,602	667,473	3.82	6 ^hrs 17 ^mins
24	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	2,446,565	653,751	3.74	6 ^hrs 25 ^mins
25	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	2,439,457	683,431	3.57	6 ^hrs 43 ^mins
26	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A]	Nvidia	TU106	2,296,169	684,890	3.35	7 ^hrs 10 ^mins
27	GeForce RTX 3060 GA106 [GeForce RTX 3060]	Nvidia	GA106	2,193,428	620,791	3.53	6 ^hrs 48 ^mins
28	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,165,931	633,503	3.42	7 ^hrs 1 ^mins
29	TITAN X GP102 [TITAN X] 6144	Nvidia	GP102	2,161,298	620,484	3.48	6 ^hrs 53 ^mins
30	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,043,716	585,144	3.49	6 ^hrs 52 ^mins
31	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,008,853	607,974	3.30	7 ^hrs 16 ^mins
32	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	1,893,764	613,953	3.08	7 ^hrs 47 ^mins
33	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	1,850,615	637,198	2.90	8 ^hrs 16 ^mins
34	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,684,128	577,343	2.92	8 ^hrs 14 ^mins
35	RTX A2000 GA106 [RTX A2000]	Nvidia	GA106	1,235,254	515,641	2.40	10 ^hrs 1 ^mins
36	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,202,535	548,767	2.19	10 ^hrs 57 ^mins
37	Radeon RX 6700/6700XT/6800M Navi 22 XT-XL [Radeon RX 6700/6700XT/6800M]	AMD	Navi 22 XT-XL	1,078,847	470,485	2.29	10 ^hrs 28 ^mins
38	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,076,074	498,212	2.16	11 ^hrs 7 ^mins
39	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	1,008,962	479,438	2.10	11 ^hrs 24 ^mins

40	Radeon RX 6650XT Navi 23 [Radeon RX 6650XT]	AMD	Navi 23	996,945	489,780	2.04	11 ^hrs 47 ^mins
41	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	970,238	475,256	2.04	11 ^hrs 45 ^mins
42	P104-100 GP104 [P104-100]	Nvidia	GP104	962,028	478,234	2.01	11 ^hrs 56 ^mins
43	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	955,234	475,853	2.01	11 ^hrs 57 ^mins
44	GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q]	Nvidia	GA106M	944,588	496,046	1.90	12 ^hrs 36 ^mins
45	GeForce GTX 1660 Mobile TU116M [GeForce GTX 1660 Mobile]	Nvidia	TU116M	933,860	417,276	2.24	10 ^hrs 43 ^mins
46	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	846,825	460,340	1.84	13 ^hrs 3 ^mins
47	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	749,440	433,777	1.73	13 ^hrs 53 ^mins
48	GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER]	Nvidia	TU116	741,956	437,588	1.70	14 ^hrs 9 ^mins
49	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	647,824	433,287	1.50	16 ^hrs 3 ^mins
50	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	626,886	412,826	1.52	15 ^hrs 48 ^mins
51	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	624,248	425,063	1.47	16 ^hrs 21 ^mins
52	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	461,263	391,737	1.18	20 ^hrs 23 ^mins
53	P106-090 GP106 [P106-090]	Nvidia	GP106	291,513	322,413	0.90	26 ^hrs 33 ^mins
54	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	286,119	360,936	0.79	30 ^hrs 17 ^mins
55	GeForce GTX 1050 Mobile GP107M [GeForce GTX 1050 Mobile]	Nvidia	GP107M	217,256	294,092	0.74	32 ^hrs 29 ^mins
56	GeForce GTX 1050 LP GP107 [GeForce GTX 1050 LP] 1862	Nvidia	GP107	118,735	282,242	0.42	57 ^hrs 3 ^mins
57	GeForce GT 1030 GP108 [GeForce GT 1030]	Nvidia	GP108	106,064	229,957	0.46	52 ^hrs 2 ^mins
58	GeForce MX450 TU117M [GeForce MX450]	Nvidia	TU117M	103,462	203,420	0.51	47 ^hrs 11 ^mins

Research: LIQUID-PHASE-SEPARATION Folding Project #16576

Project Summary AI Beta

Project team

Work unit

Official Project Description

Hardware Performance for Project 16576

GPU PPD Averages

Research: LIQUID-PHASE-SEPARATION Folding Project #16576

Project Summary AI Beta

Project team

Work unit

Related projects

GPU PPD Averages