Folding project #16570, LIQUID-PHASE-SEPARATION research

Research section Research projects and references

Project #16570 overview

Project Summary AI Beta

This project simulates how different molecules clump together in a cell. They looked at how adding certain peptides (ADMA, ARG, LYS) and RNA to existing clumps affects their size and shape. Some simulations included higher concentrations of these molecules.

Automated summary; simplified and may not be fully accurate.

Project team

Manager(s): Prof. Xuhui Huang
Institution: Hong Kong University of Science and Technology

Work unit

Atoms: 469,796
Core: 0x22
Status: Public

Source material

Official Project Description

16550: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16551, 16560, 16568: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16552, 16561, 16567: Liquid-liquid Phase separation simulation for condensate and added peptide ARG 16553, 16562, 16569: Liquid-liquid Phase separation simulation for condensate and added peptide LYS 16554: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA 16555, 16577: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA 16556: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA 16557, 16563, 16575: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA, concentration 3.7 mM 16558, 16564, 16566, 16574: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA, concentration 3.7 mM 16559, 16565, 16576: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA, concentration 3.7 mM 16570: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM 16571: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide ADMA 16572: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide ARG 16573: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide LYS.

Reading reference

Related Terms Glossary AI Beta

Automated high-level definitions; simplified and may not be fully accurate.

Liquid-liquid Phase separation

The process where two immiscible liquids separate into distinct phases.

Technical: BiotechnologyBiochemistry / Molecular Biology

Liquid-liquid phase separation is a natural phenomenon where two liquids that don't mix, like oil and water, form separate layers. In biochemistry, this process is important for how cells organize their components and carry out essential functions.

Condensate

A concentrated mixture of molecules in a cellular context.

Scientific: BiotechnologyBiochemistry / Molecular Biology

In biology, a condensate is like a dense drop or clump formed by molecules grouping together. These condensates are important for organizing cell functions and carrying out specific processes.

Peptide

A short chain of amino acids linked together.

Scientific: BiotechnologyBiochemistry / Molecular Biology

Peptides are like mini proteins made up of a few building blocks called amino acids. They play many important roles in the body, such as signaling and carrying out specific functions.

ADMA

Asparagine-derived methylarginine analog.

Acronym: BiotechnologyBiochemistry / Molecular Biology

ADMA is a molecule that acts like a natural protein in the body. Scientists use it to study how proteins affect cellular processes.

ARG

Arginine.

Acronym: BiotechnologyBiochemistry / Molecular Biology

ARG is a shortened form of the amino acid arginine. Arginine plays several roles in the body, including building proteins and supporting muscle growth.

LYS

Lysine.

Acronym: BiotechnologyBiochemistry / Molecular Biology

LYS is a shortened form of the amino acid lysine. Lysine is important for building proteins and helping the body absorb calcium.

RNA

Ribonucleic acid.

Scientific: BiotechnologyBiochemistry / Molecular Biology

RNA is a molecule that plays a crucial role in carrying genetic information from DNA to the parts of the cell that make proteins.

GPU PPD Averages

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 4090 AD102 [GeForce RTX 4090]	Nvidia	AD102	26,734,374	1,348,192	19.83	1 ^hrs 13 ^mins
2	GeForce RTX 4080 AD103 [GeForce RTX 4080]	Nvidia	AD103	18,468,363	1,200,663	15.38	1 ^hrs 34 ^mins
3	GeForce RTX 4070 Ti AD104 [GeForce RTX 4070 Ti]	Nvidia	AD104	14,522,914	1,087,018	13.36	1 ^hrs 48 ^mins
4	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	10,513,543	998,647	10.53	2 ^hrs 17 ^mins
5	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	9,843,114	970,259	10.14	2 ^hrs 22 ^mins
6	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	9,456,544	960,738	9.84	2 ^hrs 26 ^mins
7	GeForce RTX 3080 12GB GA102 [GeForce RTX 3080 12GB]	Nvidia	GA102	8,904,340	937,955	9.49	2 ^hrs 32 ^mins
8	GeForce RTX 4070 AD104 [GeForce RTX 4070]	Nvidia	AD104	8,700,317	931,282	9.34	2 ^hrs 34 ^mins
9	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	8,089,148	904,452	8.94	2 ^hrs 41 ^mins
10	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	7,792,590	897,833	8.68	2 ^hrs 46 ^mins
11	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	6,480,924	849,653	7.63	3 ^hrs 9 ^mins
12	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	6,204,902	838,652	7.40	3 ^hrs 15 ^mins
13	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	5,673,788	816,407	6.95	3 ^hrs 27 ^mins
14	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	5,119,375	789,996	6.48	3 ^hrs 42 ^mins
15	Radeon RX 7900XT/XTX Navi 31 [Radeon RX 7900XT/XTX]	AMD	Navi 31	5,074,224	781,001	6.50	3 ^hrs 42 ^mins
16	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	4,454,313	751,479	5.93	4 ^hrs 3 ^mins
17	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	4,394,316	746,557	5.89	4 ^hrs 5 ^mins
18	Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT]	AMD	Navi 21	3,892,136	717,689	5.42	4 ^hrs 26 ^mins
19	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	3,766,393	700,616	5.38	4 ^hrs 28 ^mins

20	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	3,629,946	696,347	5.21	4 ^hrs 36 ^mins
21	RTX A4000 GA104GL [RTX A4000]	Nvidia	GA104GL	3,580,906	684,066	5.23	4 ^hrs 35 ^mins
22	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A]	Nvidia	TU106	3,408,723	709,404	4.81	4 ^hrs 60 ^mins
23	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	3,262,898	670,662	4.87	4 ^hrs 56 ^mins
24	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	3,154,259	684,516	4.61	5 ^hrs 12 ^mins
25	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	3,153,966	663,500	4.75	5 ^hrs 3 ^mins
26	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	3,007,698	662,587	4.54	5 ^hrs 17 ^mins
27	Radeon RX 6950 XT Navi 21 [Radeon RX 6950 XT]	AMD	Navi 21	2,967,610	633,909	4.68	5 ^hrs 8 ^mins
28	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,909,946	649,833	4.48	5 ^hrs 22 ^mins
29	GeForce RTX 3060 GA106 [GeForce RTX 3060]	Nvidia	GA106	2,741,238	638,201	4.30	5 ^hrs 35 ^mins
30	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	2,720,381	646,612	4.21	5 ^hrs 42 ^mins
31	GeForce RTX 3080 Mobile / Max-Q 8GB/16GB GA104M [GeForce RTX 3080 Mobile / Max-Q 8GB/16GB]	Nvidia	GA104M	2,653,018	568,326	4.67	5 ^hrs 8 ^mins
32	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,542,120	604,919	4.20	5 ^hrs 43 ^mins
33	Radeon RX 6800/6800XT/6900XT Navi 21 [Radeon RX 6800/6800XT/6900XT]	AMD	Navi 21	2,507,923	606,166	4.14	5 ^hrs 48 ^mins
34	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	2,250,497	597,500	3.77	6 ^hrs 22 ^mins
35	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,124,538	543,456	3.91	6 ^hrs 8 ^mins
36	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	1,659,176	540,451	3.07	7 ^hrs 49 ^mins
37	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,425,065	534,211	2.67	8 ^hrs 60 ^mins
38	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,395,529	508,051	2.75	8 ^hrs 44 ^mins
39	Radeon RX 6700/6700XT/6800M Navi 22 XT-XL [Radeon RX 6700/6700XT/6800M]	AMD	Navi 22 XT-XL	1,314,127	504,980	2.60	9 ^hrs 13 ^mins

40	GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q]	Nvidia	GA106M	1,259,209	510,368	2.47	9 ^hrs 44 ^mins
41	RTX A2000 GA106 [RTX A2000]	Nvidia	GA106	1,245,226	517,859	2.40	9 ^hrs 59 ^mins
42	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	1,241,221	492,354	2.52	9 ^hrs 31 ^mins
43	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,218,105	502,879	2.42	9 ^hrs 54 ^mins
44	P104-100 GP104 [P104-100]	Nvidia	GP104	1,177,004	481,502	2.44	9 ^hrs 49 ^mins
45	GeForce GTX 960 GM206 [GeForce GTX 960] 2308	Nvidia	GM206	1,174,745	337,484	3.48	6 ^hrs 54 ^mins
46	Radeon RX 6650XT Navi 23 [Radeon RX 6650XT]	AMD	Navi 23	1,145,670	478,282	2.40	10 ^hrs 1 ^mins
47	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,016,901	462,476	2.20	10 ^hrs 55 ^mins
48	GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER]	Nvidia	TU116	895,174	444,676	2.01	11 ^hrs 55 ^mins
49	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	842,479	443,814	1.90	12 ^hrs 39 ^mins
50	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	690,458	401,038	1.72	13 ^hrs 56 ^mins
51	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	555,701	364,126	1.53	15 ^hrs 44 ^mins
52	GeForce GTX 1060 Mobile GP106M [GeForce GTX 1060 Mobile]	Nvidia	GP106M	522,201	366,571	1.42	16 ^hrs 51 ^mins
53	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	452,999	397,913	1.14	21 ^hrs 5 ^mins
54	GeForce GTX 1050 Ti GP107 [GeForce GTX 1050 Ti] 2138	Nvidia	GP107	357,830	336,707	1.06	22 ^hrs 35 ^mins
55	P106-090 GP106 [P106-090]	Nvidia	GP106	310,269	290,858	1.07	22 ^hrs 30 ^mins
56	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	284,447	300,743	0.95	25 ^hrs 22 ^mins
57	Quadro P2200 GP106GL [Quadro P2200]	Nvidia	GP106GL	251,087	328,116	0.77	31 ^hrs 22 ^mins
58	GeForce GTX 1050 LP GP107 [GeForce GTX 1050 LP] 1862	Nvidia	GP107	201,314	268,749	0.75	32 ^hrs 2 ^mins
59	GeForce GT 1030 GP108 [GeForce GT 1030]	Nvidia	GP108	133,259	233,558	0.57	42 ^hrs 4 ^mins

60	GeForce MX450 TU117M [GeForce MX450]	Nvidia	TU117M	131,963	207,015	0.64	37 ^hrs 39 ^mins

Research: LIQUID-PHASE-SEPARATION Folding Project #16570

Project Summary AI Beta

Project team

Work unit

Official Project Description

Hardware Performance for Project 16570

GPU PPD Averages

Research: LIQUID-PHASE-SEPARATION Folding Project #16570

Project Summary AI Beta

Project team

Work unit

Related projects

GPU PPD Averages